Gene Information

Name : K750_05020 (K750_05020)
Accession : YP_007982353.1
Strain : Helicobacter pylori UM037
Genome accession: NC_021217
Putative virulence/resistance : Virulence
Product : cytochrome C oxidase subunit II
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 597062 - 600604 bp
Length : 3543 bp
Strand : -
Note : Derived by automated computational analysis using gene prediction method: Protein Homology.

DNA sequence :
ATGACTAACGAAACCATTAACCAACAACCACAAACCGAAGCGGCTTTTAACCCGCAGCAATTTATCAATAATCTTCAAGT
CGCTTTTCTTAAAGTTGATAACGCTGTCGCTTCATACGATCCTGATCAAAAACCAATCGTTGATAAGAACGATAGGGATA
ATAGGCAAGCTTTTGATGGAATCTCGCAATTAAGGGAAGAATACTCCAATAAAGCGATCAAAAATCCTACCAAAAAGAAT
CAGTATTTTTCAGACTTTATCAATAAGAGCAATGATTTAATCAACAAAGACGCTCTCATTGATGTAGAATCTTCCACAAA
GAGCTTTCAGAAATTTGGGGATCAGCGTTACCGAATTTTCACAAGTTGGGTGTCCCATCAAAACGATCCGTCTAAAATCA
ACACCCGATCGATCCGAAATTTTATGGAAAATATCATACAACCCCCTATCCCTGATGACAAAGAAAAAGCAGAGTTTTTG
AAATCTGCCAAACAATCTTTTGCAGGAATCATCATAGGGAATCAAATCCGAACGGATCAAAAGTTCATGGGCGTATTTGA
TGAATCCTTGAAAGAAAGGCAAGAAGCAGAAAAAAATGGAGGGCCTACTGGTGGGGATTGGTTGGATATTTTTTTATCAT
TTATATTTGACAAAAAACAATCTTCTGATGTCAAAGAAGCAATCAATCAAGAACCAGTTCCCCATGTCCAACCAGATATA
GCCACTACCACCACCCACATACAAGGCTTACCGCCTGAATCTAGGGATTTGCTTGATGAAAGGGGTAATTTTTCTAAATT
CACTCTTGGCGATATGGAAATGTTAGATGTTGAGGGAGTCGCTGACATTGATCCCAATTACAAGTTCAATCAATTATTGA
TTCACAATAACGCTCTGTCTTCTGTGTTAATGGGGAGTCATAATGGCATAGAACCTGAAAAAGTTTCATTATTGTATGCG
GGCAATGGTGGTTTTGGAGCCAAGCACGATTGGAACGCCACCGTTGGTTATAAAGACCAACAAGGTAACAATGTGGCTAC
AATAATTAATGTGCATATGAAAAACGGCAGTGGCTTAGTCATAGCAGGTGGTGAGAAAGGGATTAACAACCCTAGTTTTT
ATCTCTACAAAGAAGACCAACTCACAGGCTCACAACGAGCATTGAGTCAAGAAGAGATCCGAAACAAAATAGATTTCATG
GAATTTCTTGCACAAAACAATGCTAAATTAGACAACTTGAGCGTGAAAGAGAAAGAAAAATTCCAAAATGAGATTGAAGA
TTTTCAAAAAGACTCTAAGGCTTATTTAGACGCCCTAGGGAATGATCGTATTGCTTTTGTTTCTAAAAAAGACCCAAAAC
ATTCAGCTTTAATTACTGAGTTTGGTAATGGGGATTTGAGCTACACTCTCAAAGATTATGGGAAAAAAGCAGATAAAGCT
TTGGATAGGGAGAAAAATGTCACTCTTCAAGGTAGCCTAAAACATGATGGCGTGATGTTTGTTGATTATTCTAATTTCAA
ATATACCAACGCCTCCAAGAATCCCAATAAGGGTGTAGGTGCTACGAATGGCGTTTCCCATTTAGAAGCAGGCTTTGACA
AGGTAGCTATCTTTAATTTGCCTGATTTAAATAATCTCGCTATCACTAGTTTCGTAAGGCGGAATTTAGAGGATAAACTA
GCCACTAAAGGATTGTCCCTACAAGAAGCTAATAAGCTTATCAAAGATTTTTTGAGCAGCAACAAAGAATTGGTTGGAAA
AGCTTTAAACTTCAATAAAGCTGTGGCTGAAGCTAAAAACACAGGCAACTATGATGAAGTGAAACGAGCTCAGAAAGATC
TTGAAAAATCTCTAAGGAGACGAGAGCATTTAGAGAAAAATGTAGCGAAAAATTTGGAGAGCAAAAGCGGCAACAAAAAT
AAAATGGAAGCAAAAGCTCAAGCTAACAGCCAAAAAGATGAGATTTTTGCGTTGATCAATAAAGAGGCTAATAGAGACGC
AAGAGCAATCGCTTACGCTCAGAATCTTAAAGGCATCAAAAGGGAATTGTCTGATAAACTTGAAAATGTCAACAAGAATT
TGAAAGACTTTAGTGAGTCTTTTGATGAATTCAAAAATGGCAAAAATAAGGATTTCAGCAAGGCAGAAGAAACGCTAAAA
GCCCTTAAAGGCTCGGTGAAAGATTTAGGTATCAATCCAGAATGGATTTCAAAAGTTGAAAACCTTAATGCAGCTTTGAA
TGAATTCAAAAATGGCAAAAATAAGGATTTCAGCAAGGTAACGCAAGCCAAAAGCGACCTTGAAAATTCCGTTAAAGATG
TGATCATCAATCAAAAGGTAACGGATAAAGTTGACAATCTCAGTTCGGCGGTATCAGTGGCTAAAGCAACGGGTGATTTC
AGTAGAGTAAATCAAGCGTTAGCCGATCTCAAAAACTTCTCAAAGGAGCAATTGGCTCAACAAGCTCAAAAAAATGAAGA
TTTCAATACTGGAAAAAATTCTGCACTATACCAATCCGTTAAGAATGGTGTGAATGGAACCCTAGTCGGTAATGGGTTAT
CTAAAGCAGAAGCCACAACTCTTTCTAAAAACTTTTCGGACATCAAGAAAGAGTTGAATGCAAAATTGGGGAATTTCAAT
AACAATAACAATAATGGACTCAAAAACGAACCCATTTACGCTAAAGTTAATAAAAAGAAAACAGAGCAAGCAGCTAGCCC
TGAAGAACCCATTTACGCTCAAGTTGCTAAAAAGGTAAATGCAAAAATTGACCGACTCAATCAAATAGCAAGTGGTTTGG
GTGGTGTAGGGCAAGCAGTGGGCTTCCCTTTGAAAAGGCATGATAAAGTTGATGATCTCAGTAAGGTAGGGCTTTCAGCT
AGCCCTGAACCCATTTATGCTACGATTGATGATCTCGGCGGACCTTTCCCTTTGAAAAGGCATTCTAAAGTTGATGATCT
CGGTAAGGTAGGGCTTTCAAGGAATCAAGAATTGGCTCAGAAAATTGACAATCTCAATCAAGCGGTATCAGAAGCTAAAG
CAGGTTTTTTTGGCAATCTAGAGCAAACGATAGACAATCTCAAAGATTCTGCAAAAAACAATCCTGTGAATCTATGGGCT
GAAAGTGCAAAAAAAGTGCCTGCTAGTTTGTCAGCGAAATTGGACAATTACGCTACTAACAGCCACACACGCATTAATAG
CAATATCAAAAATGGAGCAATCAATGAAAAAGCGACCGGCATGCTAACGCAAAAAAACCCTGAGTGGCTCAAGCTCGTGA
ATGATAAGATAGTTGCGCATAATGTGGGAAGCGTTCCTTTGTCAGAGTATGATAAAATTGGCTTCAACCAGAAAAATATG
AAAGATTATTCTGATTCGTTCAAGTTTTCCACCAAGTTGAACAATGCCGCAAAAGACATTAAGTCTGGCTTTACGCAATT
TTTAACCAATGCATTTTCTACAGGATATTACTGCTTGGCAGGAGAAAATGCAGAGCATGGAATCAAAAATGTTAATACAA
AAGGTGGTTTCCAAAAATCTTAA

Protein sequence :
MTNETINQQPQTEAAFNPQQFINNLQVAFLKVDNAVASYDPDQKPIVDKNDRDNRQAFDGISQLREEYSNKAIKNPTKKN
QYFSDFINKSNDLINKDALIDVESSTKSFQKFGDQRYRIFTSWVSHQNDPSKINTRSIRNFMENIIQPPIPDDKEKAEFL
KSAKQSFAGIIIGNQIRTDQKFMGVFDESLKERQEAEKNGGPTGGDWLDIFLSFIFDKKQSSDVKEAINQEPVPHVQPDI
ATTTTHIQGLPPESRDLLDERGNFSKFTLGDMEMLDVEGVADIDPNYKFNQLLIHNNALSSVLMGSHNGIEPEKVSLLYA
GNGGFGAKHDWNATVGYKDQQGNNVATIINVHMKNGSGLVIAGGEKGINNPSFYLYKEDQLTGSQRALSQEEIRNKIDFM
EFLAQNNAKLDNLSVKEKEKFQNEIEDFQKDSKAYLDALGNDRIAFVSKKDPKHSALITEFGNGDLSYTLKDYGKKADKA
LDREKNVTLQGSLKHDGVMFVDYSNFKYTNASKNPNKGVGATNGVSHLEAGFDKVAIFNLPDLNNLAITSFVRRNLEDKL
ATKGLSLQEANKLIKDFLSSNKELVGKALNFNKAVAEAKNTGNYDEVKRAQKDLEKSLRRREHLEKNVAKNLESKSGNKN
KMEAKAQANSQKDEIFALINKEANRDARAIAYAQNLKGIKRELSDKLENVNKNLKDFSESFDEFKNGKNKDFSKAEETLK
ALKGSVKDLGINPEWISKVENLNAALNEFKNGKNKDFSKVTQAKSDLENSVKDVIINQKVTDKVDNLSSAVSVAKATGDF
SRVNQALADLKNFSKEQLAQQAQKNEDFNTGKNSALYQSVKNGVNGTLVGNGLSKAEATTLSKNFSDIKKELNAKLGNFN
NNNNNGLKNEPIYAKVNKKKTEQAASPEEPIYAQVAKKVNAKIDRLNQIASGLGGVGQAVGFPLKRHDKVDDLSKVGLSA
SPEPIYATIDDLGGPFPLKRHSKVDDLGKVGLSRNQELAQKIDNLNQAVSEAKAGFFGNLEQTIDNLKDSAKNNPVNLWA
ESAKKVPASLSAKLDNYATNSHTRINSNIKNGAINEKATGMLTQKNPEWLKLVNDKIVAHNVGSVPLSEYDKIGFNQKNM
KDYSDSFKFSTKLNNAAKDIKSGFTQFLTNAFSTGYYCLAGENAEHGIKNVNTKGGFQKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cagA AAR03881.1 CagA Virulence cag PAI Protein 0.0 95
HP0547 BAD14045.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 94
cagA AAR03970.1 CagA Virulence cag PAI Protein 0.0 94
cagA AAF17598.1 CagA Virulence cag PAI Protein 0.0 94
cagA AAC44706.1 CagA Virulence cag PAI Protein 0.0 93
HP0547 NP_207343.1 cag pathogenicity island protein (cag26) Virulence cag PAI Protein 0.0 93
cagA AAR03909.1 CagA Virulence cag PAI Protein 0.0 93
cagA BAD51747.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 91
cagA BAC10428.1 CagA Virulence cag PAI Protein 0.0 90
HP0547 BAD13908.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 90
cagA AAR03939.1 CagA Virulence cag PAI Protein 0.0 87
cagA NP_223213.1 cag island protein, cytotoxicity associated immunodominant antigen Virulence cag PAI Protein 0.0 86
cagA BAD51760.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 86
cagA BAD51750.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 86
cagA BAD51758.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 86
cagA BAD51751.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 85
cagA BAD51761.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 85
cagA BAC10432.1 CagA Virulence cag PAI Protein 0.0 85
HP0547 BAD13990.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 85
cagA BAD51756.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 84
cagA BAD51753.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 84
cagA BAD51752.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 84
cagA YP_003728762.1 cytotoxin-associated protein A Virulence cag PAI Protein 0.0 84
cagA BAD51766.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 84
cagA BAC10429.1 CagA Virulence cag PAI Protein 0.0 84
HP0547 BAD13935.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 84
cagA AGC69806.1 cag pathogenicity island protein A Virulence cag PAI Protein 0.0 84
cagA BAD51759.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 83
cagA BAD51764.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 81
cagA BAC10419.1 CagA Virulence cag PAI Protein 0.0 79
cagA BAD51754.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 78
cagA BAC10426.1 CagA Virulence cag PAI Protein 0.0 78
cagA YP_005777288.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 78
cagA BAD51749.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 78
cagA YP_005774524.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 78
HP0547 BAD14072.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 78
cagA BAC10421.1 CagA Virulence cag PAI Protein 0.0 78
HP0547 BAD13799.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 78
cagA BAC10431.1 CagA Virulence cag PAI Protein 0.0 78
cagA BAD51755.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 78
HP0547 BAD13963.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 78
cagA YP_005779046.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 78
cagA BAC10435.1 CagA Virulence cag PAI Protein 0.0 78
cagA BAD51762.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 78
cagA BAC10420.1 CagA Virulence cag PAI Protein 0.0 77
cagA BAC10433.1 CagA Virulence cag PAI Protein 0.0 77
HP0547 BAD14018.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 77
cagA BAD51744.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 77
cagA YP_005775747.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 77
HP0547 BAD13880.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 77
cagA AAF17597.1 CagA Virulence cag PAI Protein 0.0 77
HP0547 BAD13853.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 74
cagA BAC10427.1 CagA Virulence cag PAI Protein 0.0 73
cagA BAC10430.1 CagA Virulence cag PAI Protein 0.0 68
cagA BAC10422.1 CagA Virulence cag PAI Protein 0.0 68
HP0547 BAD13826.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 68
cagA BAC10423.1 CagA Virulence cag PAI Protein 0.0 68
cagA BAC10424.1 CagA Virulence cag PAI Protein 0.0 67

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
K750_05020 YP_007982353.1 cytochrome C oxidase subunit II VFG0306 Protein 0.0 93