Gene Information

Name : glnA (K751_03180)
Accession : YP_007983616.1
Strain : Helicobacter pylori UM066
Genome accession: NC_021218
Putative virulence/resistance : Virulence
Product : glutamine synthetase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.1.2
Position : 1004099 - 1005544 bp
Length : 1446 bp
Strand : +
Note : forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltra

DNA sequence :
ATGGTAGTAAGAACTCAAAATAGTGAAAGCAAGATCAAAGAGTTTTTTGAATTTTGCAAAGAAAATGAAGTGGAATTTGT
GGATTTTAGATTCAGTGATATTAAAGGCACTTGGAATCACATCGCTTATTCTTTTGGGGCTTTAACGCATGGCATGTTTA
AAGAGGGGATTCCTTTTGATGCGAGTTCTTTTAAGGGCTGGCAAGGCATTGAACACTCCGATATGATTTTAACCCCTGAT
TTGGTGCGTTATTTCATTGACCCTTTTAGCGCGGATGTGAGCGTGGTCGTGTTTTGCGATGTGTATGATGTGTATAAAAA
CCAGCCTTATGAAAAATGCCCCAGAAGTATCGCTAAAAAAGCCTTACAACATTTAAAAGATTCAGGTTTGGGCGATGTGG
CTTATTTTGGTGCGGAGAATGAATTTTTCATCTTTGATTCCATTAAGATTAAAGACGCTTCCAATTCCCAATATTACGAA
GTGGATAGCGAAGAGGGCGAATGGAATAGGGATAGAAGTTTTGAAAATGGCGTGAATTTTGGGCATAGACCGGGCAAGCA
AGGGGGCTATATGCCTGTGCCACCAACAGATACGATGATGGATATTCGCACAGAAATTGTGAAAGTCTTAAACCAAGTGG
GGTTAGAAACTTTTGTCGTCCATCATGAAGTCGCGCAAGCGCAAGGCGAAGTGGGCGTGAAATTTGGGGATTTAGTGGAA
GCCGCTGACAATGTCCAAAAACTCAAATATGTGGTTAAAATGGTCGCTCATTTAAACGGCAAAACCGCCACTTTCATGCC
AAAACCTTTATATGGGGATAACGGGAGCGGGATGCACACCCATGTGAGTGTTTGGAAAAACAACGAAAACCTTTTTAGCG
GCGAAACTTACAAGGGCTTGAGCGAGTTGGCGTTGCATTTTTTAGGGGGCGTGTTGCGTCACGCTAGAGGGTTAGCCGCT
TTCACTAACGCTTCCACTAATTCTTACAAACGCCTAATTCCAGGTTATGAAGCTCCATCTATTTTAACCTATTCGGCTAA
CAATAGGAGCGCGAGCGTGCGTATCCCTTATGGGATTTCTAAAAACAGTGCGAGGTTTGAATTCAGGTTTCCTGATAGCT
CATCAAACCCCTACTTGGCTTTTGCAGCGATTTTAATGGCGGGTATGGATGGCGTTAAAAATAAGATCGATCCCGGCGAA
GCGATGGATATTAACCTTTTCAAATTGACTTTAGATGAAATCAGAGAAAAGGGTATCAAACAAATGCCCCACACTTTAAG
GAGATCGTTAGAAGAAATGCTAGCCGATAAGCAGTATTTAAAAGAAGGCCAGGTCTTTAGCGAAGAATTTATTCAAGCTT
ATCAGTCTCTTAAATTCAACGCTGAAGTGTTCCCATGGGAGAGCAAACCCCATCCTTTTGAATTTATCACCACTTATTCA
TGCTAA

Protein sequence :
MVVRTQNSESKIKEFFEFCKENEVEFVDFRFSDIKGTWNHIAYSFGALTHGMFKEGIPFDASSFKGWQGIEHSDMILTPD
LVRYFIDPFSADVSVVVFCDVYDVYKNQPYEKCPRSIAKKALQHLKDSGLGDVAYFGAENEFFIFDSIKIKDASNSQYYE
VDSEEGEWNRDRSFENGVNFGHRPGKQGGYMPVPPTDTMMDIRTEIVKVLNQVGLETFVVHHEVAQAQGEVGVKFGDLVE
AADNVQKLKYVVKMVAHLNGKTATFMPKPLYGDNGSGMHTHVSVWKNNENLFSGETYKGLSELALHFLGGVLRHARGLAA
FTNASTNSYKRLIPGYEAPSILTYSANNRSASVRIPYGISKNSARFEFRFPDSSSNPYLAFAAILMAGMDGVKNKIDPGE
AMDINLFKLTLDEIREKGIKQMPHTLRRSLEEMLADKQYLKEGQVFSEEFIQAYQSLKFNAEVFPWESKPHPFEFITTYS
C

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
glnA YP_003728749.1 glutamine synthetase Not tested cag PAI Protein 0.0 99

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
glnA YP_007983616.1 glutamine synthetase VFG1399 Protein 1e-89 45