Gene Information

Name : cadA2 (LP6_1018)
Accession : YP_008062733.1
Strain : Legionella pneumophila Thunder Bay
Genome accession: NC_021350
Putative virulence/resistance : Resistance
Product : cadmium translocating P-type ATPase CadA
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.5
Position : 1140679 - 1142823 bp
Length : 2145 bp
Strand : +
Note : -

DNA sequence :
ATGATGACAGCTCCGCTCACCTTAACCACTTTTTTTGTTGCAGGACTTGATTGTCAGGCTGAAGAACAATTAATCAGGCG
GCAATTGCAAGCTATCCCTGAAGTGGAAAAGATGGATTTTAATTTTATTGCTGAAGAAGTAACGGTTCATCATCGATTAC
CCACCATTGAACCTATACAACAGCAGATAGAAGCCTTAGGGATGAGCGTGCGCGCCAAACAAAGCACCCCTAGCGACAAG
GTTCAGGAAAAACTTAAATTTGATGCCTCTTGGCAGATTCTTGCATTATCAGGTCTATTGGCTCTTTGCTCCGAAATAGC
AGCTTATCTTTTGGCAACAGAGCAATCTCTATGGGCCATTATTCCTGCCTTACTGGCCATTATTCTCAGTGGACCTCCTA
CTTTTAAAAAAGGTTGGCTTGCTTTGCGCACAAAAGCCATGAACATTAACAGTCTAATGCTCATTGCCATAACAGGGGCT
ATCTTTATCGGTGATTGGCCTGAGGCGGCTATGGTTACTGTTTTGTTTGCATTGGCGGAACGAATAGAGCGTTATTCCTT
AGACAAAGCACGTCTGGCTATTCGAAGCTTGATGCAGATTGTTCCTGATGTGGCTCAAGTGAAAACAGCTAATGGTCAAT
GGCAAACTTTACTGGTCGAGGAAGTGCCACTGGGTGCTGTTTTTAGAGTTAAGCCTGGTGAGCGTATTCCATTGGATGGT
GAGGTGGTTTCAGGTCAAAGTACAGTCAACCAAGCTCCTATTACCGGGGAATCCATGCCAGTGAGTAAGCAGATAGGTGA
TTCTGTTTTTGCCGGCTCTTTAAATGAGCATGGGGCTTTTGAAGCGAAGGTGAGCAAAGCGTCAGGCGATACGCTGCTCG
CTAAAATTGGTAAAGCGATTGAACAGGCGCAAGCTGAGCGGGCCCCAACGCAACGATTTGTTGACGAATTTGCAAGATAC
TATACGCCTATTATGGTATTGATTGCTGTTCTTGTCGCTTTAATTCCTCCTTTCGTGTTGGGATATTCTTTTTATGATTG
GATCTATAAGGCGTTGACTTTATTAGTTATTGCCTGTCCTTGTGCCCTGGTCATTTCAACACCAGTAACAGTGGTGAGTG
GCTTGGCTGCCTCTGCCAAACATGGGCTTCTCATCAAAGGAGGAAGCTATTTAGAGACGGGTTATCGCTTACAGTTAATT
GCACTGGATAAAACTGGTACCTTAACAGAGGGCAAACCGGTGGTAACCGATTTTATTACTTATGATAAAAGTCAAACCAA
TGAACACTTGTTGTTGCTTGCTGCAAGTCTTGACAGCCACTCCGAGCACCCCGTAGCTCATGCCCTAGTGGCATATTGGC
AGCAAGAGCATCCTGATAAATCATTGCTTTCAGTGGAACGGTTTTCAGCGCTTCCTGGGCGAGGCGTGAAAGGTGCCATC
CAGGGGGAATTGTATTATGTAGGCAATCATCAATTAGCAGAAGACAACAAAGTCTGTTGTTTAGAGGTTGAGCAAGAATT
GAAACGACTGGAAGAAGAAGGAAAAACTACTGTTATATTAAGCAATAGCACTACGGCCTTGGCTATTTTTGCAGTGGCAG
ATACGCTTCGAGCCAACAGTCGAGAGGCGATTGAATCATTGCATCGACAAAGGATAAAAACGGCGATGTTAACAGGTGAT
AATGCTCTAACCGCTCAAGCCATTGCCAAACAAGTCGGCATTGATGAAATCCAAGCTAATATATTACCAACAGAAAAAAT
GCAGGCTATCAATAAACTCTTAGAACAATATCAGGCTGTGGGCATGGTGGGAGATGGCATTAATGATGCACCTGCTTTAG
CGAAAGCCACTATTAGCTTTGCGATGGGTAAGGGAACAGATACCGCTTTAGAGACAGCGGATGTGGTATTAATGAATGAT
AATTTAGCCATGCTTCCTCTGTACATTGACTTAAGCCGGAAGACAGTGCGAATTTTATGGCAAAACATTAGTCTATCCTT
GGTTATTAAAACGGTGTTTTTTATTTTAGCACTTGGAGGAATGGCTACCCTTTGGATGGCGGTTTTTGCTGACATGGGGG
CTAGTTTGATTGTGGTTATGAATGGGCTACGATTGTTGAATTCAAATAAAACGAAGAATCATTAA

Protein sequence :
MMTAPLTLTTFFVAGLDCQAEEQLIRRQLQAIPEVEKMDFNFIAEEVTVHHRLPTIEPIQQQIEALGMSVRAKQSTPSDK
VQEKLKFDASWQILALSGLLALCSEIAAYLLATEQSLWAIIPALLAIILSGPPTFKKGWLALRTKAMNINSLMLIAITGA
IFIGDWPEAAMVTVLFALAERIERYSLDKARLAIRSLMQIVPDVAQVKTANGQWQTLLVEEVPLGAVFRVKPGERIPLDG
EVVSGQSTVNQAPITGESMPVSKQIGDSVFAGSLNEHGAFEAKVSKASGDTLLAKIGKAIEQAQAERAPTQRFVDEFARY
YTPIMVLIAVLVALIPPFVLGYSFYDWIYKALTLLVIACPCALVISTPVTVVSGLAASAKHGLLIKGGSYLETGYRLQLI
ALDKTGTLTEGKPVVTDFITYDKSQTNEHLLLLAASLDSHSEHPVAHALVAYWQQEHPDKSLLSVERFSALPGRGVKGAI
QGELYYVGNHQLAEDNKVCCLEVEQELKRLEEEGKTTVILSNSTTALAIFAVADTLRANSREAIESLHRQRIKTAMLTGD
NALTAQAIAKQVGIDEIQANILPTEKMQAINKLLEQYQAVGMVGDGINDAPALAKATISFAMGKGTDTALETADVVLMND
NLAMLPLYIDLSRKTVRILWQNISLSLVIKTVFFILALGGMATLWMAVFADMGASLIVVMNGLRLLNSNKTKNH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 6e-153 52
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 7e-116 41
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 8e-116 41
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 3e-118 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadA2 YP_008062733.1 cadmium translocating P-type ATPase CadA BAC0298 Protein 1e-148 52
cadA2 YP_008062733.1 cadmium translocating P-type ATPase CadA BAC0461 Protein 2e-76 41