Gene Information

Name : lysS (MASS_2245)
Accession : YP_008022711.1
Strain : Mycobacterium abscessus 50594
Genome accession: NC_021282
Putative virulence/resistance : Unknown
Product : lysine--tRNA ligase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2307753 - 2311085 bp
Length : 3333 bp
Strand : -
Note : -

DNA sequence :
GTGACATCCATCAAACCGGCAGTTGAACCACCCGCCCCGGATCATTCCGCTGTCACGGTGCTTCCGGGAATCGGTGCACG
CCCGGCAGCGCGACCACCCGTGACCTCACGGTGGCGCTGGGTCCCGGCGTTCTTCGGCTGGTTTGTCGGCATCCAGGCGA
TCCTGAACTTCCTGTCGAGCATTTCGCCATTCATTCGGATGGTGACGAAGCTGCCTCGCGAGTTCGTCGACGAATATCTG
TTCGGTTGGCCCGACGGCAGCCTGTCCTGGGCTTTTGTGCTGTCGCTACTGGCCGCCGCCCTGGCGGTGCGCAAGAGCAT
CGCCTGGTGGGTGCTCTTGATCGACCTACTGGGACGGTCAGCACTGAACGTGGGCGGCTTCATAGAGCATCGCGATACCA
CCGAGCTGATCGGTCTCGTCGTGCACGGCGCGTTCATCCTGTTGCTGCTGCTCGCGCGTAAGGAGTTCTACGCCAAGGTA
CGGCGCGGCGCGACGGTCAAGGCGGCGCTGGTGCTGATCGCGGGGATGGCCGCCGGGACAGTCCTGGCATGGGGCCTGCT
GGAGCTCTTTCCCCGCACGCTTGTCCCCGGTGATCGTTTCTGGTGGGCACTCAATCGGGTGGCCGGCTTTTCGATCGCCT
CACACCGCGATTTCGACGGTCTGCCCCCTCACTTCCTGAACTGGCTCTTCGGGCTATTCGGCGCGCTGGCCCTGATCGCC
GCGGCCATCGTGTTGTTCCGCTCGCAACGAGCCGTCAACGCGCTGACCGGTGATGACGAATCTCTGATCCGCGGACTCCT
GGAGCGTTATGGGCAGGACGACTCCCTGGGGTATTTCGCGACGAGACGCGACAAGGCGGTCATCTTCGCACCCAATGGCC
GAGCGGCTGTGACATATCGGGTGGAAGTCGGCGTCTGTCTGGTCAGTGCCGATCCCATTGGGGACAAATCGGCTTGGGGC
CAAGCTATTTCCGCATGGCTGCAGGTGTGCGACGCGTACGGCTGGGCGCCGGCGGTCATGGGCGCCAGCGCCGAAGGTGC
GCTGGCGTATCGCGAGCATGGGCTCAACGCACTGGAACTCGGCGACGAGGCCATCCTGTACCCGCGCTCATTCTCGATTT
CGGGCCCGCACATGGCCGCGGTCCGGCAGGCGGTCAACCGCGCCCGACGTTCGGGACTCTCGGTGCGTATCCGCCGCCAT
CGCGAACTGAGCGCCGAAGACACGAAACAGATCATCGTCAATGCCGACCTGTGGCGTGATGGCAATACCGAGCGCGGCTT
CTCGATGGCGCTGGGACGGTTGGGGGATTCCACCGACGGCGACTGCCTGTTGGTTGAGGCGATCGATTCCACGGGCGATC
CCGTCGCCATGCTGTCTCTCGTACCTTGGGGCACTAACGGGGTGTCCCTCGAGCTCATGCGCCGCTCGCGTCAATCACCC
AACGGCACTATCGAATTCATGGTCACGGAGCTGCTCACACGCGCAGAGGGCATGGGGATCACCCGCGTTTCCCTCAACTT
TGTGATGTTCCGCTCGGTCTACGCCGACGGCTCCCGAATCGGAGCGGGCCCGGTGCTACGACTGTGGCGCTCGGTGCTGA
TGTTCGCCTCACGGTTCTGGCAGTTCGAGCAGTTGTATCGCTCCAATGTGAAGTATCAGCCGGAATGGGTGCCCCGGTTC
GCCTGCTACGAGGACGCCCGGCTCATCCCCCGCATCGGCATCGCGTCGGTGATCGCCGAAGGCTTCCTGGTGCTGCCCTT
CGGCAACCGCGACAAGCCGAGGCACACCGGCCAGTACAGCGCGGTTCCGCAGGCCATCGTGGCCACGGGCCTGCTGCATC
ACGATGGCAGCACACCCGAGCTACTGCCCCAAACGGCACCTCAACAGCGCGTACCGGAGCAGGTCAAGGTTCGACTGGGC
AAGCTGGCTGCCTTACAGGAGAAGGGAATCGACGCGTACCCGGTGGGATCGCCACCGTCCCATACCGTCGCCGAGGCCCT
TGCCGCACCCGACGGTAGCGAAGTGGTGATCAGCGGGCGCTTGTTGCGAATCCGCGACTACGGCGGTGTGTTGTTCGCAC
AGCTACGGGATTGGTCCGCAGAGGTGCAGCTGCTTATCGACGATCCGCGGCTACACGAAGAGTTCACCGCCGCCGTCGAT
CTGGGTGACCTGGTCGAGGCCAGCGGGGTCATGGGTCAATCGAACAACGGCACCCGATCAGTCTTGGTGAAGTCGTGGCG
GATCATCGGCAAATGCCTGCACCCGCTCCCCGATAAGCGTAAGGGCCTTACCGACCCCGAAGCCAGGGTGCGTGCACGAT
ACCTCGACCTGGCGATCAACCCCGAGGCTCGCGAGCAGATCGCGGCCCGTAGCGCGATCATCACATCGCTGCGCAATACC
CTTTTGGCTCAAGACTTCCTAGAGGTGGAAACACCAATCCTGCAGCAGGTGCACGGCGGAGCCAACGCGCGTCCCTTCCT
GACGCACATCAACGCGTACAACCTGGATCTGTATCTGCGTATCGCCCCGGAGCTGTACCTCAAGCGGCTCTGCGTCGGTG
GCGTGGAGAAGGTCTTCGAATTGGGCCGGGCCTTCCGCAACGAGGGCGTGGACTTCAGCCATAATCCCGAATTCACCCTG
CTCGAGGCCTATCAGGCACACGCCGACTATGTGACTTGGGCCAAGACCACACAGCGGCTCATCCAGAACGCCGCGAAAGC
CGCCCACGGGGCCGAAGTAGTGATGCGGCCCGGTGTCGACGGGAGGCTGGCACCGGTGGACATCGGTGGCGAATGGCCAA
TCGTCCCGGTGCATGAGGCGGTCTCTCACGCGCTGGGTGAAGAGGTCAACGCTGCGACGGAAGTGCCGGCACTGCGAAGG
TTCTGCCAGTCCGCGGAGGTGCAGTTCAATCCGCGCTGGGATGCCGGCCACCTGGTCCTGGAACTCTACGAACGGCTGGT
GGAGAAACACACGACCTCACCCACGTTCTATAGCGATTTCCCGGTCTCGGTATCGCCGCTTACCCGCCCGCACCGCAGCA
TCACCGGGCTCGCCGAGCGCTGGGACCTGGTCGCGTGGGGTGTCGAACTCGGCACCGCCTATACCGAGCTGACCGACCCG
GTGGAACAGCGCCGACGCCTGTATGAGCAATCACTGCTGGCGGCCGGCGGAGACGCCGAAGCGATGGAACTCGACGAGGA
TTTCCTGCGCGCGATGGAGTACGCAATGGCGCCGACCGGCGGGATGGGCATGGGAGTGGACCGGGTGGTCATGCTGATCA
CCGGGCGCAGCATCCGCGAAACACTGCCCTTCCCGCTGGCCAAGCCCCGCTAG

Protein sequence :
MTSIKPAVEPPAPDHSAVTVLPGIGARPAARPPVTSRWRWVPAFFGWFVGIQAILNFLSSISPFIRMVTKLPREFVDEYL
FGWPDGSLSWAFVLSLLAAALAVRKSIAWWVLLIDLLGRSALNVGGFIEHRDTTELIGLVVHGAFILLLLLARKEFYAKV
RRGATVKAALVLIAGMAAGTVLAWGLLELFPRTLVPGDRFWWALNRVAGFSIASHRDFDGLPPHFLNWLFGLFGALALIA
AAIVLFRSQRAVNALTGDDESLIRGLLERYGQDDSLGYFATRRDKAVIFAPNGRAAVTYRVEVGVCLVSADPIGDKSAWG
QAISAWLQVCDAYGWAPAVMGASAEGALAYREHGLNALELGDEAILYPRSFSISGPHMAAVRQAVNRARRSGLSVRIRRH
RELSAEDTKQIIVNADLWRDGNTERGFSMALGRLGDSTDGDCLLVEAIDSTGDPVAMLSLVPWGTNGVSLELMRRSRQSP
NGTIEFMVTELLTRAEGMGITRVSLNFVMFRSVYADGSRIGAGPVLRLWRSVLMFASRFWQFEQLYRSNVKYQPEWVPRF
ACYEDARLIPRIGIASVIAEGFLVLPFGNRDKPRHTGQYSAVPQAIVATGLLHHDGSTPELLPQTAPQQRVPEQVKVRLG
KLAALQEKGIDAYPVGSPPSHTVAEALAAPDGSEVVISGRLLRIRDYGGVLFAQLRDWSAEVQLLIDDPRLHEEFTAAVD
LGDLVEASGVMGQSNNGTRSVLVKSWRIIGKCLHPLPDKRKGLTDPEARVRARYLDLAINPEAREQIAARSAIITSLRNT
LLAQDFLEVETPILQQVHGGANARPFLTHINAYNLDLYLRIAPELYLKRLCVGGVEKVFELGRAFRNEGVDFSHNPEFTL
LEAYQAHADYVTWAKTTQRLIQNAAKAAHGAEVVMRPGVDGRLAPVDIGGEWPIVPVHEAVSHALGEEVNAATEVPALRR
FCQSAEVQFNPRWDAGHLVLELYERLVEKHTTSPTFYSDFPVSVSPLTRPHRSITGLAERWDLVAWGVELGTAYTELTDP
VEQRRRLYEQSLLAAGGDAEAMELDEDFLRAMEYAMAPTGGMGMGVDRVVMLITGRSIRETLPFPLAKPR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lysS1 YP_005682181.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 3e-145 41
lysS1 YP_005684273.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 2e-145 41
lysX YP_003784331.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 2e-145 41
lysS1 YP_005686365.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 2e-145 41