Gene Information

Name : MASS_2303 (MASS_2303)
Accession : YP_008022769.1
Strain : Mycobacterium abscessus 50594
Genome accession: NC_021282
Putative virulence/resistance : Resistance
Product : streptomycin 3''-kinase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2369290 - 2370069 bp
Length : 780 bp
Strand : +
Note : -

DNA sequence :
GTGGACGGGCGTTTGATCGATCTGTCGGCCTGGGAGCCGATCGTGACGGGGGAGTCCGGTGCCTCCGTGTACCGCTCGCC
CGACGGTTCTCGCTATGCGAAAGAAGGCGGTGCCGATCTTGCGGGCGAGCGGGACCGCATCGAATGGCTTAGTGCTCAAC
GTATCCCGGGCCCGTCGGTGCTCGAGTGGGCGACCACGCCGGACGGCCCGCTGCTGATCACCTCGGCGGTACCGGGCGTA
CCCGCCGACCAGCTCGACTCCGAGGGTTTGGGCAGGGCATGGTCTGCCATCGCCGCAGCGGTGCGGGACCTGCACGCGCT
GCCGACAGCGGGCTGTCCGTTTTCGCGGGAACTGGCCGCCATGGCAACGTTGGCCCGCGACGTCGTGGCCCGCGACGCCG
TGAACCCGGATTTCCTGCCCGACGAAGACCGGGCGAGGCCCGCGACCGAGCTGCTATGCCGTGTTGTGGCCGAACTGCCT
CAGCGGCTGGGCCAGGAGGCGGGAGACCTGGTGGTGTGCCATGGGGACTTGTGCCTGCCGAATATCGTCATCGCGCCCGG
AGACTTCTCGGTGGCAGGTTTCATCGATCTCGGCCGGCTCGGGTTGGCCGACCGGCACGCCGATCTGGCCCTGCTCTTCG
CCAATGCCCGGGAGACCTGGCCCGGGGACGGCTGGGTCGCGGCCGCCGCCCACGAGCGGTTCCTGAACCGGTACGGAGCG
CCTGCCGACCCCGAACGGTTGGCGTTCTACCTGCGGTTGGATCCGCTGACCTGGGGATAG

Protein sequence :
MDGRLIDLSAWEPIVTGESGASVYRSPDGSRYAKEGGADLAGERDRIEWLSAQRIPGPSVLEWATTPDGPLLITSAVPGV
PADQLDSEGLGRAWSAIAAAVRDLHALPTAGCPFSRELAAMATLARDVVARDAVNPDFLPDEDRARPATELLCRVVAELP
QRLGQEAGDLVVCHGDLCLPNIVIAPGDFSVAGFIDLGRLGLADRHADLALLFANARETWPGDGWVAAAAHERFLNRYGA
PADPERLAFYLRLDPLTWG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
strA YP_005176180.1 aminoglycoside 3''-phosphotransferase protein Not tested ICEPmu1 Protein 1e-52 48
strA AEA34675.1 aminoglycoside phosphotransferase Not tested Not named Protein 1e-53 48
strA AFH57207.1 streptomycin resistance protein Not tested AbaR4a Protein 1e-53 48
strA AGK07031.1 StrA streptomycin phosphotransferase Not tested SGI1 Protein 1e-53 48
strA AGK07089.1 StrA streptomycin phosphotransferase Not tested SGI1 Protein 1e-53 48
strA AFV47972.1 streptomycin (3') phosphotransferase StrA Not tested AbaR25 Protein 1e-53 48
strA YP_001800932.1 aminoglycoside-3''-phosphotransferase Not tested Not named Protein 1e-53 48
strA AFV48000.1 streptomycin (3') phosphotransferase StrA Not tested delta-AbaR25 Protein 1e-53 48
strA AEQ20909.1 StrA, APH(3')-Ib streptomycin(3') phosphotransferase Not tested Tn6166 Protein 1e-53 48
strA AEZ06049.1 StrA, APH(3')-Ib, streptomycin(3') phosphotransferase Not tested Tn6167 Protein 1e-53 48
strA ACK44539.1 StrA Not tested SGI1 Protein 1e-53 48
strA CAJ77025.1 Streptomycin phosphotransferase A Not tested AbaR1 Protein 7e-54 48
ABK1_0266 YP_005512838.1 StrA Not tested AbaR4d Protein 1e-53 48
BJAB07104_00282 YP_008207747.1 Aminoglycoside phosphotransferase Not tested AbaR25 Protein 1e-53 48
ABZJ_00266 YP_005524222.1 hypothetical protein Not tested AbaR22 Protein 1e-53 48
BJAB0868_00286 YP_008211612.1 Aminoglycoside phosphotransferase Not tested AbaR26 Protein 6e-53 48
ABK1_0258 YP_005512830.1 StrA Not tested AbaR4d Protein 2e-53 48

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MASS_2303 YP_008022769.1 streptomycin 3''-kinase DQ336355.1.orf1.gene Protein 2e-55 55
MASS_2303 YP_008022769.1 streptomycin 3''-kinase AF024602.1.gene5.p01 Protein 6e-54 48
MASS_2303 YP_008022769.1 streptomycin 3''-kinase K00432.1.orf2.gene.p Protein 1e-31 43