Gene Information

Name : pyk (GBS222_0786)
Accession : YP_007968552.1
Strain : Streptococcus agalactiae 2-22
Genome accession: NC_021195
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 836138 - 837640 bp
Length : 1503 bp
Strand : +
Note : -

DNA sequence :
ATGAATAAACGCGTAAAAATCGTTGCAACACTTGGTCCTGCGGTAGAATTCCGTGGTGGTAAGAAGTTTGGTGAGTCTGG
ATACTGGGGTGAAAGCCTTGACGTAGAAGCTTCAGCAGAAAAAATTGCTCAATTGATTAAAGAAGGTGCTAACGTTTTCC
GTTTCAACTTCTCACATGGAGATCATGCTGAGCAAGGAGCTCGTATGGCTATTGTTCGTAAAGCAGAAGAGATTGCAGGA
CAAAAAGTTGGCTTCCTCCTTGATACTAAAGGACCTGAAATTCGTACAGAACTTTTTGAAGATGGTGCAGATTTCCATTC
ATATACAACAGGTACAAAATTACGTGTTGCTACTAAGCAAGGTATCAAATCAACTCCAGAAGTGATTGCATTGAATGTTG
CTGGTGGACTTGACATCTTTGATGACGTTGAAGTTGGTAAGCAAATCCTTGTTGATGATGGTAAACTAGGTCTTACTGTG
TTTGCAAAAGATAAAGACACTCGTGAATTTGAAGTAGTTGTTGAGAATGATGGCCTTATTGGTAAACAAAAAGGTGTAAA
CATCCCTTATACTAAAATTCCTTTCCCTGCACTTGCAGAACGCGATAATGCTGATATCCGTTTTGGACTTGAGCAAGGAC
TTAACTTTATTGCTATCTCATTTGTACGTACTGCTAAAGATGTTAATGAAGTTCGTGCTATTTGTGAAGAAACTGGCAAT
GGACACGTTAAGTTGTTTGCTAAAATTGAAAATCAACAAGGTATCGATAGTATTGATGAGATTATCGAAGCAGCAGATGG
TATTATGATTGCTCGTGGTGATATGGGTATCGAAGTTCCATTTGAAATGGTTCCAGTTCACCAAAAAATGATCATTACTA
AAGTTAATGCAGCTGGTAAAGCAGTTATTACAGCAACAAATATGCTTGAAACAATGACTGATAAACCACGTGCGACTCGT
TCAGAAGTATCTGATGTCTTCAATGCTGTTATTGATGGTACTGATGCTACAATGCTTTCAGGTGAGTCAGCTAATGGTAA
ATACCCAGTTGAGTCAGTTCGTACAATGGCTACTATTGATAAAAATGCTCAAACATTACTCAATGAGTATGGTCGCTTAG
ACTCATCTGCATTCCCACGTAATAACAAAACTGATGTTATTGCATCTGCGGTTAAAGATGCAACACACTCAATGGATATC
AAACTTGTTGTAACAATTACTGAAACAGGTAATACAGCTCGTGCCATTTCTAAATTCCGTCCAGATGCAGACATTTTGGC
TGTTACATTTGATGAAAAAGTACAACGTTCATTGATGATTAACTGGGGCGTTATCCCTGTCCTTGCAGACAAACCAGCAT
CTACAGATGATATGTTTGAAGTTGCAGAACGTGTAGCACTTGAAGCAGGACTTGTTGAATCAGGCGATAATATCGTTATC
GTTGCAGGTGTTCCTGTAGGTACAGGTGGAACTAACACAATGCGTGTTCGTACTGTTAAATAA

Protein sequence :
MNKRVKIVATLGPAVEFRGGKKFGESGYWGESLDVEASAEKIAQLIKEGANVFRFNFSHGDHAEQGARMAIVRKAEEIAG
QKVGFLLDTKGPEIRTELFEDGADFHSYTTGTKLRVATKQGIKSTPEVIALNVAGGLDIFDDVEVGKQILVDDGKLGLTV
FAKDKDTREFEVVVENDGLIGKQKGVNIPYTKIPFPALAERDNADIRFGLEQGLNFIAISFVRTAKDVNEVRAICEETGN
GHVKLFAKIENQQGIDSIDEIIEAADGIMIARGDMGIEVPFEMVPVHQKMIITKVNAAGKAVITATNMLETMTDKPRATR
SEVSDVFNAVIDGTDATMLSGESANGKYPVESVRTMATIDKNAQTLLNEYGRLDSSAFPRNNKTDVIASAVKDATHSMDI
KLVVTITETGNTARAISKFRPDADILAVTFDEKVQRSLMINWGVIPVLADKPASTDDMFEVAERVALEAGLVESGDNIVI
VAGVPVGTGGTNTMRVRTVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-70 44
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-70 44
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-70 44
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-71 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_007968552.1 pyruvate kinase VFG0479 Protein 5e-71 44