Gene Information

Name : K751_07100 (K751_07100)
Accession : YP_007984371.1
Strain : Helicobacter pylori UM066
Genome accession: NC_021218
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase
Function : -
COG functional category : -
COG ID : -
EC number : 2.5.1.48
Position : 103046 - 104188 bp
Length : 1143 bp
Strand : +
Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology.

DNA sequence :
ATGCACATGCAAACAAAACTAATCCATGGGGGCATTAGTGAGGACGCGACAACGGGGGCGGTGAGCGTGCCTATTTATCA
AACTTCCACCTACCGCCAAGACGCCATAGGCCACCATAAGGGCTATGAATACTCCCGCTCAGGCAACCCCACGCGCTTTG
CTTTAGAAGAACTCATCGCCGATTTAGAAGGAGGGGTTAAGGGGTTTGCTTTTGCCTCTGGTTTAGCTGGAATCCACGCC
GTTTTTTCCCTCTTGCAATCAGGCGATCATGTGCTATTAGGCGATGATATTTATGGGGGGACTTTTCGCTTGTTCAATAA
AGTGCTTGTCAAAAACGACCTTTCTTGCACCATTATAGACACTAGCGATATATCCCAAATTAAAAAGGCTATCAAGCCCA
ACACCAAAGCCCTTTATTTAGAAACCCCTAGTAACCCCTTGCTTAAAATCACGGATTTAGCGCAATGCACTAGTGTCGCT
AAAGATCATGGTTTGCTCACTATCGTGGATAACACCTTTGCCACCCCCTATTGCCAAAACCCGCTTCTTTTGGGGGCGGA
TATTGTGGCGCATAGCGGCACCAAATACTTAGGCGGGCATAGCGATGTGGTCGCTGGGCTTGTAACCACTAATAATGAAG
CGCTAGCCCAAGAGATCGCTTTTTTCCAAAACGCTATCGGTGGGGTTTTAGGCCCTCAAGACAGCTGGCTGTTGCAAAGA
GGGATTAAAACGCTAGGATTGCGCATGGAGGCCCATCAAAAAAATGCCCTTTGCGTGGCTGAGTTTTTAGAAAAACACCC
TAAAGTGGAAAGGGTTTATTACCCGGGCTTGAGCACTCACCCTAACCACGAACTGGCCAAAAAACAGATGCGTGGCTTTA
GCGGGATGCTCTCTTTCACTCTCAAAAATGACAGCGAAGCGGTTGCTTTTGTGGAAAGCCTTAAACTATTCATTTTAGGC
GAGAGTTTGGGCGGAGTGGAAAGCTTGGTGGGAATTCCTGCACTTATGACCCATGCGTGTATCCCCAAAGCGCAACGAGA
AGCTGCCGGGATTAGAGATGGCCTGGTGCGCTTGTCTGTAGGGATTGAGCATGAACAGGATTTGTTAGAAGATTTAGAGC
AAGCGTTCACTAAAATAGGCTAA

Protein sequence :
MHMQTKLIHGGISEDATTGAVSVPIYQTSTYRQDAIGHHKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIHA
VFSLLQSGDHVLLGDDIYGGTFRLFNKVLVKNDLSCTIIDTSDISQIKKAIKPNTKALYLETPSNPLLKITDLAQCTSVA
KDHGLLTIVDNTFATPYCQNPLLLGADIVAHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQR
GIKTLGLRMEAHQKNALCVAEFLEKHPKVERVYYPGLSTHPNHELAKKQMRGFSGMLSFTLKNDSEAVAFVESLKLFILG
ESLGGVESLVGIPALMTHACIPKAQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFTKIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-98 54
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-97 54
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 1e-72 47

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
K751_07100 YP_007984371.1 cystathionine beta-lyase BAC0207 Protein 2e-61 42