Gene Information

Name : arsB (KPR_1724)
Accession : YP_007990705.1
Strain : Klebsiella pneumoniae SB3432
Genome accession: NC_021232
Putative virulence/resistance : Resistance
Product : hypothetical protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1816051 - 1817337 bp
Length : 1287 bp
Strand : +
Note : highly similar to arsenic efflux pump protein from Escherichia coli B354 (tr|D6JGF1)

DNA sequence :
ATGTTGCTGGCAGGTACGATTTTTATCCTGACCCTGGTGCTGGTGATCTGGCAGCCGCGGGGGTTAGGGATCGGCTGGAG
CGCGGCATTTGGCGCGGCGCTGGCGCTGGCCACCGGTGGCGTACAGGTAGCCGATATCCCGGTGGTATGGCATATCGTCT
GGAATGCGACCGCCACCTTTATCGCCGTTATCATTATCAGCCTGCTGCTTGATGAGTCTGGCTTTTTCGAATGGGCCGCG
CTGCACGTTTCCCGCTGGGGAAGAGGCCGGGGTCGTCTGCTGTTTACCTGGATTATCCTGCTCGGCGCGGCGGTGGCGGC
GCTGTTTGCCAACGATGGGGCGGCGCTGATCCTCACGCCAATCGTGATTGCCATGCTGCGAGCGCTGGGGTTCAGCAAGG
GAACGATGCTGGCCTTTGTCATGGCCGCCGGATTTATTGCCGATACCGCCAGCCTGCCGCTGGTGGTGTCGAATCTGGTG
AATATCGTTTCGGCAGATTTCTTTGCCATCGGCTTCAGGGAGTACGCTTCGGTGATGGTGCCGGTCGATCTCGCGGCGAT
CCTCACCACCCTGGCGATGCTGCACCTGTTCTTTCGCAAGGATATCCCGCCGGCCTGGGATATGGCGTTACTGAAAGCAC
CGGCCACGGCAATAAAAGATCCAGCGACGTTCCGCACCGGCTGGGGCGTGCTGTTGCTGGCTGGCTTTTTCATCCTTGAA
CCGCTGGGGATCCCGGTCAGCGCCATCGCGGCGCTCGGTGCCGGGATCCTGTTTGCTGTCGCGAAGCGCGGGCGGGTAAT
TAACACCGGCAAGGTGCTGCGCGGCGCCCCGTGGCAGATAGTGATCTTCTCGCTGGGAATGTATCTGGTGGTGTATGGTC
TGCGAAACGCCGGGTTAACGGATTATCTGACCACGGTGCTGAACATGCTGGCGGAGCGCGGCCTCTGGGCCGCGACGCTG
GGCACTGGTGTTCTGTCGGCCTTCCTCTCTTCGATTATGAATAATATGCCCAGCGTACTGGTCGGCGCCCTGTCGATTGA
AGGCAGCACGGCATCAGCGGCTATCAAAGAGGCTATGATATATGCCAACGTCATCGGTTGCGATCTGGGGCCGAAAATAA
CGCCAATTGGTAGCCTGGCCACGCTGCTCTGGCTGCATGTGCTGGCGCAAAAGCACATCACCATCGGTTGGGGTTATTAT
TTTCGCTGCGGCATTATCATGACCCTGCCGGTACTGCTCGTGACGCTGGCCGCGCTGGCGCTGCGTCTCTCCTTCAACCA
GCCATGA

Protein sequence :
MLLAGTIFILTLVLVIWQPRGLGIGWSAAFGAALALATGGVQVADIPVVWHIVWNATATFIAVIIISLLLDESGFFEWAA
LHVSRWGRGRGRLLFTWIILLGAAVAALFANDGAALILTPIVIAMLRALGFSKGTMLAFVMAAGFIADTASLPLVVSNLV
NIVSADFFAIGFREYASVMVPVDLAAILTTLAMLHLFFRKDIPPAWDMALLKAPATAIKDPATFRTGWGVLLLAGFFILE
PLGIPVSAIAALGAGILFAVAKRGRVINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTDYLTTVLNMLAERGLWAATL
GTGVLSAFLSSIMNNMPSVLVGALSIEGSTASAAIKEAMIYANVIGCDLGPKITPIGSLATLLWLHVLAQKHITIGWGYY
FRCGIIMTLPVLLVTLAALALRLSFNQP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsB2 YP_001007633.1 arsenical pump membrane protein Not tested YAPI Protein 5e-149 86
arsB YP_252017.1 arsenical pump membrane protein Not tested SCCmec Protein 2e-99 57
SH0109 YP_252024.1 arsenical pump membrane protein Not tested SCCmec Protein 2e-99 57
arsB YP_005754065.1 arsenical pump membrane protein Not tested Type-XI SCCmec Protein 1e-97 56

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
arsB YP_007990705.1 hypothetical protein BAC0578 Protein 4e-150 86
arsB YP_007990705.1 hypothetical protein BAC0576 Protein 3e-149 85
arsB YP_007990705.1 hypothetical protein BAC0031 Protein 1e-142 84
arsB YP_007990705.1 hypothetical protein BAC0577 Protein 1e-147 83
arsB YP_007990705.1 hypothetical protein BAC0575 Protein 1e-99 56
arsB YP_007990705.1 hypothetical protein BAC0574 Protein 1e-98 56