Gene Information

Name : K747_04095 (K747_04095)
Accession : YP_007979023.1
Strain : Helicobacter pylori UM032
Genome accession: NC_021215
Putative virulence/resistance : Virulence
Product : ATP synthase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1440961 - 1442265 bp
Length : 1305 bp
Strand : -
Note : Derived by automated computational analysis using gene prediction method: Protein Homology.

DNA sequence :
ATGCCCCTAAAATCCTTAAAAAACCGCTTGAATCAGCATTTTGATCTATCGCCTCGCTACGGGAGCGTGAAAAAAATCAT
GCCCAATATCGTTTATGCGGATGGTTTTAACCCGTCTGTGGGCGATGTGGTGAAGATTGAAAAAAGCGATGGCACTGAAT
GCGTGGGAATGGTGGTGGTGGCAGAAAAAGAGCAGTTTGGTTTCACGCCCTTTAATTTTATAGAGGGGGCTAGGGCTGGC
GATAAGGTGTTGTTTTTAAAAGAGGGATTGAATTTCCCTGTGGGCCGTAATCTTTTAGGGAGGGTGCTTAACCCTTTAGG
GCAAGTCATTGACAATAAGGGGGCTCTAGATTATGAGCGATTAGCGCCCGTGATTACAACGCCTATAGCCCCTTTAAAAA
GAGGCTTGATTGATGAGGTTTTTAGCGTGGGGGTGAAGAGCATTGATGGGCTTTTGACTTGCGGTAAGGGGCAAAAACTG
GGCATTTTTGCCGGCTCTGGGGTGGGTAAATCCACGCTAATGGGCATGATCACTAGGGGTTGCTTAGCGCCTATTAAAGT
GATCGCTTTGATTGGGGAAAGGGGCAGAGAAATCCCTGAATTTATAGAGAAAAACTTAAAAGGGGATTTAAGCTCTTGCG
TGTTGGTGGTTGCTACGAGCGATGATAGCCCTTTAATGCGCAAATACGGGGCCTTTTGCGCGATGAGCGTGGCGGAGTAT
TTTAAAAACCAGGGGCTAGATGTGTTATTCATCATGGATTCAGTAACTCGTTTCGCTATGGCTCAAAGAGAGATTGGTTT
AGCCTTAGGCGAACCGCCCACTTCCAAAGGCTACCCCCCATCCGCGCTTTCCTTATTGCCTCAATTAATGGAGAGAGCGG
GCAAGGAAGAAAATAAGGGGAGCATTACGGCTTTTTTTAGCGTGCTGGTAGAGGGCGATGATTTGAGCGATCCTATAGCC
GATCAGGCTAGGAGTATTTTAGACGGGCATATTGTCTTAAGCAGGGAATTAACCGATTATGGGATCTACCCGCCTATTAA
TATTTTAAACTCCGCATCAAGGGTGGCTAAAGACATCATTAGCGAGTCTCAAAACCTTTGTGCGAGAAAATTCCGCCGTT
TGTATGCGTTATTGAAAGAAAATGAAATGCTCATTCGCATCGGATCTTATCAAATGGGGAACGATAAAGAGCTTGATGAA
GCGATTAAGAAGAAGGCTTTAATGGAGCAATTTTTAGCGCAAGATGAAAACGCTTTACAGACTTTTGAACAAAGCTTTCA
GCAATTAGAAGAAATCTTAAAATAA

Protein sequence :
MPLKSLKNRLNQHFDLSPRYGSVKKIMPNIVYADGFNPSVGDVVKIEKSDGTECVGMVVVAEKEQFGFTPFNFIEGARAG
DKVLFLKEGLNFPVGRNLLGRVLNPLGQVIDNKGALDYERLAPVITTPIAPLKRGLIDEVFSVGVKSIDGLLTCGKGQKL
GIFAGSGVGKSTLMGMITRGCLAPIKVIALIGERGREIPEFIEKNLKGDLSSCVLVVATSDDSPLMRKYGAFCAMSVAEY
FKNQGLDVLFIMDSVTRFAMAQREIGLALGEPPTSKGYPPSALSLLPQLMERAGKEENKGSITAFFSVLVEGDDLSDPIA
DQARSILDGHIVLSRELTDYGIYPPINILNSASRVAKDIISESQNLCARKFRRLYALLKENEMLIRIGSYQMGNDKELDE
AIKKKALMEQFLAQDENALQTFEQSFQQLEEILK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 4e-73 50
escN CAC81862.1 EscN protein Virulence LEE II Protein 3e-77 46
escN NP_290268.1 hypothetical protein Virulence LEE Protein 3e-78 46
escN AAC38383.1 EscN Virulence LEE Protein 4e-78 46
ECs4568 NP_312595.1 EscN Virulence LEE Protein 3e-78 46
escN AAC31513.1 L0034 Virulence LEE Protein 2e-78 46
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 2e-78 46
unnamed AAL06369.1 EscN Virulence LEE Protein 4e-77 45
escN AAL57542.1 EscN Virulence LEE Protein 8e-77 45
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 5e-77 45
escN AAK26715.1 EscN Virulence LEE Protein 8e-77 45
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 2e-53 45
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 1e-53 45
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-81 44
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 3e-82 44
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-80 44
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 2e-81 44
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 2e-81 44
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-81 44
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 5e-80 44
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-70 44
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-70 44
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-79 43
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-79 43
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 5e-63 43
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 6e-63 43
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-63 43
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 2e-52 43
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 6e-59 43
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-52 43
escN YP_003236088.1 translocator EscN Virulence LEE Protein 5e-78 42
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 4e-59 42
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 2e-59 42
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 1e-58 42
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 3e-72 41
escN YP_003223475.1 translocator EscN Virulence LEE Protein 6e-77 41
escN CAI43874.1 EscN protein Virulence LEE Protein 4e-77 41
invC AAS66861.1 InvC Not tested SSR-2 Protein 6e-59 41
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 9e-53 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
K747_04095 YP_007979023.1 ATP synthase VFG0390 Protein 8e-79 52
K747_04095 YP_007979023.1 ATP synthase VFG0192 Protein 3e-77 51
K747_04095 YP_007979023.1 ATP synthase VFG0048 Protein 1e-78 50
K747_04095 YP_007979023.1 ATP synthase VFG2331 Protein 1e-71 49
K747_04095 YP_007979023.1 ATP synthase VFG2144 Protein 8e-78 47
K747_04095 YP_007979023.1 ATP synthase VFG0812 Protein 1e-78 46
K747_04095 YP_007979023.1 ATP synthase VFG0730 Protein 2e-78 46
K747_04095 YP_007979023.1 ATP synthase VFG1254 Protein 1e-77 45
K747_04095 YP_007979023.1 ATP synthase VFG0515 Protein 3e-63 43
K747_04095 YP_007979023.1 ATP synthase VFG1778 Protein 2e-55 42
K747_04095 YP_007979023.1 ATP synthase VFG1008 Protein 9e-60 41