Gene Information

Name : K750_09475 (K750_09475)
Accession : YP_007982929.1
Strain : Helicobacter pylori UM037
Genome accession: NC_021217
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase
Function : -
COG functional category : -
COG ID : -
EC number : 2.5.1.48
Position : 1673393 - 1674535 bp
Length : 1143 bp
Strand : -
Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology.

DNA sequence :
ATGCGCATGCAAACCAAATTAATCCATGGGGGCATTAGCGAGGACGCGACAACGGGGGCGGTGAGCGTGCCTATTTATCA
AACTTCCACCTACCGCCAAGACGCCATAGGCCGCCACAAGGGCTATGAATACTCTCGCTCAGGCAACCCCACGCGCTTTG
CTTTAGAAGAACTCATCGCTGATTTAGAAGGGGGGGTTAAGGGGTTTGCTTTTGCTTCTGGACTAGCCGGGATCCACGCC
GTTTTTTCCCTCTTGCAATCAGGCGATCATGTGTTATTAGGCGATGATGTTTATGGGGGGACTTTCCGCTTGTTTAATAA
AGTGCTTGTCAAAAACGGGCTTTCTTGCACCATTATAGACACTAGCGATCTATCCCAAATCAAAAAGGCTATCAAACCCA
ACACCAAAGCTCTTTATTTAGAAACCCCTAGTAACCCCTTGCTTAAAATCACGGATTTAGCGCAATGCGCTAGTGTCGCT
AAGGATCATGGGTTGCTCACTATCGTGGATAACACCTTTGCCACCCCCTATTATCAAAACCCGCTTCTTTTAGGAGCGGA
CATTGTGGTGCATAGTGGCACCAAATACTTAGGCGGTCATAGCGATGTAGTCGCCGGGCTTGTAACCACCAATAATGAAG
CGCTAGCCCAAGAGATCGCTTTTTTCCAAAACGCTATCGGTGGGGTTTTAGGCCCTCAAGACAGCTGGCTGTTGCAAAGA
GGGATTAAAACGCTAGCATTACGCATGCAAGCCCATCAAAAAAACGCCCTTTGCGTGGCTGAATTTTTAGAAAAACACCC
TAAAGTAGAAAAGGTTTATTACCCGGGCCTTCCCACTCACCCTAATTACGAGCTAGCCAAAGCCCAAATGCGTGGCTTTA
GCGGAATGCTCTCTTTCACCCTCAAAAATGACAGCGAGGCGACTCTTTTTGTAGAAAGCCTTAAGTTATTCATTTTAGGC
GAGAGCTTAGGCGGGGTGGAAAGCTTGGTGGGGATTCCGGTATTTATGACCCATGCGTGCATCCCTAAAGCGCAACGAGA
AGCTGCCGGGATTAGAGATGGCCTGGTGCGCTTGTCTGTAGGGATTGAGCATGAACAGGATTTGTTAGAAGATTTAGAGC
AAGCGTTCGCTAAAATTCGCTAA

Protein sequence :
MRMQTKLIHGGISEDATTGAVSVPIYQTSTYRQDAIGRHKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIHA
VFSLLQSGDHVLLGDDVYGGTFRLFNKVLVKNGLSCTIIDTSDLSQIKKAIKPNTKALYLETPSNPLLKITDLAQCASVA
KDHGLLTIVDNTFATPYYQNPLLLGADIVVHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQR
GIKTLALRMQAHQKNALCVAEFLEKHPKVEKVYYPGLPTHPNYELAKAQMRGFSGMLSFTLKNDSEATLFVESLKLFILG
ESLGGVESLVGIPVFMTHACIPKAQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFAKIR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-96 54
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-98 54
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 3e-72 47

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
K750_09475 YP_007982929.1 cystathionine beta-lyase BAC0207 Protein 2e-63 44