Gene Information

Name : J114_02250 (J114_02250)
Accession : YP_007964277.1
Strain : Mycobacterium tuberculosis EAI5/NITR206
Genome accession: NC_021194
Putative virulence/resistance : Unknown
Product : phosphomethylpyrimidine synthase ThiC
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 508492 - 510135 bp
Length : 1644 bp
Strand : -
Note : COG0422 Thiamine biosynthesis protein ThiC

DNA sequence :
ATGACCATCACCGTTGAACCGTCGGTGACCACGGGTCCCATCGCGGGCAGCGCCAAGGCCTACCGTGAAATCGAGGCTCC
CGGCAGCGGAGCTACTCTCCAAGTCCCGTTTCGACGGGTGCACTTGTCCACCGGAGACCACTTCGACCTCTACGACACCT
CCGGGCCCTACACCGACACGGACACGGTGATCGACCTGACCGCGGGGCTGCCGCATAGGCCCGGAGTGGTTCGCGATCGG
GGCACCCAGCTGCAGCGGGCCCGCGCCGGGGAGATCACCGCCGAGATGGCGTTCATCGCCGCCCGCGAAGACATGTCCGC
CGAGCTAGTGCGCGACGAGGTCGCCCGCGGCCGCGCGGTGATCCCGGCCAACCACCACCACCCCGAGAGCGAGCCGATGA
TCATCGGCAAGGCGTTCGCGGTGAAAGTCAACGCCAACATCGGCAACTCGGCGGTGACGAGCTCGATCGCCGAGGAGGTC
GACAAGATGGTGTGGGCCACCCGCTGGGGGGCCGACACCATCATGGACCTGTCCACCGGCAAGAACATCCACGAAACCCG
CGAGTGGATCCTGCGCAATTCTCCCGTGCCGGTCGGCACCGTGCCGATCTATCAGGCGCTGGAGAAAGTCAAGGGCGATC
CGACCGAGCTGACCTGGGAGATCTACCGCGACACCGTGATCGAGCAGTGTGAGCAAGGCGTGGACTACATGACGGTGCAC
GCCGGGGTGCTGCTGCGGTATGTGCCGCTGACCGCCAAGCGGGTCACCGGCATCGTGTCCCGCGGGGGTTCGATCATGGC
CGCGTGGTGTTTGGCACATCATCGGGAGTCGTTCTTGTACACCAACTTTGAGGAGCTCTGCGATATTTTCGCCCGCTACG
ACGTCACCTTCTCACTCGGTGACGGGCTGCGACCAGGGTCGATCGCTGATGCCAACGACGCCGCGCAGTTCGCCGAGCTG
CGCACCCTGGGCGAGCTCACCAAGATCGCCAAAGCCCATGGCGCACAGGTGATGATCGAGGGGCCGGGCCATATCCCAAT
GCACAAGATCGTCGAGAATGTGCGGCTGGAAGAGGAACTGTGTGAGGAGGCCCCGTTCTACACGCTGGGTCCGCTGGCCA
CCGACATCGCGCCGGCCTACGACCACATCACCTCGGCGATCGGTGCGGCCATCATCGCCCAAGCCGGTACCGCGATGCTG
TGCTACGTCACCCCCAAGGAGCACCTCGGGTTGCCGGACCGCAAGGACGTCAAGGACGGGGTGATCGCCTACAAGATCGC
CGCGCATGCGGCCGATTTGGCCAAGGGCCATCCGCGCGCCCAGGAGCGCGACGACGCTTTGAGCACGGCGCGTTTCGAGT
TCCGCTGGAACGACCAGTTCGCACTGTCGCTGGATCCCGACACCGCACGGGAATTCCACGACGAAACCCTGCCGGCGGAG
CCGGCCAAGACCGCGCACTTCTGCTCGATGTGCGGACCGAAGTTCTGCTCCATGCGCATCACCCAGGACGTCCGTGAGTA
CGCCGCCGAACACGGGCTTGAGACCGAAGCGGACATCGAAGCCGTGCTCGCCGCCGGAATGGCCGAAAAGTCACGTGAAT
TCGCAGAGCACGGCAATCGGGTGTATCTCCCGATAACCCAGTGA

Protein sequence :
MTITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTVIDLTAGLPHRPGVVRDR
GTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAVIPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEV
DKMVWATRWGADTIMDLSTGKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH
AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLGDGLRPGSIADANDAAQFAEL
RTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEELCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAML
CYVTPKEHLGLPDRKDVKDGVIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAE
PAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNRVYLPITQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 4e-155 68
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 4e-155 68