Gene Information

Name : guaA (KPR_1442)
Accession : YP_007990423.1
Strain : Klebsiella pneumoniae SB3432
Genome accession: NC_021232
Putative virulence/resistance : Unknown
Product : hypothetical protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1513523 - 1515100 bp
Length : 1578 bp
Strand : +
Note : highly similar to GMP synthase [glutamine-hydrolyzing] from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TCC2)

DNA sequence :
ATGACGGAAAACATTCATAAACATCGCATCCTCATCCTCGACTTCGGGTCTCAGTATACTCAGCTGGTGGCGCGTCGCGT
GCGTGAGCTGGGCGTCTACTGTGAGCTGTGGGCATGGGATGTCACGGAAGCACAGATCCGCGAATTTAATCCAAGCGGCA
TCATTCTTTCCGGCGGCCCGGAAAGCACCACCGAAGAGAACAGCCCGCGCGCGCCGCAGTATGTGTTCGAAGCCGGCGTG
CCGGTATTTGGCGTCTGCTACGGCATGCAGACCATGGCGATGCAGCTGGGCGGCCATGTAGAAGGTTCTAACGAGCGTGA
GTTTGGTTACGCGCAGGTTGAAGTGGTTAACGACAGCGCGCTGGTGCGCAGTATCGAAGATTCCCTGACCGCAGACGGCA
AACCGCTGCTGGACGTGTGGATGAGCCACGGCGACAAAGTGACCGCCATCCCGGCGGACTTCGTGACCGTCGCCAGCACC
GACAACTGCCCGTTCGCCATTATGGCCAACGAAGAAAAACGCTTCTACGGCGTGCAGTTCCACCCGGAAGTGACCCACAC
CCGTCAGGGGATGCGTATGCTGGAGCGCTTCGTGCGCGACATCTGCCAGTGCGAAGCGCTGTGGACCCCGGCGAAAATCA
TTGACGACGCCGTTGAGCGTATCCGTCAGCAGGTTGGCGACGACAAAGTGATCCTCGGCCTCTCCGGCGGTGTGGACTCT
TCGGTGACCGCGATGCTGCTGCACCGCGCTATCGGCAAAAACCTGACCTGTGTATTCGTGGACAACGGTCTGCTGCGCCT
GAACGAAGCGCAGCAGGTGATGGAGATGTTCGGCGACCACTTTGGCCTGAACATTGTTCACGTTGAAGGCGAGCAGCGTT
TCCTCGACGCGCTGGCGGGTGAAAGCGATCCGGAAGCGAAGCGTAAAATTATCGGTCGCGTTTTCGTGGAAGTGTTCGAC
GAAGAAGCGCTGAAGCTGGACGACGTCAAATGGCTGGCGCAGGGTACCATCTACCCTGACGTTATCGAGTCTGCCGCTTC
CGCCACCGGTAAAGCGCACGTCATCAAATCTCACCACAACGTGGGCGGCCTGCCGAAAGAGATGAAGATGGGCCTGGTTG
AGCCGCTGCGTGAGCTGTTCAAAGACGAAGTACGTAAGATCGGCCTGGAACTGGGCCTGCCGTACGACATGCTCTACCGT
CACCCGTTCCCGGGCCCCGGCCTTGGCGTGCGCGTGCTGGGCGAAGTGAAGAAAGAGTACTGCGACCTGCTGCGTCGTGC
GGACGCTATCTTCATCGAAGAGCTGCACAAAGCTGACCTGTATAACAAAGTCAGCCAGGCGTTCACTGTGTTCCTGCCGG
TTCGTTCCGTCGGCGTGATGGGCGATGGCCGTAAATACGACTGGGTCGTTTCCCTGCGTGCGGTGGAAACCATCGACTTT
ATGACCGCGCACTGGGCGCACCTGCCGTATGATTTCCTCGGCCGCGTCTCCAACCGTATCATCAATGAAGTGAACGGTAT
CTCCCGCGTGGTGTATGACATCAGCGGCAAGCCGCCAGCAACGATTGAGTGGGAATGA

Protein sequence :
MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIREFNPSGIILSGGPESTTEENSPRAPQYVFEAGV
PVFGVCYGMQTMAMQLGGHVEGSNEREFGYAQVEVVNDSALVRSIEDSLTADGKPLLDVWMSHGDKVTAIPADFVTVAST
DNCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAVERIRQQVGDDKVILGLSGGVDS
SVTAMLLHRAIGKNLTCVFVDNGLLRLNEAQQVMEMFGDHFGLNIVHVEGEQRFLDALAGESDPEAKRKIIGRVFVEVFD
EEALKLDDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLRELFKDEVRKIGLELGLPYDMLYR
HPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDF
MTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-127 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 6e-128 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 6e-128 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 6e-112 47