Gene Information

Name : ddl (AORI_1472)
Accession : YP_008010463.1
Strain : Amycolatopsis orientalis HCCB10007
Genome accession: NC_021252
Putative virulence/resistance : Resistance
Product : D-alanine-D-alanine ligase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1534151 - 1535197 bp
Length : 1047 bp
Strand : +
Note : -

DNA sequence :
ATGGGTAGGCTGAAAATCGGAATTCTGTTCGGCGGGCTTTCCGAAGAACATCCTATCTCCATCAAATCTGCGCGTGAGGT
CCAGAAGCACCTCGACCTCGAGAAGTACGAGCCGTACTACATCGGGATCACCCAGAGCGGTTCCTGGATGCTGTGCGACG
GCCCCGCCGAGGACTGGGAGAACGGCGACGTCCGCCCGGCCGTCCTGTCGCCGGACCGCGGTGTGCACGGCCTGCTCGTC
CTGGACGAGGGCAAGTACGAGACGATCGCCCTCGACGTGGTGCTGCCGGTGCTGCACGGCAAGTTCGGCGAAGACGGCGC
GATGCAGGGCCTGCTGGAGATCTCCGGCATCCCCTACGTCGGCTGCGACCTCCCGAGCTCGGTCATGTGCATCGACAAGT
CGCTCACCTATTCGGTCGTCCGCGGCGCGGGGATCGCGACGCCGACCTTCCACATCGTCACGCCGGACAACGACGTCGAC
CCGGACGCGCTGAACTACCCGGTCTTCGTGAAGCCCGCCCGCTCCGGCTCGTCGTTCGGCGTCAGCAAGGTCTCCTCGAA
GGAAGAGCTGCCCGCCGCGCTGGCGGAGGCGCGCCAGTACGACGCGAAGATCCTGATCGAAGAGGCCGTTATCGGCAGTG
AGATCGGCTGCTCGATCCTCGGCGACGGCGAGGACCTGTTCGCGGGTGAGGTCGACCGGGTCGCGCTGACCCACGGCTTC
TTCAAGATCCACCAGGAGAAGAGCCCCGAGACCGGTTCCGAGAACTCGAGCTTCATCGTCCCCGCCGACATCCCGGACGC
CTCGCGTGACCTGGTCCAGGAGACGGCCAAGGTCATCTACCGTGCGCTGGGCTGCAGCGGGCTCGCGCGCGTGGACCTGT
TCCTCAAGGAGGACGGCAGTGTCGTGCTCAACGAGGTCAACACCCTGCCCGGCCTGACCTCGTACAGCCGTTACCCGCGG
ATGATGAACGCCGCCGGCCTCTCGCTCGGCGACGTGATCGACCGCCTGGTGAAGCTGACGCTGGCGGGCGTGACGAATGA
GGGATGA

Protein sequence :
MGRLKIGILFGGLSEEHPISIKSAREVQKHLDLEKYEPYYIGITQSGSWMLCDGPAEDWENGDVRPAVLSPDRGVHGLLV
LDEGKYETIALDVVLPVLHGKFGEDGAMQGLLEISGIPYVGCDLPSSVMCIDKSLTYSVVRGAGIATPTFHIVTPDNDVD
PDALNYPVFVKPARSGSSFGVSKVSSKEELPAALAEARQYDAKILIEEAVIGSEIGCSILGDGEDLFAGEVDRVALTHGF
FKIHQEKSPETGSENSSFIVPADIPDASRDLVQETAKVIYRALGCSGLARVDLFLKEDGSVVLNEVNTLPGLTSYSRYPR
MMNAAGLSLGDVIDRLVKLTLAGVTNEG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
vanB YP_008394259.1 Vancomycin B-type resistance protein vanB, D-alanine--D-lactate ligase Not tested Not named Protein 6e-101 61
vanB NP_815951.1 D-alanine--D-lactate ligase Not tested Not named Protein 1e-98 60

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ddl YP_008010463.1 D-alanine-D-alanine ligase AF277571.gene.p01 Protein 3e-107 65
ddl YP_008010463.1 D-alanine-D-alanine ligase AY489045.gene.p01 Protein 1e-103 63
ddl YP_008010463.1 D-alanine-D-alanine ligase AF130997.1.orf4.gene Protein 3e-105 62
ddl YP_008010463.1 D-alanine-D-alanine ligase AY145441.gene.p01 Protein 3e-100 61
ddl YP_008010463.1 D-alanine-D-alanine ligase AF310956.2.orf5.gene Protein 2e-100 61
ddl YP_008010463.1 D-alanine-D-alanine ligase U00456.gene.p01 Protein 5e-99 60
ddl YP_008010463.1 D-alanine-D-alanine ligase U35369.1.gene6.p01 Protein 5e-99 60
ddl YP_008010463.1 D-alanine-D-alanine ligase AE016830.1.gene2250. Protein 5e-99 60
ddl YP_008010463.1 D-alanine-D-alanine ligase NC_014475.1.orf3.gen Protein 8e-97 59
ddl YP_008010463.1 D-alanine-D-alanine ligase NC_005054.2598280.p0 Protein 8e-97 59