Gene Information

Name : AHML_21450 (AHML_21450)
Accession : YP_008045393.1
Strain : Aeromonas hydrophila ML09-119
Genome accession: NC_021290
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone protein ClpB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4823165 - 4825738 bp
Length : 2574 bp
Strand : -
Note : COG0542 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGCGCCTCGATCGCCTGACCAGCAAATTCCAGATTGCTATTTCCGATGCCCAGTCTTTGGCACTGGGTCGTGACCACCA
ATTCATCGAACCCGTTCACCTGATGACCGCCCTGGTCAATCAGGATGGCGGCTCCATCCGCCCGCTGCTCACCTTGACTG
GGATGGACATCAATTCTCTGCGCTCGCGCCTCGGCGAGGAGCTGGATCGTCTGCCGCGCGTCAGCGGCGTGGAAGGGGAC
GTACAGCTCTCCAACGGCCTTGGCCGGCTGCTCAACGTCTGCGACAAGCTGGCTCAGCAGCGCAAGGATCAGTTCATCTC
ATCCGAACTGTTCGTGCTGGCGGCCCTCGACGAGAAGGGGACGCTGGGCGAGCTGCTGCGTGCCCAGGGGCTGACCAAGG
AAAAACTCGAAGCGGCCATCGACAAGGTGCGTGGCGGCAAGAAGGTGGAAGATGCCAACGCCGAGGAGAATCGTCAGGCG
CTGGAGAAATACACCATCGATCTGACCGAGCGGGCCGAGATCGGCAAGCTCGACCCGGTGATCGGCCGGGATGACGAGAT
CCGCCGCACCATCCAAGTGCTGCAACGCCGTACCAAGAACAACCCGGTGCTGATCGGCGCCCCCGGCGTCGGCAAGACCG
CCATCGTCGAAGGGCTGGCCCAGCGCATCATCAATGGTGAGGTGCCGGAGGGGCTGAAGAACAAGCGGGTGCTGTCGCTG
GACATGGGGGCGCTGGTGGCCGGTGCCAAGTATCGCGGCGAGTTCGAGGAGCGGCTCAAGGCGGTGCTGAACGATCTTGC
CAAGGAGGAGGGCAACGTCATCCTCTTCATCGACGAGCTGCACACCATGGTCGGCGCCGGCAAGGGTGAAGGGGCCATGG
ATGCGGGCAACATGCTCAAACCTGCGCTGGCCCGTGGCGACCTGCACTGCGTCGGGGCCACCACCCTGGATGAGTACCGC
CAGTACATCGAGAAGGATGCCGCGCTGGAGCGCCGCTTCCAGAAGGTGCTGGTGGAAGAGCCGAGCGTGGAGGATACCAT
CGCCATCCTGCGCGGCCTGAAGGAGCGTTACGAACTGCACCACCACGTGCAGATCACCGACCCCGCCATCGTGGCGGCGG
CCCAGCTGTCGCACCGCTACATCGCGGATCGCCAGCTGCCGGACAAGGCCATCGACCTCATCGACGAGGCGGCGGCCAGC
ATCCGGCTGCAGATCGACTCCAAGCCCGAGTCCCTTGACCGGCTCGAGCGACGCATCATCCAGCTCAAGCTGGAGCAGCA
GGCGCTGATGAAGGAGGATGACGACGCCAGTCGCAAGCGGCTCGAGCTGATCAATCAGGAAATCAGCGAAAAAGATCGGG
AATACAACGAGCTGGATGAGGTATGGAAGGCCGAGAAGGCCGCCCTCGCCGGCACCCAGCACATCAAGGCGGCCCTCGAG
CAGGCCCGCCAGGATCTCGACGTGGCGCGCCGCGCAGGCGATCTGGGCCGGATGTCCGAGCTGCAGTACGGCCGCATTCC
AGAGCTGGAGAAACAGCTGGATCTCGCCACCCAGGCGGAGATGCAGGAGACCAGCCTGCTGCGCAACCGGGTCACCGACG
TGGAGATAGCCGATGTCTTGGCGCGCTGGACCGGCATTCCGGTGGCCCGCATGCTGGAAGGGGAGCGCGACAAGCTGCTG
CGGATGGAAGATCAGCTGCACAGCCGGGTGATCGGCCAGGAGGAGGCGGTCGAGGCGGTTTCCAACGCCATTCGCCGCTC
CCGCGCCGGGCTGTCCGATCCGAACCGCCCCATCGGCTCCTTCCTGTTCCTGGGGCCCACCGGGGTGGGCAAGACCGAGC
TGTGCAAGGCGCTGGCCGAGTTCCTGTTCGATACCCAGGACGCCATGGTGCGGATCGACATGTCGGAGTTCATGGAGAAA
CACAGCGTGGCCCGTCTGGTGGGGGCGCCTCCGGGATACGTGGGTTATGAGGAGGGCGGTTATCTGACCGAGGCGGTACG
CCGTCGCCCCTACTCGGTGATCCTGCTGGATGAAGTGGAGAAGGCACACCCGGATGTGTTCAACATCCTGCTGCAGGTGC
TGGACGATGGCCGCCTGACCGATGGTCAGGGTCGGACCGTCGATTTTCGCAACTCGGTGGTGATCATGACCTCCAACCTC
GGGTCGGATCTCATTCAGGAGCACCACTCCGAGAAGGATTACGACGAGATGAAAGGCATGCTGATGGAGGTGCTGACCCG
CAGCTTCCGGCCGGAGTTCATCAACCGGATCGACGAGACGGTGGTGTTCCACCCGCTCGGCGAGGAGCACATCAAGTCCA
TCGCCCGCATCCAGCTCAAGAGCCTGATGGGTCGACTGGAGTCCCAGGGTTACGAGGTGGAAGTGAGCGAGGCGCTGCTC
GAGAAGCTGGTGCACGCCGGGTTCGACCCCGTCTACGGGGCGCGTCCCCTCAAGCGGGCGATCCAGCACAAGGTGGAGAA
CCCGCTGGCGCAGGCGCTGCTCTCCGGCCGCATCGTGCCGGGCAAAAAGCTGGTGCTGGGGGCCGACAGCAACGGCCTCA
CCATGACCCAGTAA

Protein sequence :
MRLDRLTSKFQIAISDAQSLALGRDHQFIEPVHLMTALVNQDGGSIRPLLTLTGMDINSLRSRLGEELDRLPRVSGVEGD
VQLSNGLGRLLNVCDKLAQQRKDQFISSELFVLAALDEKGTLGELLRAQGLTKEKLEAAIDKVRGGKKVEDANAEENRQA
LEKYTIDLTERAEIGKLDPVIGRDDEIRRTIQVLQRRTKNNPVLIGAPGVGKTAIVEGLAQRIINGEVPEGLKNKRVLSL
DMGALVAGAKYRGEFEERLKAVLNDLAKEEGNVILFIDELHTMVGAGKGEGAMDAGNMLKPALARGDLHCVGATTLDEYR
QYIEKDAALERRFQKVLVEEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAAQLSHRYIADRQLPDKAIDLIDEAAAS
IRLQIDSKPESLDRLERRIIQLKLEQQALMKEDDDASRKRLELINQEISEKDREYNELDEVWKAEKAALAGTQHIKAALE
QARQDLDVARRAGDLGRMSELQYGRIPELEKQLDLATQAEMQETSLLRNRVTDVEIADVLARWTGIPVARMLEGERDKLL
RMEDQLHSRVIGQEEAVEAVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKALAEFLFDTQDAMVRIDMSEFMEK
HSVARLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNSVVIMTSNL
GSDLIQEHHSEKDYDEMKGMLMEVLTRSFRPEFINRIDETVVFHPLGEEHIKSIARIQLKSLMGRLESQGYEVEVSEALL
EKLVHAGFDPVYGARPLKRAIQHKVENPLAQALLSGRIVPGKKLVLGADSNGLTMTQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 5e-156 44
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 6e-107 42
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 1e-103 41
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 1e-103 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
AHML_21450 YP_008045393.1 ATP-dependent chaperone protein ClpB VFG0079 Protein 1e-142 44