Gene Information

Name : iucA (KPR_4897)
Accession : YP_007993871.1
Strain : Klebsiella pneumoniae SB3432
Genome accession: NC_021232
Putative virulence/resistance : Virulence
Product : hypothetical protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 5011556 - 5013343 bp
Length : 1788 bp
Strand : -
Note : highly similar to aerobactin siderophore biosynthesis protein IucA from Escherichia coli (sp|Q47316)

DNA sequence :
TTGATAATGAGAAGCTTTATTGACAAAATTCTCATTATTATTACGAGTGAGATCTGTTTGACTATGACTTTGCCAACTAA
AACCTCAACCTTGGATGTGGCTGCGCAGTGCTTCCTTAATTCCCTGGTTCGTGAAACCAAAGACTGGCGGCTGACGGAAT
ACCAGCCAACCCAATTGATCATCCCGCTGGGCGAACAGCAGGCGCTCCATTTCAGAGTGGCTTATTTCTCCCCAACCCAG
CATCACCGCTTTGAATTTCCGGCGCGTCTGGTCACGGCATCCGGCAGTCACCCCATCGATTTCACCACCCTCTCCCGGCT
TATTGTTGATAAGCTCCAGCACCAACTCTTGCTGCCCGCGACCAGTTGCGAAACCTTCCACCAGCGCGTGATGGAAAGCC
ACGCCCATACGCAGCAGGCGATTGATGCCCGCCATGACTGGGCAGCCCTGCGTGAAAAAGCGTTGAACTTTGGCGAGGCG
GAACAGGCTCTGCTGGTCGGGCACGCCTTCCACCCGGCGCCTAAGTCTCATGAACCGTTTAACCAGCAGGAGGCCGAACG
CTACCTGCCGGACTTCGCGCCCCACTTCCCGCTGCGATGGTTTGCGGTGGACAAAACGCAGATCGCCGGTGAAAGCCTGC
ATCTCAACCTGCAACAGCGGTTGACGCGATTTGCCGCAGAGAATGCGCCGCAGTTACTCAATGAATTAAGCGACAATCAA
TGGCTATTCCCGCTGCACCCGTGGCAGGGGGAGTATCTGTTGCGACAGGAGTGGTGCCAGGAGCTTGTCGCTAAAGGGCT
GATTAAAGATTTAGGCGAAGCCGGCGCGCCGTGGCTACCGACCACCTCTTCCCGCTCGCTCTACTGCGCCACCAGCCGTG
ATATGATCAAATTCTCCCTGAGCGTGCGCCTGACCAACTCCGTCCGAACCCTGTCAGTGAAAGAAGTGAAGCGTGGAATG
CGCCTAGCGCGCCTGGCGCAAACCGACGACTGGCAGACGCTACAGGCCCGCTTCCCAACTTTCCGGGTGATGCAGGAAGA
CGGCTGGGCCGGGCTACGCGATCTCCACGGCAACATCATGCAGGAAAGCCTGTTTGCCCTGCGTGAAAACCTACTGGTGA
ATCAGCCGCAAAGCCAGACTAACGTACTGGTCTCCCTGACCCAGTCTGCACCGGATGGCGGTGATTCGCTGCTGGTTGCG
GCGGTAAAACGCCTGAGCGATCGCCTCGGCATCACTGCGCAACAGGCCGCTCACGCATGGGTCGATGCTTACTGTCAGCA
GGTGCTGAAACCGCTGTTTACGGCTGAAGCGGATTACGGCCTGGTGCTGCTGGCGCATCAGCAAAATATTCTGGTTCAGA
TGCTTGGGGATCTGCCGGTCGGGCTTATCTACCGTGACTGTCAGGGCAGCGCGTTTATGCCTCACGCGGCAGGCTGGCTC
GACACCATTGGCGAAGTTCAGGCGGAAAACGTCTTCACCCATGAGCAGTTGCTGCGCTACTTCCCTTATTACCTGCTGGT
TAACTCCACTTTTGCCGTGACCGCCGCGCTGGGCGCTGCCGGGCTGGACAGTGAAGCGAATCTGATGGCTCGCGTACGAA
CATTGCTGGCTGAAGTGCGTGATCAGGTGACTCATAAAACCTGTCTCAACTACGTGCTGGAAAATCCGTACTGGAACGTA
AAAGGTAACTTTTTCTGTTATCTGAACGACCACAACGAGAACACCATCGTCGATCCCTCGGTGATCTACTTCGATTTCGC
CAACCCACTGCTGGCTCAGGAGGGCTAA

Protein sequence :
MIMRSFIDKILIIITSEICLTMTLPTKTSTLDVAAQCFLNSLVRETKDWRLTEYQPTQLIIPLGEQQALHFRVAYFSPTQ
HHRFEFPARLVTASGSHPIDFTTLSRLIVDKLQHQLLLPATSCETFHQRVMESHAHTQQAIDARHDWAALREKALNFGEA
EQALLVGHAFHPAPKSHEPFNQQEAERYLPDFAPHFPLRWFAVDKTQIAGESLHLNLQQRLTRFAAENAPQLLNELSDNQ
WLFPLHPWQGEYLLRQEWCQELVAKGLIKDLGEAGAPWLPTTSSRSLYCATSRDMIKFSLSVRLTNSVRTLSVKEVKRGM
RLARLAQTDDWQTLQARFPTFRVMQEDGWAGLRDLHGNIMQESLFALRENLLVNQPQSQTNVLVSLTQSAPDGGDSLLVA
AVKRLSDRLGITAQQAAHAWVDAYCQQVLKPLFTAEADYGLVLLAHQQNILVQMLGDLPVGLIYRDCQGSAFMPHAAGWL
DTIGEVQAENVFTHEQLLRYFPYYLLVNSTFAVTAALGAAGLDSEANLMARVRTLLAEVRDQVTHKTCLNYVLENPYWNV
KGNFFCYLNDHNENTIVDPSVIYFDFANPLLAQEG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iucA AAD44746.1 IucA Virulence SHI-2 Protein 0.0 90
iucA NP_839223.1 siderophore biosynthesis protein Virulence SHI-2 Protein 0.0 90
iucA NP_709454.2 siderophore biosynthesis protein Virulence SHI-2 Protein 0.0 90
iucA YP_002414046.1 aerobactin siderophore biosynthesis protein Virulence Not named Protein 0.0 90
iucA AAK71631.1 IucA Virulence SHI-3 Protein 0.0 84

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
iucA YP_007993871.1 hypothetical protein VFG0615 Protein 0.0 90
iucA YP_007993871.1 hypothetical protein VFG0940 Protein 0.0 90
iucA YP_007993871.1 hypothetical protein VFG1081 Protein 0.0 84