Gene Information

Name : Tmari_0216 (Tmari_0216)
Accession : YP_007976567.1
Strain : Thermotoga maritima MSB8
Genome accession: NC_021214
Putative virulence/resistance : Virulence
Product : Flagellum-specific ATP synthase FliI
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 233420 - 234736 bp
Length : 1317 bp
Strand : -
Note : Corresponds to TM0218

DNA sequence :
TTGAAGGACATCCTGAAAGAGCTGAAAAAGAAGTTGAGTGAAGAAGATTTCAATAAATTCAACGGAAGAGTCACACGAGT
GGTAGGACTCACTGTGGAATCGAAAGGTCCAGACGCTTTTCTAGGAGAAATGTGTAAGATCTCACTTCAAAACGGTAAAA
ACGCACTCGCGGAGGTAGTTGGTTTCAGGGAAGAAAGTGTTATTCTCATGCCCTACGAGGATGTCTCCGGGTTGAAGATG
GGCTGTGAAGTCATCAGAACTAACAAAGTACTCGAAGTTGGTGTCAGCAGAAAGATGATCGGAAGGGTGTTCGATGGTCT
GGGACGTCCAATAGACGGAAAGCCCTTCGTTCCGGAAGACAGATATCCTCTGATCAACAACCCTCCAAACCCTCTAAAAA
GACGAAGAATAAAAGATCCTTTACCGGTGGGTATACGATCAATAGATGGTTTCATAACCATAGGCAAAGGCCAGAGAATT
GGAATTTTCGCGGGCAGCGGTGTTGGAAAAAGCACACTTCTTGGAATGATCGCACGAAACACGACGGCGGACATTAACGT
GCTGGCCCTCATCGGGGAGCGCGGAAGAGAGGTCAGGGAATTCATAGAGAGGGACCTTGGAGAGGAGGGACTGAAGCGAT
CTATACTGGTGGTCTCAACTTCCGATCAGCCTGCCCTTGCCAGAGTGAAATCTCTCCTCACCGCCACCAGTATAGCGGAA
TTCTTCAGAGATCTGGGATACGATGTCCTTCTGATGGTGGACTCTCTCACCAGATGGGCCATGGCTCAGAGAGAAGTGGG
GCTCGCAGTGGGAGAACCTCCCACCACCAGGGGATATCCACCAAGTGTCTTTGCCGGCCTTCCAAAAATACTCGAAAGGG
CAGGAAACTCAGATAAAGGCAGCATAACAGCGATTTACACCGTGCTCGTTGAAGCGGACGACTTCAACGAACCCATTTCC
GACACTGTCAGATCCATCGTAGATGGACACATAATTCTTTCGAGGAGACTTGCCGAATCGAATCACTACCCAGCAGTCGA
TGTTCTTGCAAGTGTGAGCCGATTGATGAACGATATCGTCACCGAAGAACACAGAGAGGCGGCGAACCGCCTCCGATCGC
TGATGTCGGCTTATGAATCCGCAAAAGATCTGATTGAAATCGGTGCTTACAAGAGTGGGACCAATCCACTCGTTGACAAA
GCTGTGGAAATGAAAGACGAGATCGATTCCTTTCTGAAACAGGGTGTCTTTGAAAAAGCTTCATTCGAGGAAACCCTTCA
GAAACTTCTGGATCTATACCTGAGATCTCTTGACTAA

Protein sequence :
MKDILKELKKKLSEEDFNKFNGRVTRVVGLTVESKGPDAFLGEMCKISLQNGKNALAEVVGFREESVILMPYEDVSGLKM
GCEVIRTNKVLEVGVSRKMIGRVFDGLGRPIDGKPFVPEDRYPLINNPPNPLKRRRIKDPLPVGIRSIDGFITIGKGQRI
GIFAGSGVGKSTLLGMIARNTTADINVLALIGERGREVREFIERDLGEEGLKRSILVVSTSDQPALARVKSLLTATSIAE
FFRDLGYDVLLMVDSLTRWAMAQREVGLAVGEPPTTRGYPPSVFAGLPKILERAGNSDKGSITAIYTVLVEADDFNEPIS
DTVRSIVDGHIILSRRLAESNHYPAVDVLASVSRLMNDIVTEEHREAANRLRSLMSAYESAKDLIEIGAYKSGTNPLVDK
AVEMKDEIDSFLKQGVFEKASFEETLQKLLDLYLRSLD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 4e-103 53
escN YP_003236088.1 translocator EscN Virulence LEE Protein 3e-90 50
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 3e-90 50
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-98 50
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-98 50
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 9e-99 50
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 9e-99 50
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-97 50
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 1e-97 50
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 1e-98 50
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-85 49
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-85 49
escN AAK26715.1 EscN Virulence LEE Protein 3e-90 49
escN AAL57542.1 EscN Virulence LEE Protein 3e-90 49
escN CAC81862.1 EscN protein Virulence LEE II Protein 3e-90 49
escN CAI43874.1 EscN protein Virulence LEE Protein 2e-90 49
unnamed AAL06369.1 EscN Virulence LEE Protein 1e-87 49
escN NP_290268.1 hypothetical protein Virulence LEE Protein 2e-89 49
ECs4568 NP_312595.1 EscN Virulence LEE Protein 2e-89 49
escN AAC31513.1 L0034 Virulence LEE Protein 1e-89 49
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 1e-89 49
escN AAC38383.1 EscN Virulence LEE Protein 8e-90 49
escN YP_003223475.1 translocator EscN Virulence LEE Protein 2e-90 49
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-96 49
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-96 49
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-86 49
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-87 49
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 3e-87 49
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-87 49
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 1e-86 49
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 4e-91 48
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 3e-88 48
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 4e-83 47
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 6e-79 47
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-84 47
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 2e-85 47
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 2e-85 47
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 2e-80 45
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 6e-82 45
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 5e-82 45
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 1e-82 45
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 2e-80 45
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 8e-87 45
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 2e-67 43
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-67 41
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 2e-67 41
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-67 41
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-67 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tmari_0216 YP_007976567.1 Flagellum-specific ATP synthase FliI VFG0192 Protein 4e-105 53
Tmari_0216 YP_007976567.1 Flagellum-specific ATP synthase FliI VFG0390 Protein 1e-101 53
Tmari_0216 YP_007976567.1 Flagellum-specific ATP synthase FliI VFG2144 Protein 6e-102 53
Tmari_0216 YP_007976567.1 Flagellum-specific ATP synthase FliI VFG1254 Protein 9e-94 51
Tmari_0216 YP_007976567.1 Flagellum-specific ATP synthase FliI VFG0048 Protein 2e-99 50
Tmari_0216 YP_007976567.1 Flagellum-specific ATP synthase FliI VFG2331 Protein 1e-92 49
Tmari_0216 YP_007976567.1 Flagellum-specific ATP synthase FliI VFG0730 Protein 5e-90 49
Tmari_0216 YP_007976567.1 Flagellum-specific ATP synthase FliI VFG0812 Protein 8e-90 49
Tmari_0216 YP_007976567.1 Flagellum-specific ATP synthase FliI VFG0515 Protein 2e-87 49
Tmari_0216 YP_007976567.1 Flagellum-specific ATP synthase FliI VFG2499 Protein 8e-89 48
Tmari_0216 YP_007976567.1 Flagellum-specific ATP synthase FliI VFG1008 Protein 3e-68 42
Tmari_0216 YP_007976567.1 Flagellum-specific ATP synthase FliI VFG2459 Protein 1e-76 42
Tmari_0216 YP_007976567.1 Flagellum-specific ATP synthase FliI VFG0555 Protein 8e-68 41
Tmari_0216 YP_007976567.1 Flagellum-specific ATP synthase FliI VFG1778 Protein 6e-71 41