Gene Information

Name : sitD (KPR_1205)
Accession : YP_007990186.1
Strain : Klebsiella pneumoniae SB3432
Genome accession: NC_021232
Putative virulence/resistance : Virulence
Product : hypothetical protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1269581 - 1270435 bp
Length : 855 bp
Strand : -
Note : similar to iron/manganese transport system membrane protein SitD from Escherichia coli strain SMS-3-5 - SECEC (tr|B1LE76)

DNA sequence :
ATGCTGAACCTGTTCCTGGCCCCGTTCCAGTTTCCTTTTATGGTCAATGCGATAGCGATATCGATCGTCGTCGCCATTCC
CTGCGCGCTGCTGTCGGTGTTTCTGGTGCTCAAAGGCTGGGCGCTGATGGGCGACGCCATGAGCCACGCGGTCTTTCCGG
GCGTGGTGCTGGCCTACATTATCGGCATCCCCTTCGCCATCGGCGCGTTTATCGCTGGTCTGCTGTGCGCCGTGACGACC
GGTTTTCTCGACGATAACAGCCGACTCAAGCGCGATACCATCATGGGGATTGTCTTCTCCGGCATGTTTGGCGCCGGACT
GGTGCTGTACGTAGCGATCCAGTCCGATGTTCATCTCGACCATATCCTGTTCGGCGATATGCTGGGAATATCCCTCCGCG
ATATTGGGCAAACGACGGCGATCGCACTGGTGATTGCGTTGATTATCGGTCTCAAATGGCGGGATTTTTTGCTGCACGCC
TTCGATCCAACGCAGGCTAAAGCCAGCGGCCTGCGCGGCGGACTGCTGCACTACGGCCTGCTGTGCATGATCGCCCTGAC
CATCGTCGCGACGCTGCAGTCGGTGGGGATTATTCTGTCGATTTCGCTGCTGATTGCCCCCGGGGCGATCGCGCTTCTGC
TGGTGAGACGCTTTATCCACGCCCTGCTGCTGGCGGTAGCGGTGGCCATCGGCTGCTCGGCGGGAGGGGTGTGGCTGGCG
TTTTATCTCGACAGCGCGCCAGCGCCGACTATCGTGGTGCTGTTTACCGCGCTGTTTGTAGTCGCCTTTGTCGCAAGCAC
GATCCGCGATAGTCAGAAACAGAAAACTTCAGCAATTATCCCCGGTGGCGGCTAA

Protein sequence :
MLNLFLAPFQFPFMVNAIAISIVVAIPCALLSVFLVLKGWALMGDAMSHAVFPGVVLAYIIGIPFAIGAFIAGLLCAVTT
GFLDDNSRLKRDTIMGIVFSGMFGAGLVLYVAIQSDVHLDHILFGDMLGISLRDIGQTTAIALVIALIIGLKWRDFLLHA
FDPTQAKASGLRGGLLHYGLLCMIALTIVATLQSVGIILSISLLIAPGAIALLLVRRFIHALLLAVAVAIGCSAGGVWLA
FYLDSAPAPTIVVLFTALFVVAFVASTIRDSQKQKTSAIIPGGG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitD NP_457258.1 Iron transport protein, inner membrane component Virulence SPI-1 Protein 5e-58 81
sitD NP_806467.1 iron transporter inner membrane protein Virulence SPI-1 Protein 5e-58 81
sitD NP_461785.1 permease Virulence SPI-1 Protein 5e-58 81
sitD YP_217784.1 iron transporter: fur regulated Virulence SPI-1 Protein 4e-58 81
sitD AAD41068.1 SitD Virulence centisome 63 pathogenicity island Protein 4e-58 81
sitC YP_217783.1 iron transporter: fur regulated Virulence SPI-1 Protein 2e-18 41
sitC NP_461784.1 permease Virulence SPI-1 Protein 2e-18 41
sitC AAD41067.1 SitC Virulence centisome 63 pathogenicity island Protein 1e-18 41
sitC NP_457257.1 Iron transport protein, inner membrane component Virulence SPI-1 Protein 2e-18 41
sitC NP_806466.1 iron transporter inner membrane protein Virulence SPI-1 Protein 2e-18 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sitD YP_007990186.1 hypothetical protein BAC0352 Protein 2e-58 81
sitD YP_007990186.1 hypothetical protein BAC0442 Protein 9e-38 52
sitD YP_007990186.1 hypothetical protein BAC0441 Protein 3e-21 43
sitD YP_007990186.1 hypothetical protein BAC0351 Protein 8e-19 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sitD YP_007990186.1 hypothetical protein VFG0528 Protein 2e-58 81
sitD YP_007990186.1 hypothetical protein VFG0527 Protein 7e-19 41