Gene Information

Name : clpA (TL13_1778)
Accession : YP_007976128.1
Strain : Streptococcus suis TL13
Genome accession: NC_021213
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit ClpA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1801647 - 1804100 bp
Length : 2454 bp
Strand : -
Note : -

DNA sequence :
ATGAAAATTTCAACTGGTTTACAGCGGGTTTTTGAAGATGCCCAGTTAGTGGCCCAACGTTATGCCTGTGATTACTTGGA
AACCTGGCATGTTCTCTTGTCTTTCGTTATCAACCATGATACAGTCGCTGGCGCTGTTTTGGCAGAATATCCTATTTCAA
TTTCTGACTATGAACATGCAACTTTTGTTGTGACCGACAAGGTCTATCGTGAAGAGTTGGATAGTTTTCGTATTTTACCA
TCTTCTAAACGTTTGGATGAAACAGCTAGTTTTGCCAAGAAAATTGCAGAAGTCGTCAAGGCTAAGGAGCTGGGAACGGA
ACATTTGTTTATGGCTATGTTGTTGGACAAGCGGTCAACAGCTAGTCAGATTTTGGACAAGGTAGGTTTTTATTTTGAAG
ACTCAGATGATAAGTTTCGTTTCTTGGATTTGCGTAAAAACTTGGAGGCACGTGCGGGATTTACCAAAGAGGACCTTAAA
GCTATCCGCAGTGTGATGAAGGGTGGCAAAGCCAAACCTACCAATATGGGACAGATGATGGGAATGCCCCCAGCACCTCA
AAGTGGTGGATTAGAAGACTACACTCGTGATTTGACAGCTTTGGCGCGTGAAGGGAAGATTGAACCTGTCATCGGTCGAG
ACGCTGAGATTGCACGGATGATCCAAATTCTATCACGTAAAACCAAGAACAACCCAGTTCTAGTTGGTGATGCTGGTGTC
GGAAAAACTGCGCTTGCTTTGGGTCTTGCTCAACGTGTTGCTGCAGGTGATGTCCCTGTCAGCTTGGCTAAGATGCGGGT
TTTGGAACTTGACTTGATGAACGTTATCGCTGGAACTCGTTTCCGGGGTGATTTCGAAGAGCGGATGAATAATATCATCA
ATGACATCGAGGAAGATGGTCAGGTCATCCTTTTCATCGATGAGTTGCATACCATTATGGGTTCTGGCTCGGGGATTGAT
TCAACCTTGGATGCAGCCAATATCCTCAAACCAGCTCTTGCTCGTGGCACCCTCCGTACGGTCGGAGCGACGACTCAGAC
AGAATACCAAAAGCATATTGAGAAAGACGCAGCCTTGGTTCGCCGTTTTGCCAAAGTGACCATTGAAGAGCCGACAGTTG
AGGACAGTATTGCCATTTTGACAGGGCTTAAAGGTACTTTTGAGAAATACCACAGGGTCCGTATTGGACAAGCAGCTGTA
GAGACTGCTGTGACCTACGCTAAGCGGTATTTGACTAGTAAAAACCTGCCAGATTCAGCCATTGATTTGCTGGATGAAGC
CAGTGCAACGGTACAAAATCGAGTGAAAGGGCAGGCTGAGGAAACAGGACTGACGAGCATAGACAAGGCCTTGATGGATA
AAAAATATAAGACTGTCAGCAAGCTTTTGATTAAAACGAAAGAAGATGCCGAGGCTAGTCAAAACTATGACCTTGAAGTA
ACAGAAGAAGATGTTTTAGAAACACTTAGCCGCTTATCAGGTATCCCAGTAGCCAAGCTTAGCCAATCAGATACTAAGAA
GTATCTGAATCTGGAAGCAGAATTGCACAAGCGTGTGATTGGGCAGGAAGAAGCTATTTCTGCAGTTAGCAGAGCTATTC
GCCGTAATCAGTCAGGTATTCGTACAGGTCGCAGACCGATTGGTTCCTTTATGTTCTTGGGACCAACTGGTGTCGGTAAG
ACAGAACTTGCTAAAGCCTTGGCAGAAGTTCTCTTTGATGACGAATCTGCTCTTATCCGTTTTGATATGTCTGAATACAT
GGAGAAATTCGCGGCCAGCCGTCTCAATGGAGCGCCTCCAGGCTACGTGGGCTATGAAGAAGGTGGCGAATTGACGGAAA
AAGTTCGTAATAAACCTTATTCTGTTCTTCTTTTTGATGAGGTTGAAAAGGCTCATACAGATATTTTCAATGTTCTCTTG
CAGGTCTTGGATGATGGTGTTCTGACAGACAGTAAGGGACGTAAGGTTGATTTCTCAAATACCATTATTATCATGACGTC
AAACCTTGGAGCAACAGCTCTTCGTGATGATAAGACAGTTGGTTTTGGTGCCCTTGATTTATCTAAGGACCATAAGGAAG
TGGAGAAACGCATTTTTGAGGAATTGAAAAAAGCCTATCGTCCAGAATTTATCAACCGTATTGACGAGAAAGTTGTCTTC
CATAGCCTAACGGAAACTCATATGCAGGATGTTGTCAAGGTCATGATTAAACCTTTGTTGGCTGTAACAGCTGAGAAAGG
AATTACCCTTAAACTTCAACCATCAGCCTTTAAGTTATTGGCTAAACAAGGTTACGACCCAGAAATGGGGGCTCGTCCTC
TTCGTAGACTCTTACAAACCAAATTGGAAGATCCGTTAGCAGAAATGTTGCTCCGTGGTGACTTGGCTACTGGTTCGACC
TTGAAGGTTGGGGTCAAGGGCGAAGAACTCAAGTTTGATGTGGTAAAGGGATAA

Protein sequence :
MKISTGLQRVFEDAQLVAQRYACDYLETWHVLLSFVINHDTVAGAVLAEYPISISDYEHATFVVTDKVYREELDSFRILP
SSKRLDETASFAKKIAEVVKAKELGTEHLFMAMLLDKRSTASQILDKVGFYFEDSDDKFRFLDLRKNLEARAGFTKEDLK
AIRSVMKGGKAKPTNMGQMMGMPPAPQSGGLEDYTRDLTALAREGKIEPVIGRDAEIARMIQILSRKTKNNPVLVGDAGV
GKTALALGLAQRVAAGDVPVSLAKMRVLELDLMNVIAGTRFRGDFEERMNNIINDIEEDGQVILFIDELHTIMGSGSGID
STLDAANILKPALARGTLRTVGATTQTEYQKHIEKDAALVRRFAKVTIEEPTVEDSIAILTGLKGTFEKYHRVRIGQAAV
ETAVTYAKRYLTSKNLPDSAIDLLDEASATVQNRVKGQAEETGLTSIDKALMDKKYKTVSKLLIKTKEDAEASQNYDLEV
TEEDVLETLSRLSGIPVAKLSQSDTKKYLNLEAELHKRVIGQEEAISAVSRAIRRNQSGIRTGRRPIGSFMFLGPTGVGK
TELAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHTDIFNVLL
QVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGALDLSKDHKEVEKRIFEELKKAYRPEFINRIDEKVVF
HSLTETHMQDVVKVMIKPLLAVTAEKGITLKLQPSAFKLLAKQGYDPEMGARPLRRLLQTKLEDPLAEMLLRGDLATGST
LKVGVKGEELKFDVVKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 5e-137 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpA YP_007976128.1 ATP-dependent Clp protease ATP-binding subunit ClpA VFG0079 Protein 1e-152 53
clpA YP_007976128.1 ATP-dependent Clp protease ATP-binding subunit ClpA VFG0080 Protein 5e-119 45