Gene Information

Name : glnA (K750_04225)
Accession : YP_007982201.1
Strain : Helicobacter pylori UM037
Genome accession: NC_021217
Putative virulence/resistance : Virulence
Product : glutamine synthetase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.1.2
Position : 761122 - 762567 bp
Length : 1446 bp
Strand : -
Note : forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltra

DNA sequence :
ATGATAGTAAGAACTCAAAATAGTGAAAGCAAGATCAAAGAATTTTTTGAATTTTGCAAAGAAAATGAAGTGGAATTTGT
GGATTTTAGATTCAGCGATATTAAAGGCACTTGGAATCACATCGCTTATTCTTTTGGGGCTTTAACGCATGGCATGTTTA
AAGAGGGGATTCCTTTTGATGCGAGTTGTTTTAAAGGCTGGCAAGGCATTGAACACTCCGATATGATTTTAACCCCCGAT
TTGGTGCGTTATTTCATTGACCCTTTTAGCGCGGATGTGAGCGTGGTCGTGTTTTGCGATGTGTATGATGTGTATAAAAA
CCAGCCTTATGAAAAATGCCCTAGAAGTATCGCTAAAAAAGCCTTACAGCATTTAAAAGATTCAGGTTTGGGCGATGTGG
CTTATTTTGGCGCGGAGAATGAATTTTTTATCTTTGATTCCATTAAGATTAAAGACGCTTCCAATTCCCAATACTACGAA
GTGGATAGTGAAGAGGGCGAATGGAATAGGGATAGAAGTTTTGAAAATGGCGTCAATTTTGGGCATAGACCGGGCAAACA
AGGGGGCTATTTGCCTGTACCGCCAACGGATACGATGATGGATATTCGCACAGAAATTGTGAAAGTCTTAAACCAAGTGG
GGCTAGAAACTTTTGTCGTCCATCATGAAGTCGCGCAAGCGCAAGGCGAAGTGGGCGTGAAATTTGGGGATTTAGTGGAA
GCGGCTGATAATGTCCAAAAACTCAAGTATGTGGTTAAAATGGTCGCTCATTTAAACGGGAAAACCGCCACTTTCATGCC
AAAACCTTTATATGGGGATAACGGGAGCGGGATGCACACCCATGTGAGCGTTTGGAAAAACAACGAAAACCTTTTTAGTG
GCGAAACTTACAAGGGCTTGAGTGAGTTAGCGTTGCATTTTTTAGGGGGCGTGTTGCGCCACGCTAGAGGGTTGGCCGCT
TTCACTAACGCTTCCACTAATTCTTACAAACGCCTGATTCCGGGATATGAAGCCCCATCTATTTTAACTTATTCGGCTAA
TAATAGGAGTGCGAGCGTGCGTATCCCTTATGGGATTTCTAAAAACAGCGCGAGGTTTGAATTCAGGTTTCCTGACAGCT
CATCAAACCCCTACTTGGCTTTTGCAGCGATTTTAATGGCGGGTATTGATGGCGTTAAAAACAAGATCGATCCCGGCGAA
GCGATGGATATTAACCTTTTCAAATTGACTTTAGATGAAATTAGGGAAAAAGGTATCAAACAAATGCCCCACACTTTAAG
GCGATCGTTAGAAGAAATGCTAGCCGATAAGCAGTATTTAAAAGAAGGTCAGGTCTTTAGCGAAGAATTTATTCAAGCTT
ATCAGTCTCTTAAATTCAACGCTGAAGTGTTCCCATGGGAGAGCAAGCCCCATCCCTTTGAATTTATCACCACTTATTCA
TGCTAA

Protein sequence :
MIVRTQNSESKIKEFFEFCKENEVEFVDFRFSDIKGTWNHIAYSFGALTHGMFKEGIPFDASCFKGWQGIEHSDMILTPD
LVRYFIDPFSADVSVVVFCDVYDVYKNQPYEKCPRSIAKKALQHLKDSGLGDVAYFGAENEFFIFDSIKIKDASNSQYYE
VDSEEGEWNRDRSFENGVNFGHRPGKQGGYLPVPPTDTMMDIRTEIVKVLNQVGLETFVVHHEVAQAQGEVGVKFGDLVE
AADNVQKLKYVVKMVAHLNGKTATFMPKPLYGDNGSGMHTHVSVWKNNENLFSGETYKGLSELALHFLGGVLRHARGLAA
FTNASTNSYKRLIPGYEAPSILTYSANNRSASVRIPYGISKNSARFEFRFPDSSSNPYLAFAAILMAGIDGVKNKIDPGE
AMDINLFKLTLDEIREKGIKQMPHTLRRSLEEMLADKQYLKEGQVFSEEFIQAYQSLKFNAEVFPWESKPHPFEFITTYS
C

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
glnA YP_003728749.1 glutamine synthetase Not tested cag PAI Protein 0.0 99

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
glnA YP_007982201.1 glutamine synthetase VFG1399 Protein 2e-89 45