Gene Information

Name : dhbE (AORI_6598)
Accession : YP_008015584.1
Strain : Amycolatopsis orientalis HCCB10007
Genome accession: NC_021252
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 7391304 - 7392974 bp
Length : 1671 bp
Strand : -
Note : -

DNA sequence :
GTGCCCTCGAAACCTGTCCAGCCGAGCCGCGCGGGGACGGTCCCCTGGCCCGCCGACCTCGTCGAGCGTTACGTCGCCGA
AGGGCACTGGAAGGGCCAGGCGCTCGCCTCGCGCTTCGTGGCCGCCGCCGACGCGACCCCGGACGCAGAGGCACTGACCG
ACGGCGGCTTCCGGCTGACGTACGCCGAACTCCTGTCCCGTGTGGACGGTGCCGCCCAGCGGCTGCGGGCGCTGGGACTC
CGGCCCGACGACCGGCTCCTGGTCCAGCTGCCCAACGGCTGGGAGTTCGTGGTGCTGACGCTGGCGTGCTTCCGGCTCGG
TGTCATCCCGGTGATGGCGCTGATCCAGCACCGCAGGCACGAACTGTCCTACCTTGCCGAGCTGTCCGAGGCGCGCGCGA
TCGCCGTGCCGGACCGGGTGAAGGACTTCGACCACCAGGAGCTGGCGGCCGGGATCGCCGCCGGGGCCGAGACCATCGAG
CACGTCATCGTCGCCGGTGACGTCCGCGACGGGCACGTGGACCTGCGTGCGCTGTGCGCCCCGGCTTCGGATCCGGCCGC
GGCGCGCGCCGAACTGGACGCGCTGACGCCCGACCCGCGATCGGTCGCGCTGCTGATCCTTTCCGGCGGCACGACGGGGC
TGCCGAAGCTCATCGCACGCACCCACGACGACTACGCCTGCTATGTCGACGGATCCGCCGACGCGTTCGGTTTCGACGCG
TCGTCGGTTTATCTCGCCGTGCTGCCGTTCGGGCACAACTACCCGCTGAGCGCGATCCTCGGCGTGCTGTGGGCAGGCGG
GCGCGTGGTCGTCTCGCCGTCGCCGTCCCCGCGGGACTCGCTGGGCGCGATCGAAGCCGAACGCGCGACCGTGACGTCGG
TGGTGCCGGCGATCGTGGTGCGCTGGCTCGAATACCGCGAGGCCGACAAGCAGCACGACCTGTCGTCGTTCAAGGTGCTG
ACGCTGGGCGCCGCGCGGTTGCAGGATCAGCTGGTCCGCCAGATCAGCACGGTGTTCGGCTGTACGCTGCAGCAGGGCTA
CGGGATGGCGGAGGGGCTGACCAACCTCACCCGGCTGGACGACCCGTTCGACATCACCTGCGACACCCAGGGCCGCCCGA
TCAACCCCGCCGACGAACTGCGCGTCGTCGACCCCGACGGTAACCCGGTCCCGCCGGACGAGCAGGGCGAGCTGATCACC
CGCGGCCCGTACACGATCCGCGGCTACTACCGCGCGCCCGAACACAACGAGCGCGCTTTCACCCCGGACGGGTGGTACCG
CACGGGTGACGTCGTGCGGCTGCGGCCGGACGGCTACGTCGTCGTCGAAGGGCGCACCAAGGACGTGATCAACCGCGGCG
GCGAGAAGATCGCGGCCGAGGAGGTCGAATCCTTCGCCTACCAGCTCGATTCGGTGGAGATGGCGGCCTCGGTCGCGATG
CCGGACCCGGTGCTCGGCGAGCGCGGCTGCCTCTACGTGGTGCCGACGCCCGGCACCTCCGTCGCCCTGCAGGACGTCAT
CGACGTCATGGAGACGGCGGGGGTCGCCCGGTTCAAACTCCCCGAACGGCTGGTGATCGTCGACGCGATGCCGCGCACCC
CGATCGGCAAGATCGACAAAAAGGTGCTGCGGGCGGACATCGCGCGACGGCTCGAAGAAGAAGCCGCCTGA

Protein sequence :
MPSKPVQPSRAGTVPWPADLVERYVAEGHWKGQALASRFVAAADATPDAEALTDGGFRLTYAELLSRVDGAAQRLRALGL
RPDDRLLVQLPNGWEFVVLTLACFRLGVIPVMALIQHRRHELSYLAELSEARAIAVPDRVKDFDHQELAAGIAAGAETIE
HVIVAGDVRDGHVDLRALCAPASDPAAARAELDALTPDPRSVALLILSGGTTGLPKLIARTHDDYACYVDGSADAFGFDA
SSVYLAVLPFGHNYPLSAILGVLWAGGRVVVSPSPSPRDSLGAIEAERATVTSVVPAIVVRWLEYREADKQHDLSSFKVL
TLGAARLQDQLVRQISTVFGCTLQQGYGMAEGLTNLTRLDDPFDITCDTQGRPINPADELRVVDPDGNPVPPDEQGELIT
RGPYTIRGYYRAPEHNERAFTPDGWYRTGDVVRLRPDGYVVVEGRTKDVINRGGEKIAAEEVESFAYQLDSVEMAASVAM
PDPVLGERGCLYVVPTPGTSVALQDVIDVMETAGVARFKLPERLVIVDAMPRTPIGKIDKKVLRADIARRLEEEAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-75 46
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-75 46
ybtE CAA21394.1 - Virulence HPI Protein 1e-75 46
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 7e-76 46
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 1e-75 46
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-75 46
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 1e-75 46
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 9e-76 45
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 7e-76 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
dhbE YP_008015584.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 8e-87 45
dhbE YP_008015584.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 1e-70 44