Gene Information

Name : NH44784_041721 (NH44784_041721)
Accession : YP_008031237.1
Strain : Achromobacter xylosoxidans NH44784-1996
Genome accession: NC_021285
Putative virulence/resistance : Resistance
Product : Lead, cadmium, zinc and mercury transporting ATPase
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.5
Position : 4447403 - 4449559 bp
Length : 2157 bp
Strand : -
Note : -

DNA sequence :
ATGTCGGGCGGCGCGGCCGTGCTGCAGGCCGGCCCGGGCCAGTTGCTGGCGCGCCTGCGCATCGGCCAGATGGACTGCCC
CACCGAGGAAACGCTGATCCGCAAAAAGCTCGACGGCGTCGCCGGCGTGCACGCGCTGGACTTCAACCTGATGCAACGCA
TCCTGACCGTGGTGCACGCAGAGGGCGCGCTGGACCGCATCACGGCGGCCATCAAGTCGCTGGGCATGACGCCCGAGCCT
TTGACCGACGACACGCCGCGCACGCCGGCCCCGGCCGCCGCGCCCGTGAACTGGTGGGCCATCGGCGGCGCCGGCGTGCT
TGCCGCGCTGTCGGAAGCGTCGCACTTTGCCGGCATGCACTGGGGCGTCACCGCCGCGCTGGCGGTGGCCGCCATCCTGG
CCTGCGGCATCAGCACCTACCGCAAGGGCTGGATCGCCGTGCGCAACGGCAACCTGAACATCAACGCGCTGATGAGCATC
GCCGTCACCGGCGCGGTGCTGATCGGCCAGTGGCCGGAAGCGGCCATGGTGATGTTCCTGTTCAACGTGGCCGAACTGAT
CGAGGCCCGTTCGCTGGACCGCGCCCGCAACGCCATCCGCGGCCTGCTCGACCTGGCGCCCGAAACCGCCACCGTGCGCC
AGGCCGACGGCGGCTGGCAATCGGTGCCGGCGGCGCAACTGCAGATCGACGATGTGGTGCGGGTGCGACCGGGCGAACGC
ATCGCCGCCGACGGCATCATCGTCAGCGGCCGTTCGGCGGTGGACCAGTCCCCCATCACCGGCGAAAGCCTGCCGGTGGA
AAAGGCCGAGGGCGACCCGGTCTACGCGGCCACCGTCAACGCGGCCGGCTCGTTCGACTACCGCGTCACCGCGGCGGCGG
GCAACACCACGCTGGCGCGCATCATCCACGCGGTCGAACAGGCCCAGGGCGCGCGCGCGCCAACCCAGCGCTTCATCGAC
CGTTTCTCGCGCATCTACACGCCCGCCGTGGTCGGCGTGGCGCTGCTGGTGGCAGTGCTGCCGCCGCTGCTGTGGGCGCA
GCCCTGGTTCGACGCGATCTACCGCGCGCTGGCGCTGCTGATCATCGCCTGCCCCTGCGCCCTGGTGATCTCCACGCCGG
TCAGCATCGTCAGCGGCCTGACGGCGGCCTCGCGCCGCGGCATCCTGGTCAAGGGCGGCGTGTACCTGGAGGAAGGCCGC
AACCTGAAGTGGCTGGCGCTGGACAAGACCGGCACGCTGACCCATGGCAAGCCGGTGCAGACCGACCTGCAGGACTGGGC
CGTCTCCGACCTGGCGCGCCAGCCCGCGGCGCAGATTGCCGCCAGCCTGGCGGCGCGCTCGGACCACCCGGTGTCGCTGG
CCGTGGCCAACGCCGCGCGCGACGCCGGCCAGGCCCTGCTGGACGTGGACGACTTCACCGCCCTGCCCGGCCGCGGCGTC
AGCGGCAAGGTGGACGGCGTGCTGTTCCAGTTGGGCAACCGCCGCCTGATGCGCGAGCTGGGCGTGTCGGACGAAAAGCT
GGAAGCCCGCTTCGACGAACTGGAACAGCAGGGCAAGAGCGCTATCGCGCTCAGCGATGGCCAGCGCGTGCTGGCGCTGG
CGGCGGTGGCCGACACGGTCAAGCCCACCAGCGCGGCCGCCATCGCCGACCTGCACGCGCTGGGCGTGCGCACCCTGATG
CTGACGGGCGACAACACGCCCACGGCGCAAGCCATCGCGCGCCAGGTCGGCATCGACGAAGCGCGCGGCGATCAACTTCC
GGAAGACAAGCTGGCCGCCATCGAAAGCAAGCTGGCGCCCGCCGGCAAGGTCGGCATGGTCGGCGACGGCATCAACGACG
CCCCCGCCCTGGCCCGCGCCGATATCGGCTTCGCCATGGGCGCGGCCGGCACCGGCACCGCCATCGAAACGGCCGACGTG
GCGCTGATGGACGACGACCTGCGCAAGATCGGCACCTTCCTGCGCCTGTCGCGCGCCACCCACCGCGTGCTGGTGCAGAA
CATCGCGCTGGCGCTCGGCATCAAGGTGGTGTTCCTGGCGCTGGCGATGACCGGCAACGCCACGCTGTGGATGGCGGTGT
TCGCCGACGTCGGCGCCAGCCTGCTGGTGGTGGCCAACGGCTTGCGGCTGCTGCGGGCCGCCCCGGCGGCGAACTGA

Protein sequence :
MSGGAAVLQAGPGQLLARLRIGQMDCPTEETLIRKKLDGVAGVHALDFNLMQRILTVVHAEGALDRITAAIKSLGMTPEP
LTDDTPRTPAPAAAPVNWWAIGGAGVLAALSEASHFAGMHWGVTAALAVAAILACGISTYRKGWIAVRNGNLNINALMSI
AVTGAVLIGQWPEAAMVMFLFNVAELIEARSLDRARNAIRGLLDLAPETATVRQADGGWQSVPAAQLQIDDVVRVRPGER
IAADGIIVSGRSAVDQSPITGESLPVEKAEGDPVYAATVNAAGSFDYRVTAAAGNTTLARIIHAVEQAQGARAPTQRFID
RFSRIYTPAVVGVALLVAVLPPLLWAQPWFDAIYRALALLIIACPCALVISTPVSIVSGLTAASRRGILVKGGVYLEEGR
NLKWLALDKTGTLTHGKPVQTDLQDWAVSDLARQPAAQIAASLAARSDHPVSLAVANAARDAGQALLDVDDFTALPGRGV
SGKVDGVLFQLGNRRLMRELGVSDEKLEARFDELEQQGKSAIALSDGQRVLALAAVADTVKPTSAAAIADLHALGVRTLM
LTGDNTPTAQAIARQVGIDEARGDQLPEDKLAAIESKLAPAGKVGMVGDGINDAPALARADIGFAMGAAGTGTAIETADV
ALMDDDLRKIGTFLRLSRATHRVLVQNIALALGIKVVFLALAMTGNATLWMAVFADVGASLLVVANGLRLLRAAPAAN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 0.0 67
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 8e-96 45
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 8e-96 45
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 7e-94 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
NH44784_041721 YP_008031237.1 Lead, cadmium, zinc and mercury transporting ATPase BAC0298 Protein 1e-177 66
NH44784_041721 YP_008031237.1 Lead, cadmium, zinc and mercury transporting ATPase BAC0461 Protein 2e-64 42