Gene Information

Name : MASS_4814 (MASS_4814)
Accession : YP_008025280.1
Strain : Mycobacterium abscessus 50594
Genome accession: NC_021282
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4861725 - 4863209 bp
Length : 1485 bp
Strand : -
Note : -

DNA sequence :
ATGTCCACGTCCCAGTATGCTCCGGACCGCAGCTACGGAATGTTCATCGACAACCAATGGGTGGACGCGGAGTCCGGGGA
GACGATCGAGAGTATCAATCCCGCGACGGGTGAGGTGCTGACTCGTATTCCTAGTGGAACAGCCGCTGATGTCGATCGCG
CGGTCCAGGCGGCGCAGCGTGCGTTTGCGGGCTGGAGGGCGACCACGGTGACGGAACGGGCGAACGCGTTGAACAGGATC
GCCGACCTGCTGGAGGCTGACGCCGAGCGTTTCGCGGTCCTGGAGTCGCTGGATGTGGGCAAGCCGATTCGCGAGTCGCG
CGTTCTCGACGTGCCCATCGCCATTGATCACTTCAGGTACTTCGCCGGAGTGATTCGCAGTCACTCAGACGAGGCGGCCG
TGCTTGATGAACAGACCCTCAGCCTCGTGCTGAGCGAACCGCTTGGTGTGGTTGGTCAGGTGATCCCCTGGAACTTTCCG
TTGTTGATGGCAGCCTGGAAGATTGCCCCGGCAATCGCCACAGGGAACACCGTGGTGATCAAGCCATCGGAGATGACGCC
GGTCAGCATTTCCGAACTGGCAAAGATTTTCGCGCAAGTTCTTCCCCCCGGTGTCGTCAACATCGTCACCGGCACAGGGC
CGGTTGCCGGCCAGGCCGTGCTGGATCACCCGACGGTACAGAAGCTGGCATTCACCGGTTCCACCCGAGTCGGCTACACC
GTCGCCGAAGCCGCAGCCAAAAGACTGGTACCAGCAACGCTGGAGCTGGGCGGCAAATCGGCGAATATCGTTTTCCCCGA
CGCGAATTGGGACAAGGCCGTCGAGGGGGCAGCCCTGGCGATTCTATGGAATCAAGGCCAAGCCTGCGAATCCGGAGCTC
GCCTCTTCATTCACGAGTCGATCTACGACCGTTTTATCGACGAACTAAAAGCCAAGTTCACCACGGCCCGCGTGGGGGAT
CCCCTCTCACCAGACACCCAGGTGGGCTCGTTGATCAGCAAAGCCCAGCTGGAGCGCGTGTTGGGCTATGTAGAAACCGG
TCGTGCTGAAGGTGCCACGGTTTTGACGGGTGGTCGCCGGCTCACTGGCGGGGACTACGATTCCGGATTCTTTGTCGAGC
CGACAATATTGGTCGATGTGCGCAACGATATGCGCGTTGCATCGGAAGAGATCTTCGGCCCCGTTCTCGTTGTTATCCCA
TTCAAGGACGAGGATGAAGTTATCGCCTTGGCCAACGACTCAGAATACGGACTCGCCGGCACAGTGTGGACCCAAGACAT
CAACCGTGCACTTCGCGTGGCACGCGCGGTGGAGACCGGTCGGATGTGGGTGAACACGGCCCATGAGATCCCTGCGCATG
CACCCTTCGGGGGCTACAAGAAATCCGGTCTGGGCCGCGAAGCCTACAAATCCATGCTTGACGCGTACACCCACAAGAAG
AACATCTACGTGAGCATGAACGAAGCTCCGCGCGGACTGTTCTAA

Protein sequence :
MSTSQYAPDRSYGMFIDNQWVDAESGETIESINPATGEVLTRIPSGTAADVDRAVQAAQRAFAGWRATTVTERANALNRI
ADLLEADAERFAVLESLDVGKPIRESRVLDVPIAIDHFRYFAGVIRSHSDEAAVLDEQTLSLVLSEPLGVVGQVIPWNFP
LLMAAWKIAPAIATGNTVVIKPSEMTPVSISELAKIFAQVLPPGVVNIVTGTGPVAGQAVLDHPTVQKLAFTGSTRVGYT
VAEAAAKRLVPATLELGGKSANIVFPDANWDKAVEGAALAILWNQGQACESGARLFIHESIYDRFIDELKAKFTTARVGD
PLSPDTQVGSLISKAQLERVLGYVETGRAEGATVLTGGRRLTGGDYDSGFFVEPTILVDVRNDMRVASEEIFGPVLVVIP
FKDEDEVIALANDSEYGLAGTVWTQDINRALRVARAVETGRMWVNTAHEIPAHAPFGGYKKSGLGREAYKSMLDAYTHKK
NIYVSMNEAPRGLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-104 48
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 4e-108 48
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 4e-108 48
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 4e-108 48
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-108 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MASS_4814 YP_008025280.1 aldehyde dehydrogenase VFG0082 Protein 9e-105 48