Gene Information

Name : metB (AORI_6927)
Accession : YP_008015912.1
Strain : Amycolatopsis orientalis HCCB10007
Genome accession: NC_021252
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 7742058 - 7743215 bp
Length : 1158 bp
Strand : -
Note : -

DNA sequence :
ATGGCCGACGATTACTCTCTGCTGGGCTTCGAGACGCGCGCGATCCACGCCGGGCAGACCCCTGATCCCCGGACCGGCGC
GGTCATCGTGCCGATCTACCAGACCTCGACTTACGCGCAGGACGGCGTCGGCGGCACGCGCGAAGGCGACTACGAGTACT
CCCGCACCGCGAACCCCACGCGCACCGCGCTGGAGGTCGCGCTGGCGGCGCTCGAAGGCGCGCGGCACGGTCTGGCGTAC
GCGTCGGGGATGGCGGCGAGTGACGTCCTGCTGCGGGCGACCCTGCGGCCGGGAGACCACCTCGTGCTCGGCAACGACGC
GTACGGCGGCACGTTCCGGCTGATCGACAAGGTGCTCAGCCTGTGGGGTGTCGAGCACACGGTCGCCGACCTGGGGAACA
TCGCCGAGGTCCGGGCGGCGATCCGGCCGGAGACGAAGCTGATCTGGTGCGAGTCGCCGACGAACCCGATGCTCGGAATC
GCCGACATCGCCGCGCTGGCCGAGGTCGCGCACGGTGCCGGTGCGCGACTGGTCGTCGACAACACCTTCGCCACCCCGTA
CCTGCAGAACCCGCTTTCGCTTGGTGCCGACGTCGTCCTGCACTCGACGACCAAGTACCTCGGCGGGCACTCCGACGTCG
TCGGCGGCGCGATCCTGACGAACGAGGACGAACTGCGCGAGCAGCTGTTCTACCTGCGCAACGCGGCGGGTGCGGTGCCC
GGCCCGTTCGACGCGTGGCTGACCCTGCGCGGGATCAAGACGCTCGCGCTGCGGATGGAGCGGCACAGCGACAACGCCGA
ACTGATCGCCCGGATGCTGCTGAAGCACCCGAAGGTCGAGCGTGTCTACTACCCGGGCCTGCCGGAGCACCCCGGACACG
AGGTCGCTTCGAAGCAGATGCGCCGCTTCGGCGGGATGATCTCGTTCACCCACGTCGACGGCGAGCAGGCCGCCCTCGAG
GCCGCGTCGAAGACGAAGCTGTTCATCCTCGCCGAGTCTCTGGGCGGCATCGAGTCGCTGATCGAGCACCCGGGCCGGAT
GACCCACGCGAGCACCGCCGGGTCGACCCTGGAGGTGCCGGACAACCTGCTGCGCCTGTCCGTCGGCATCGAGGACGGCA
GCGACCTGGTCGCCGATCTGGCCCAGGCTCTGGGCTGA

Protein sequence :
MADDYSLLGFETRAIHAGQTPDPRTGAVIVPIYQTSTYAQDGVGGTREGDYEYSRTANPTRTALEVALAALEGARHGLAY
ASGMAASDVLLRATLRPGDHLVLGNDAYGGTFRLIDKVLSLWGVEHTVADLGNIAEVRAAIRPETKLIWCESPTNPMLGI
ADIAALAEVAHGAGARLVVDNTFATPYLQNPLSLGADVVLHSTTKYLGGHSDVVGGAILTNEDELREQLFYLRNAAGAVP
GPFDAWLTLRGIKTLALRMERHSDNAELIARMLLKHPKVERVYYPGLPEHPGHEVASKQMRRFGGMISFTHVDGEQAALE
AASKTKLFILAESLGGIESLIEHPGRMTHASTAGSTLEVPDNLLRLSVGIEDGSDLVADLAQALG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-72 49
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-73 49
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 3e-55 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_008015912.1 cystathionine gamma-synthase BAC0207 Protein 1e-59 45