Gene Information

Name : K751_03370 (K751_03370)
Accession : YP_007983654.1
Strain : Helicobacter pylori UM066
Genome accession: NC_021218
Putative virulence/resistance : Virulence
Product : cytochrome C oxidase subunit II
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 960385 - 963912 bp
Length : 3528 bp
Strand : -
Note : Derived by automated computational analysis using gene prediction method: Protein Homology.

DNA sequence :
ATGACTAACGAAACCATTGATCAAACACCAACACCAGATCAAACACCAAACCAAACGGATTTTGTTCCGCAACGATTTAT
CAATAATCTTCAAGTAGCTTTTATTAAAGTTGATAACGCTGTCGCTTCATTTGATCCTGATCAAAAACCAATCGTTGATA
AGAATGATAGGGATAACAGGCAAGCTTTTGAGAAAATCTCGCAACTAAGGGAAGAATACGCCAATAAAGCGATCAAAAAT
CCTGCCAAAAAGAATCAGTATTTTTCAGACTTTATCAATAAGAGCAATGATTTGATCAACAAAGACAATCTCATTGCTGT
AGATTCTTCCGTAGAGAGCTTTAAGAAATTTGGGGATCAGCGTTACCAAATTTTTACGAGTTGGGTGTCCCTTCAAAAAG
ATCCGTCTAAAATCAACACCCAACAAATCCAAAATTTTATGGAAAATATCATACAACCCCCTATCTCTGATGATAAGGAA
AAAGCGGAGTTTTTGAGGTCTGCCAAACAATCTTTTGCAGGAATTATCATAGGGAATCAAATCCGATCGGATCAAAAATT
CATGGGCGTGTTTGATGAATCTTTGAAAGAAAGGCAAGAAGCAGAAAAAAATGCAGAGCCTGCTGGTGGGGATTGGCTTG
ATATTTTTTTATCATTTGTGTTTAACAAAAAACAATCTTCCGATCTCAAAGAAACGCTCCATCAAGAGCCAAGGCCTGAT
TTTGAACAAAATTTAGCCACTACCACCACCAACATACAAGGTTTACCGCCTGAAGCTAGAGATTTGCTTGATGAAAGGGG
TAATTTTTTTAAATTCACTCTTGGTGATGTGGAGATGTTGGATGTTGAGGGAGTCGCTGACAAGGATCCTAATTACAAGT
TCAATCAGTTATTGATCCACAATAACGCTTTATCTTCTGTGCTAATGGGGAGTCATAGCAACATAGAACCTGAAAAAGTT
TCATTATTGTATGGGGATAATGGTGGTCCTGAAGCTAGGCATGACTGGAACGCTACCGTTGGTTATAAAGACCAACAAGG
CAACAATGTGGCCACACTCATTAATGCGCATCTTAATAACGGCAGTGGGTTAATCATAGCGGGTAATGAAAATGGGATTA
AAAATCCTAGCTTCTATCTCTACAAAGAAGACCAACTCACAGGCTTGAAACAAGCAATGAGTCAAGAAGAGATCCAAAAC
AAAGTGGATTTCATGGAATTTCTTGCAAAAAACAACGCTAAATTAGACAACTTGAGCAAGGAAGAGAAAGAAAAATTCCA
AACTGAGATTGGAAATTTCCAAAAAGACCGTAAGGCTTATTTGGACGCTCTAGGGAATGATCACATTGCTTTTGTTTCTA
AAAAAGACTCAAAACATTTAGCTTTGGTTACTGAGTTTGGTAATGGGGAAGTGAGCTATACTCTCAAAGATTATGGGAAA
AAACAAGACAAAGCTTTAGATGGGGAGACAAAAACCACTCTTCAAGGTAGCCTAAAATATGATGGCGTGATGTTTGTCAA
TTATTCTAATTTCAAATACACCAACGCCTCCAAGAGTCCTGATAAGGGTGTGGGCACTACGAATGGCGTTTCTCATTTGG
AAGCGAATTTTAGCAAGGTAGCTGTCTTTAATTTGCCTAATTTAAATAATCTCGCTATCACTAATTATATAAGGCGAGAT
TTAGAAGATAAATTGTTGGCTAAAGGATTGTCCCCACAAGAAGCTAATAAGCTCATCAAAGACTTTTTGAACAGCAACAA
AGAATTGGTTGGAAAAGTTTCAAACTTCAATAAAGCTGTAGCTGAAGCTAAAAACACAGGCAATTATGATGAAGTGAAAA
AAGCTCAGAAAGATCTTGAAAAATCTCTAAGGAAACGAGAGCATTTAGAGAAAGAAGTAGCGAAAAAATTGGAGAGCAGA
AACGACAACAAAAATAGAATGGAAGCAAAAGCTCAAGCTAACAGCCAAAAAGATAAGATTTTTGCACTTATCAATAAAGA
GGCTAGTAAGGAAGCAAGAGCGGCCGCTTTCGATCCGAATCTTAAAGGCGTCAGGAGCGAATTGTCTGATAAACTTGAAA
ATATCAACAAGAATTTGAAAGACTTTGGCAAATCTTTTGATGAACTCAAAAATGGCAAAAATAATGATTTCAGCAAGGCA
GAAGAAACGCTAAAAGCCCTTAAAGACTCGGTGAAAGATTTAGGCATCAATCCGGAATGGATTTCAAAAATTGAAAACCT
TAATGCAGCTTTGAATGATTTCAAAAATGGCAAAAATAAGGATTTCAGCAAGGTAACACAAGCAAAAAGCGACCTTGAAA
ATTCCATTAAGGATGTGATCATTAATCAAAAGATAACGGATAAAGTTGACAATCTCAATCAGGCTGTATCAGAGACTAAA
TTAACAGGCGATTTCAGTAAGGTAGAGCAAGCCCTAGCCGAACTCAAAAGCTTGTCATTGGATCTTGGAAAAAATTCTGA
TCTACAATCCGTTAAAAATAGTGTGAATGGAACCCTAGTCGGTAATGGGTTGTCTAAAACAGAAGCCACAACGCTCACCA
AAAATTTTTCGGATATCAGGAAAGAATTGAACGAGAAATTATTTGGAAATTCCAATAACAATAATAATGGACTCAAAAAC
AACACAGAGCCTATTTACGCTCAAGTTAATAAAAAGAAAGCAGGACAAGCAACTAGCCCTGAAGAGCCCATTTACGCTCA
AGTTGCCAAAAAGGTGAGTGCAAAAATTGACCAACTCAACGAAGCTACATCAGCAATAAATAGAAAAATTGACCGGATTA
ACAAAATTGCATCAGCAGGTAAAGGAGTGGGCGGTTTCAGTGGAGCAGGGCGATCAGCTAGCCCTGAACCCATTTACGCT
ACAATTGATTTTGATGAGGCAAATCAAGCAGGCTTCCCTTTGAGAAGAAGTGCTGCAGTTAATGATCTCAGTAAAGTAGG
GCTTTCAAGGGAACAAGAATTGACTCGTAGAATTGGCGATCTCAATCAGGCAGTGTCAGAAGCTAAAACAGGTCATTTTG
GCAACCTAGAACAAAAGATAGATGAACTCAAAGATTCTACAAAAAAGAATGCTTTGAAGCTATGGGTTGAAAGCGCGAAA
CAAGTGCCTACTGGTTTGCAAGCGAAATTGGACAATTACGCTACTAATAGCCACACACGCATTAATAGCAATGTCCAAAG
TGGAACAATCAATGAAAAAGCGACCGGCATGCTAACGCAAAAAAACCCTGAGTGGCTCAAGCTCGTGAATGATAAGATAG
TTGCACATAATGTGGGAAGTGCTCATTTGTCAGAGTATGATAAAATTGGATTCAACCAAAAGAATATGAAAGATTATTCT
GATTCGTTCAAGTTTTCCACCAAGTTGAACAATGCCGTAAAAGACATTAAGTCTAGCTTTGTGCAATTTTTAACCAATAC
ATTTTCTACAGGATCTTACAGCTTGATGAAAGCAAATGTGGAGCATGGAGTCAAAAATACTACAAAAAGTGGTTTCCAGA
AATCTTAA

Protein sequence :
MTNETIDQTPTPDQTPNQTDFVPQRFINNLQVAFIKVDNAVASFDPDQKPIVDKNDRDNRQAFEKISQLREEYANKAIKN
PAKKNQYFSDFINKSNDLINKDNLIAVDSSVESFKKFGDQRYQIFTSWVSLQKDPSKINTQQIQNFMENIIQPPISDDKE
KAEFLRSAKQSFAGIIIGNQIRSDQKFMGVFDESLKERQEAEKNAEPAGGDWLDIFLSFVFNKKQSSDLKETLHQEPRPD
FEQNLATTTTNIQGLPPEARDLLDERGNFFKFTLGDVEMLDVEGVADKDPNYKFNQLLIHNNALSSVLMGSHSNIEPEKV
SLLYGDNGGPEARHDWNATVGYKDQQGNNVATLINAHLNNGSGLIIAGNENGIKNPSFYLYKEDQLTGLKQAMSQEEIQN
KVDFMEFLAKNNAKLDNLSKEEKEKFQTEIGNFQKDRKAYLDALGNDHIAFVSKKDSKHLALVTEFGNGEVSYTLKDYGK
KQDKALDGETKTTLQGSLKYDGVMFVNYSNFKYTNASKSPDKGVGTTNGVSHLEANFSKVAVFNLPNLNNLAITNYIRRD
LEDKLLAKGLSPQEANKLIKDFLNSNKELVGKVSNFNKAVAEAKNTGNYDEVKKAQKDLEKSLRKREHLEKEVAKKLESR
NDNKNRMEAKAQANSQKDKIFALINKEASKEARAAAFDPNLKGVRSELSDKLENINKNLKDFGKSFDELKNGKNNDFSKA
EETLKALKDSVKDLGINPEWISKIENLNAALNDFKNGKNKDFSKVTQAKSDLENSIKDVIINQKITDKVDNLNQAVSETK
LTGDFSKVEQALAELKSLSLDLGKNSDLQSVKNSVNGTLVGNGLSKTEATTLTKNFSDIRKELNEKLFGNSNNNNNGLKN
NTEPIYAQVNKKKAGQATSPEEPIYAQVAKKVSAKIDQLNEATSAINRKIDRINKIASAGKGVGGFSGAGRSASPEPIYA
TIDFDEANQAGFPLRRSAAVNDLSKVGLSREQELTRRIGDLNQAVSEAKTGHFGNLEQKIDELKDSTKKNALKLWVESAK
QVPTGLQAKLDNYATNSHTRINSNVQSGTINEKATGMLTQKNPEWLKLVNDKIVAHNVGSAHLSEYDKIGFNQKNMKDYS
DSFKFSTKLNNAVKDIKSSFVQFLTNTFSTGSYSLMKANVEHGVKNTTKSGFQKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cagA BAC10430.1 CagA Virulence cag PAI Protein 0.0 98
cagA BAD51749.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 97
cagA BAD51762.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 97
cagA YP_005777288.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 97
HP0547 BAD13963.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 97
HP0547 BAD13880.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 97
cagA BAC10435.1 CagA Virulence cag PAI Protein 0.0 97
cagA AAF17597.1 CagA Virulence cag PAI Protein 0.0 97
HP0547 BAD14072.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 97
cagA BAC10421.1 CagA Virulence cag PAI Protein 0.0 97
cagA BAD51755.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 97
HP0547 BAD13799.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 97
cagA BAD51754.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 97
cagA YP_005779046.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 97
cagA YP_005775747.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 97
cagA BAC10431.1 CagA Virulence cag PAI Protein 0.0 97
cagA BAC10424.1 CagA Virulence cag PAI Protein 0.0 97
cagA YP_005774524.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 96
cagA BAC10419.1 CagA Virulence cag PAI Protein 0.0 96
cagA BAC10433.1 CagA Virulence cag PAI Protein 0.0 96
HP0547 BAD14018.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 96
cagA BAC10426.1 CagA Virulence cag PAI Protein 0.0 96
cagA BAD51744.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 96
cagA BAC10420.1 CagA Virulence cag PAI Protein 0.0 96
HP0547 BAD13853.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 95
cagA BAC10422.1 CagA Virulence cag PAI Protein 0.0 93
HP0547 BAD13826.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 93
cagA BAC10427.1 CagA Virulence cag PAI Protein 0.0 88
cagA BAD51764.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 87
cagA BAC10423.1 CagA Virulence cag PAI Protein 0.0 84
cagA BAD51752.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 83
cagA BAD51756.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 82
cagA AGC69806.1 cag pathogenicity island protein A Virulence cag PAI Protein 0.0 82
cagA BAD51759.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 81
cagA BAD51766.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 81
cagA BAC10429.1 CagA Virulence cag PAI Protein 0.0 81
HP0547 BAD13935.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 81
cagA BAD51758.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 81
cagA BAD51753.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 81
cagA YP_003728762.1 cytotoxin-associated protein A Virulence cag PAI Protein 0.0 81
cagA BAD51751.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 80
cagA BAD51750.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 80
cagA BAD51760.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 80
cagA BAD51761.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 79
cagA NP_223213.1 cag island protein, cytotoxicity associated immunodominant antigen Virulence cag PAI Protein 0.0 79
cagA AAR03970.1 CagA Virulence cag PAI Protein 0.0 79
cagA AAR03939.1 CagA Virulence cag PAI Protein 0.0 79
cagA AAC44706.1 CagA Virulence cag PAI Protein 0.0 78
HP0547 NP_207343.1 cag pathogenicity island protein (cag26) Virulence cag PAI Protein 0.0 78
cagA AAR03909.1 CagA Virulence cag PAI Protein 0.0 78
cagA AAR03881.1 CagA Virulence cag PAI Protein 0.0 78
HP0547 BAD14045.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 77
cagA BAD51747.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 77
cagA BAC10428.1 CagA Virulence cag PAI Protein 0.0 77
HP0547 BAD13908.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 77
HP0547 BAD13990.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 75
cagA BAC10432.1 CagA Virulence cag PAI Protein 0.0 75
cagA AAF17598.1 CagA Virulence cag PAI Protein 0.0 75

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
K751_03370 YP_007983654.1 cytochrome C oxidase subunit II VFG0306 Protein 0.0 78