Gene Information

Name : NH44784_014751 (NH44784_014751)
Accession : YP_008028570.1
Strain : Achromobacter xylosoxidans NH44784-1996
Genome accession: NC_021285
Putative virulence/resistance : Virulence
Product : Type III secretion inner membrane channel protein (LcrD,HrcV,EscV,SsaV
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1552395 - 1554488 bp
Length : 2094 bp
Strand : +
Note : -

DNA sequence :
ATGCAAGCCCTGAACCGCGTCGTCGCCGCCGCCACCAGCCGCAACGATATCGTCCTGGCGGTCCTGATCGTCTCGATCAT
CTTCATGATGATCCTGCCGCTGCCCACGACGCTGGTCGACGTGCTGATCGGCGCCAACATGACGCTGTCGGCCATCCTGC
TGATGGTGGCCATGTACCTGCCATCGCCGCTGGCGTTCTCGTCGTTCCCGTCGGTGCTGCTGGTCACCACGCTGTTCCGC
CTGGGCATCTCGATCGCCACCACCCGCCTGATCCTGCTGCAGGGCGATGCCGGCCACATCATCGAGACCTTCGGCAACTT
CGTGGTGGGCGGCAATCTCATTGTCGGCCTGGTGGTGTTCCTGATCCTCACCATCGTGCAATTCGTGGTCATCACCAAGG
GCGCCGAGCGCGTGGCCGAAGTAGCGGCGCGCTTCTCGCTGGACGCCATGCCCGGCAAGCAGATGTCGATCGACGCCGAC
CTGCGCGCCGGCACCATCGACATGGACGAGGCGCGCAAGCGCCGCTCGGTGGTGGAAAAGGAAAGCCAGCTGTACGGCGC
CATGGACGGCGCCATGAAATTCGTCAAGGGCGACGCCATCGCCGGACTCATCATCGTCGCGGTCAACCTGCTGGGCGGCA
TCCTCATCGGCACCATGCAGCGCGGCCTGTCCGCCGGCGAGGCGGTGCAGGTGTACTCGATCCTGACCATCGGCGACGGC
CTGATCGCGCAAATCCCGGCGCTGTTCATCGCCATCTGCGCCGGCATCATCGTGACCCGGGTGCAGACCGGCGACGGCCC
CTCCAACGTCGGCAAGGACATCGGCGCCCAGGTGCTGGCGCAACCGCGCGCGCTCTTGATCGCCGCCGCCATCGCGATCG
GCATGGGCCTGATCCCGGGCATGCCGACCCTGACCTTCCTGGCGCTGGCCGCGGTGGTCGGCACCATCGGCTTCGTGCTG
CTGCGCGGCACGCGCAAGGTGGTGGACGAGAAGACCGGCGAGATCACCGAAATCCCCGCCCTGGCGGCCGATGGCCAGAA
GCCGCAGGCCAGGCCGCGCGCCGACGGCAGCGCCGAGTTCGCGCCCACCCTGCCGCTGATGATCGACGTGGCCGCCGCGC
TGCAACGCAGCTTCGACGCCGACGAGCTCAACGAAGAACTGCTGAAGATCCGCCGCGCGCTCTATTTCGACCTGGGCGTG
CCGTTCCCCGGCATCCAGCTGCGCTTCAACGACGCGCTGCCGGCGGACAGCTACAACATCCTGCTGTCCGAAGTGCCGGT
CTCCCAGGGCAAGCTGCGGCCGGGCGCGGTGCTGGTGCGCGACACGGAACAGAACCTGCAGGCGCTGCAGGTGCCCTACG
AAACCGACAAGCGCTTCCTGCCCAACGTCCCGACGCTCTGGGTCGACGCCGGCCTGGCGCCCACCTTGACGGCCGCCGGC
ATCCCGTTCCTGGACCCGCACCAGGTGCTGACCTGGCACCTGGCCTTCGTGCTGAAGAAATACTCGTCGGACTTCATCGG
CATCCAGGAAACGCGCTTCCTGTTGACGGCCATGGAAGACCGCTTCCCCGACCTGGTCAAGGAAGCGCTGCGGGTGATGC
CGGTGCAGAAGATCGCCGAGATCCTGCAGCGGCTGGTGTCCGAGGACATCTCTGTGCGCAACCTGCGCGCGGTGCTGGAA
GCGCTGATCGAATGGGGACAGAAGGAAAAGGACTCGGTGCTGCTGACCGAATACGTGCGCGTCTCTCTCAAGCGCCACAT
CAGCTACAAGTACTCCAGCGGCCAGAACATCCTGCCGGCCTACCTGCTGGCGCCCAACGTCGAAGAAACCGTGCGCGGCG
CCATCCGCCAGACCTCGGCCGGCAGCTACCTGGCGCTCGACCCCAATGCCTCCAGGAAGCTGGTGGACAACATCAAGCGC
GTCGCCGGCGACCTGACGGCGGCAGCCCAGAAGCCCGTGCTGCTGACCTCGATGGACATCCGGCGCTACCTGCGCAAGAT
GATCGAGCAGGACCTGTACGAGCTGCCGGTGCTGTCCTACCAGGAGCTGACCCAGGAAATCAACGTGCAGCCGCTGGCCC
GGGTGGATCTGTGA

Protein sequence :
MQALNRVVAAATSRNDIVLAVLIVSIIFMMILPLPTTLVDVLIGANMTLSAILLMVAMYLPSPLAFSSFPSVLLVTTLFR
LGISIATTRLILLQGDAGHIIETFGNFVVGGNLIVGLVVFLILTIVQFVVITKGAERVAEVAARFSLDAMPGKQMSIDAD
LRAGTIDMDEARKRRSVVEKESQLYGAMDGAMKFVKGDAIAGLIIVAVNLLGGILIGTMQRGLSAGEAVQVYSILTIGDG
LIAQIPALFIAICAGIIVTRVQTGDGPSNVGKDIGAQVLAQPRALLIAAAIAIGMGLIPGMPTLTFLALAAVVGTIGFVL
LRGTRKVVDEKTGEITEIPALAADGQKPQARPRADGSAEFAPTLPLMIDVAAALQRSFDADELNEELLKIRRALYFDLGV
PFPGIQLRFNDALPADSYNILLSEVPVSQGKLRPGAVLVRDTEQNLQALQVPYETDKRFLPNVPTLWVDAGLAPTLTAAG
IPFLDPHQVLTWHLAFVLKKYSSDFIGIQETRFLLTAMEDRFPDLVKEALRVMPVQKIAEILQRLVSEDISVRNLRAVLE
ALIEWGQKEKDSVLLTEYVRVSLKRHISYKYSSGQNILPAYLLAPNVEETVRGAIRQTSAGSYLALDPNASRKLVDNIKR
VAGDLTAAAQKPVLLTSMDIRRYLRKMIEQDLYELPVLSYQELTQEINVQPLARVDL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lssD AAO18050.1 LssD Virulence TTSS locus Protein 0.0 59
YPO0266 YP_002345347.1 secretion system apparatus protein SsaV Virulence Not named Protein 8e-118 47
hrcV ABA47273.1 HrcV Virulence S-PAI Protein 2e-104 45
hrcV YP_362156.1 HrcV protein Virulence Hrp PAI Protein 2e-100 44
hrcV AAT96297.1 HrcV Virulence S-PAI Protein 7e-103 44
hrcV AAT96337.1 HrcV Virulence S-PAI Protein 3e-103 44
hrcV AAT96256.1 HrcV Virulence S-PAI Protein 2e-103 44
hrcV AAT96139.1 HrcV Virulence T-PAI Protein 2e-105 44
hrcV AAT96193.1 HrcV Virulence T-PAI Protein 1e-105 44
escV CAI43875.1 EscV protein Virulence LEE Protein 9e-101 43
escV YP_003223476.1 translocator EscV Virulence LEE Protein 1e-100 43
hrcV BAB07859.1 HrcV Virulence Hrp PAI Protein 1e-99 43
hrcV YP_198723.1 protein HrcV Virulence Hrp PAI Protein 2e-99 43
hrpI AAA03015.1 HrpI Virulence Hrp PAI Protein 7e-105 43
hrcV ABQ88352.1 HrcV Virulence Hrp PAI Protein 7e-105 43
hrcV NP_791229.1 type III secretion protein HrcV Virulence Hrp PAI Protein 1e-103 43
ysaV AAS66840.1 YsaV Not tested SSR-1 Protein 5e-99 43
invA NP_806499.1 virulence-associated secretory protein Virulence SPI-1 Protein 5e-100 43
invA NP_461817.1 needle complex export protein Virulence SPI-1 Protein 5e-100 43
hrcV AAG33877.1 HrcV Virulence Hrp PAI Protein 2e-103 43
invA YP_217815.1 invasion protein Virulence SPI-1 Protein 5e-100 43
invA NP_457290.1 possible secretory protein (associated with virulence) Virulence SPI-1 Protein 5e-100 43
escV AFO66296.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 2e-99 43
escV AFO66414.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 3e-99 43
unnamed AAL06368.1 EscV Virulence LEE Protein 1e-100 42
escV AAC38382.1 EscV Virulence LEE Protein 2e-101 42
escV NP_290269.1 hypothetical protein Virulence LEE Protein 1e-100 42
ECs4569 NP_312596.1 hypothetical protein Virulence LEE Protein 1e-100 42
escV YP_003236089.1 putative translocator EscV Virulence LEE Protein 6e-100 42
escV AAC31514.1 L0035 Virulence LEE Protein 1e-100 42
escV ACU09459.1 EscV protein Virulence LEE Protein 1e-100 42
hrcV AAP34346.1 HrcV Virulence Hrp PAI Protein 8e-87 42
XC_3013 YP_244081.1 HrcV protein Virulence Hrp PAI Protein 4e-89 42
hrcV NP_636603.1 protein HrcV Virulence Hrp PAI Protein 4e-89 42
escV CAC81861.1 EscV protein Virulence LEE II Protein 2e-100 42
escV YP_003232152.1 T3SS structure protein EscV Virulence LEE Protein 2e-100 42
escV AAK26714.1 EscV Virulence LEE Protein 2e-100 42
escV AAL57541.1 EscV Virulence LEE Protein 2e-100 42
hrcV NP_640760.1 HrcV protein Virulence Hrp PAI Protein 7e-87 42
ssaV NP_456114.1 putative type III secretion protein Virulence SPI-2 Protein 1e-98 42
ssaV NP_805085.1 secretion system apparatus protein SsaV Virulence SPI-2 Protein 1e-98 42
ssaV YP_216422.1 secretion system apparatus protein SsaV Virulence SPI-2 Protein 6e-99 42
ssaV NP_460379.1 secretion system apparatus protein SsaV Virulence SPI-2 Protein 5e-99 42
ssaV CAA70536.1 secretion system apparatus Virulence SPI-2 Protein 4e-99 42
ECs3731 NP_311758.1 EivA Not tested LIM Protein 4e-103 42
invA AAS66860.1 InvA Not tested SSR-2 Protein 1e-90 42
hrcV AAR25631.1 type III secretion protein HrcV Not tested Not named Protein 2e-98 42
hrcV AAB05999.2 HrcV Virulence Hrp PAI Protein 3e-106 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
NH44784_014751 YP_008028570.1 Type III secretion inner membrane channel protein (LcrD,HrcV,EscV,SsaV VFG0064 Protein 0.0 81
NH44784_014751 YP_008028570.1 Type III secretion inner membrane channel protein (LcrD,HrcV,EscV,SsaV VFG0198 Protein 3e-172 58
NH44784_014751 YP_008028570.1 Type III secretion inner membrane channel protein (LcrD,HrcV,EscV,SsaV VFG0384 Protein 0.0 57
NH44784_014751 YP_008028570.1 Type III secretion inner membrane channel protein (LcrD,HrcV,EscV,SsaV VFG2126 Protein 4e-135 47
NH44784_014751 YP_008028570.1 Type III secretion inner membrane channel protein (LcrD,HrcV,EscV,SsaV VFG0557 Protein 2e-100 43
NH44784_014751 YP_008028570.1 Type III secretion inner membrane channel protein (LcrD,HrcV,EscV,SsaV VFG0729 Protein 1e-101 42
NH44784_014751 YP_008028570.1 Type III secretion inner membrane channel protein (LcrD,HrcV,EscV,SsaV VFG0813 Protein 6e-101 42
NH44784_014751 YP_008028570.1 Type III secretion inner membrane channel protein (LcrD,HrcV,EscV,SsaV VFG0514 Protein 2e-99 42
NH44784_014751 YP_008028570.1 Type III secretion inner membrane channel protein (LcrD,HrcV,EscV,SsaV VFG1006 Protein 1e-97 41