Gene Information

Name : dhbE (AORI_3539)
Accession : YP_008012527.1
Strain : Amycolatopsis orientalis HCCB10007
Genome accession: NC_021252
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3874181 - 3875803 bp
Length : 1623 bp
Strand : +
Note : -

DNA sequence : 
ATGACCGCCGATCACGTGCCGTGGCCACCGGAAACCGCGGCGCGCTACCGGGCTTCGGGGTACTGGCGCGGCCAGACCTT
CGGGAAGCTGCTGACCAGTCTCGCCGAGGCGTACGCCGAGCGCCTCGCCGTGATCGGCGAGAACGCCCGCTGGACGTTCG
CCGAACTCGACGAGCGCGCGCACCGGCTCGCCGCCGGATTCGCCGGGGCCGGGATCCAGGCCGGTGACCGGGTCGTCGTG
CAACTGCCGAACGTGCCGGAGTTCGCGTCCGTCGTGTTCGGACTGTGGCGGGCCGGTGCGCTGCCGGTGTTCGCGCTGCC
CGCGCACCGCGCGAGCGAACTGCGGCATTTCGCCGAGCAGAGCGAGGCCGCGGCGATCCTCACCGTCGGCGAACACGAAC
GGTTCGACCACGCGGCCATGGCGCGCGCGGTCGCGGCCGAGATCCCCTCGGTGCGCAACGTCTTCGTCGTCGGCACGGAG
GAATTCGCCGTCCTGGAAGCGGCGACTCCGCGCGCTCTGCCGGATCCCGATCCCGCCGGGGTCGCGTTCCTCCAGCTGTC
CGGGGGAAGCACCGGATTACCCAAGCTGATCCCGCGCACGCACGACGACTATCTCTACAGCGTCCGGGAAAGCTCCCGGA
TCTGCGGCCTGCGCCCGGAAAGCGTGTACCTGGCCGCGTTGCCGGTCGCGCACAACTTCCCGCTCAGCTCGCCCGGCCTG
CTCGGCGCGCTGCACGCGGGCGCGGCGACGGTGTTCGCGCCGCGGCCCGACGCCGACACCGCGTTCCGGCTCATCGAGGC
CGAAGGCGTGACGATCACCGGGCTCGTACCGCCGCTCGCCGCGGCGTGGGCGCAGGCGGCCGCGCGGACCGGGCGCGATC
TGTCCTCTTTGGACGTCCTGCTGGTCGGCGGCGCGAAATGCGCCCGTGAACTGGCCGAGAAGATCGGGCCCGCGCTGGGA
TGCCGTCTGCAGCAGGTGTTCGGCATGGCCGAAGGGCTGGTCTGCTACACCCGGCTCGACGACCCGGACGAGTACGTCCT
CGCCACACAGGGACGGCCGATTTCGCCGGACGACGAGATCCGCGTGGTGAACCCGGACGATCCACTGTCCACTTCGGACG
ACGTCGTCGCGCCGGGGGAGGTCGGCGCGCTGCTGACCCGCGGCCCGTACACGATCCGCGGCTATTACCGCGCCGAGGAG
CACAACAAGACCGCGTTCACCGAGGACGGTTTCTACCGCACCGGTGACCTCGTGCGGCGGCATCCGTCCGGGCATCTGGA
AGTGGTCGGCCGGGCCAAGGAACAGATCAACCGCGGTGGCGAGAAGGTGGCCGCTGAGGAGGTCGAGAACCACCTGATGG
CCCACCCCGGCGTGCTCGACGCCGCCGTCGTCGCGGTGCCGGACCCGTACCTGGGCGAGCGCACCTGCGCCTACGTCGTC
CCGGCCGCCGGTGCCGAACCCGCGGCGGCGGAGCTGCGCCGGTTCGTCCGGGAACGCGGGGTCGCGGCGTTCAAGGTGCC
CGATCTGGTCCAGGTGGTGCCGGAGTTCCCGGTGACCGGGGTCGGCAAGACCAGCAAACGCGAGCTGCGGGCGGCGCTGG
CCGCTCTGGCGAAGGAGAAGTGA

Protein sequence : 
MTADHVPWPPETAARYRASGYWRGQTFGKLLTSLAEAYAERLAVIGENARWTFAELDERAHRLAAGFAGAGIQAGDRVVV
QLPNVPEFASVVFGLWRAGALPVFALPAHRASELRHFAEQSEAAAILTVGEHERFDHAAMARAVAAEIPSVRNVFVVGTE
EFAVLEAATPRALPDPDPAGVAFLQLSGGSTGLPKLIPRTHDDYLYSVRESSRICGLRPESVYLAALPVAHNFPLSSPGL
LGALHAGAATVFAPRPDADTAFRLIEAEGVTITGLVPPLAAAWAQAAARTGRDLSSLDVLLVGGAKCARELAEKIGPALG
CRLQQVFGMAEGLVCYTRLDDPDEYVLATQGRPISPDDEIRVVNPDDPLSTSDDVVAPGEVGALLTRGPYTIRGYYRAEE
HNKTAFTEDGFYRTGDLVRRHPSGHLEVVGRAKEQINRGGEKVAAEEVENHLMAHPGVLDAAVVAVPDPYLGERTCAYVV
PAAGAEPAAAELRRFVRERGVAAFKVPDLVQVVPEFPVTGVGKTSKRELRAALAALAKEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 9e-87 47
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 9e-87 47
ybtE CAA21394.1 - Virulence HPI Protein 9e-87 47
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 7e-87 47
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 8e-88 47
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 7e-87 47
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 6e-88 47
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 9e-87 47
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 9e-87 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
dhbE YP_008012527.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 8e-100 50
dhbE YP_008012527.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 3e-91 48
dhbE YP_008012527.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 5e-87 44