Gene Information

Name : ldhA (AORI_1471)
Accession : YP_008010462.1
Strain : Amycolatopsis orientalis HCCB10007
Genome accession: NC_021252
Putative virulence/resistance : Resistance
Product : D-lactate dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1533274 - 1534149 bp
Length : 876 bp
Strand : +
Note : -

DNA sequence :
ATGCCGACCATTGTGGACGAGCCGGTATCCGAGGCGAATATCGGGCTGGTCTCCGGAAATCGATGCATCAGTATCGGTCA
CAAGACCAAGGTCACGAATTCCATTCTTCTCGCCCTCGCCGAAGCGGGCGTGGAATACATCTCCACCAGGAGCATCGGCT
TCAACCACATCGATGTGGAATACGCGGCGAGCGTCGGTATCACCGTGGGCAATGTCGCCTACTCGCCCGACAGCGTCGCC
GACTTCACGCTGATGCTGATGCTGATGGCGGTGCGCGACGCCAAGTCCATCATCCGCCGCACCGAGGTGCACGACTACCG
GCTGAACGAGGTGCGCGGGAAAGAGCTGCGCGATCTGACCGTCGGAGTGGTCGGAACAGGGCGGATCGGGGTCGCGGTGC
TGGACCGGCTGCGTGGTTTCGGCTGCCGGGTGCTGGCCTACGACACGCTGCTGACCGCCTCGGCCGATTACGTTCCGCTC
GACGAATTGCTCCAGCAGAGCGACATCGTGACGCTCCATGTGCCGCTCAACAACGATACCTATCATCTTCTCGACCGGAA
GAACATCGAGCGGATGAAGGACGGCGCGTACATCATCAACACCGGACGTGGCCCGCTCATCGAAACCGAAGCCCTCATTT
CGGCACTGGAAGACGGCAAACTGGGCGGAGCGGCATTGGACGTCGTCGAAGGAGAGGAAGGCATCTTCTACGCCGACTGC
CGGAACAAGCCGCTCGAGAGCGAAACGTTGCTGCGGCTGGAAAAGCTGCCGAACGTGCTCATCAGTCCGCATACCGCCTA
TTACACGGACCACGCACTGAGTGACACTGTTGAAAACTCCATCATCAATTGTCTCCAATTCGAAAGCGGGAAGTAG

Protein sequence :
MPTIVDEPVSEANIGLVSGNRCISIGHKTKVTNSILLALAEAGVEYISTRSIGFNHIDVEYAASVGITVGNVAYSPDSVA
DFTLMLMLMAVRDAKSIIRRTEVHDYRLNEVRGKELRDLTVGVVGTGRIGVAVLDRLRGFGCRVLAYDTLLTASADYVPL
DELLQQSDIVTLHVPLNNDTYHLLDRKNIERMKDGAYIINTGRGPLIETEALISALEDGKLGGAALDVVEGEEGIFYADC
RNKPLESETLLRLEKLPNVLISPHTAYYTDHALSDTVENSIINCLQFESGK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF2295 NP_815952.1 D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 7e-80 60
vanHB YP_008394258.1 VanH protein, D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 1e-78 58

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ldhA YP_008010462.1 D-lactate dehydrogenase AF155139.2.orf4.gene Protein 1e-88 65
ldhA YP_008010462.1 D-lactate dehydrogenase NC_014475.1.orf2.gen Protein 3e-85 64
ldhA YP_008010462.1 D-lactate dehydrogenase NC_005054.2598279.p0 Protein 3e-85 64
ldhA YP_008010462.1 D-lactate dehydrogenase FJ349556.1.orf3.gene Protein 2e-85 62
ldhA YP_008010462.1 D-lactate dehydrogenase U35369.1.gene5.p01 Protein 7e-80 60
ldhA YP_008010462.1 D-lactate dehydrogenase AF310956.2.orf4.gene Protein 2e-79 59
ldhA YP_008010462.1 D-lactate dehydrogenase AF130997.1.orf3.gene Protein 2e-75 58