Gene Information

Name : sitC (KPR_1206)
Accession : YP_007990187.1
Strain : Klebsiella pneumoniae SB3432
Genome accession: NC_021232
Putative virulence/resistance : Virulence
Product : hypothetical protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1270429 - 1271277 bp
Length : 849 bp
Strand : -
Note : highly similar to iron transporter SitC from Salmonella enterica subsp. salamae (tr|B8Y8E9)

DNA sequence : 
ATGAGCTGGCTGCTGGAGCCGTTTGGCTATCACTATATGCTCAATGCGATGTGGGTGTCGGCGCTGGTGGGCGGCGTCTG
CGCCTTTCTCTCCTGCTACCTGATGCTCAAAGGCTGGTCGCTGATTGGCGACGCCCTCTCCCACTCGATTGTACCCGGCG
TCGCCGGGGCCTATATGCTCGGCCTGCCCTTCGCGCTCGGCGCGTTTCTCTCCGGCGGCCTGGCGGCGGGCAGCATGCTG
TTTTTGCAACAGCGCTCGCGGCTAAAAGAGGATGCCATTATCGGGCTGATCTTCTCCTCCTTCTTCGGGATCGGGCTGTT
TATGGTGTCGCTGAATCCGACGTCGGTGAATATCCAGACCATCATCCTCGGCAATATTCTGGCCATCGCCCCGGAGGATA
TTATCCAGCTGGCGGCGATCGGCTTTATCTCAATGGCGATTCTGCTGCTGAAGTGGAAAGACCTGATGGTGACCTTCTTT
GATGAACACCACGCCCGCTCGATTGGCCTGAACACCCGCGGCCTGAAGCTGCTGTTCTTTACCCTGCTGGCCGCCTGCAC
CGTGGCGGCGCTGCAGACCGTCGGCGCCTTTCTGGTCATCTGCCTGGTGGTCACTCCCGGGGCCACCGCGTGGCTGTTAA
CCGATCGCTTCCCGCGCCTGCTGGCCATCGCCGTGGCTATCGGCAGCCTGACCAGTTTCTTCGGCGCCTGGCTCAGCTAC
TATCTCGACGGCGCCACCGGCGGCATTATCGTGGTCGCGCAAACGCTGCTGTTCCTCATCACCTTTATCTTCGCGCCGAA
GCACGGCCTGCTGGCCAGCCGCCGCCGCGCCAGGGAGGCCGCATGCTGA

Protein sequence : 
MSWLLEPFGYHYMLNAMWVSALVGGVCAFLSCYLMLKGWSLIGDALSHSIVPGVAGAYMLGLPFALGAFLSGGLAAGSML
FLQQRSRLKEDAIIGLIFSSFFGIGLFMVSLNPTSVNIQTIILGNILAIAPEDIIQLAAIGFISMAILLLKWKDLMVTFF
DEHHARSIGLNTRGLKLLFFTLLAACTVAALQTVGAFLVICLVVTPGATAWLLTDRFPRLLAIAVAIGSLTSFFGAWLSY
YLDGATGGIIVVAQTLLFLITFIFAPKHGLLASRRRAREAAC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitC AAD41067.1 SitC Virulence centisome 63 pathogenicity island Protein 2e-83 88
sitC YP_217783.1 iron transporter: fur regulated Virulence SPI-1 Protein 3e-83 88
sitC NP_461784.1 permease Virulence SPI-1 Protein 3e-83 88
sitC NP_457257.1 Iron transport protein, inner membrane component Virulence SPI-1 Protein 2e-83 88
sitC NP_806466.1 iron transporter inner membrane protein Virulence SPI-1 Protein 2e-83 88
sitD AAD41068.1 SitD Virulence centisome 63 pathogenicity island Protein 1e-35 44
sitD NP_457258.1 Iron transport protein, inner membrane component Virulence SPI-1 Protein 3e-35 44
sitD NP_806467.1 iron transporter inner membrane protein Virulence SPI-1 Protein 3e-35 44
sitD YP_217784.1 iron transporter: fur regulated Virulence SPI-1 Protein 3e-35 44
sitD NP_461785.1 permease Virulence SPI-1 Protein 2e-35 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sitC YP_007990187.1 hypothetical protein BAC0351 Protein 1e-83 88
sitC YP_007990187.1 hypothetical protein BAC0441 Protein 4e-66 70
sitC YP_007990187.1 hypothetical protein BAC0352 Protein 9e-36 44
sitC YP_007990187.1 hypothetical protein BAC0442 Protein 3e-30 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sitC YP_007990187.1 hypothetical protein VFG0527 Protein 1e-83 88
sitC YP_007990187.1 hypothetical protein VFG0528 Protein 8e-36 44