Gene Information

Name : J113_03265 (J113_03265)
Accession : YP_007960355.1
Strain : Mycobacterium tuberculosis CAS/NITR204
Genome accession: NC_021193
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 548171 - 549691 bp
Length : 1521 bp
Strand : +
Note : COG1012 NAD-dependent aldehyde dehydrogenases

DNA sequence : 
ATGACTGTCTTTTCCCGTCCCGGTTCCGCCGGGGCGCTGATGTCCTATGAATCCCGGTACCAAAACTTCATCGGGGGCCA
GTGGGTCGCGCCGGTCCATGGGCGCTACTTCGAGAACCCGACGCCGGTGACCGGCCAGCCGTTCTGCGAGGTGCCGCGCT
CCGACGCGGCCGACATCGACAAGGCGCTCGACGCCGCGCACGCGGCGGCGCCGGGGTGGGGCAAGACCGCACCGGCCGAA
CGGGCGGCGATCCTCAACATGATTGCCGACCGCATCGACAAGAACGCCGCCGCGCTGGCGGTGGCCGATCTGGGACAACG
GGAAACCGGTCCGGGAAGCGCTGGCCGCCGATATCCCGTTGGCGGTCGATCACTTCGCGGTACTTCGCCGCGGCATTCCG
CCCAGGAGGGCGCGCTGAGCCAGATCGACGAGGACACCGTGGCCTACCACTTCCACGAGCCGCTCGGCGTGGTGGGCCAG
ATCATTCCGTGGAACTTCCCCATCCTGATGGCGGCCTGGAAGCTGGCGCCGGCGTTGGCGGCCGGCAACACGGCGGTGCT
CAAACCCGCCGAGCAGACACCCGCTTCGGTGCTCTACCTGATGTCGCTGATCGGTGATCTGTTGCCGCCCGGGGTGGTCA
ACGTGGTCAACGGATTCGGCGCCGAGGCCGGCAAGCCGTTGGCCTCCAGCGACCGCATCGCCAAGGTCGCGTTCACCGGG
GAAACCACCACGGGGCGGCTGATCATGCAATACGCCTCGCACAACCTGATCCCGGTCACCCTGGAACTCGGCGGCAAGAG
CCCCAACATCTTCTTCGCCGACGTGCTGGCCGCCCACGACGACTTCTGCGACAAGGCGCTGGAAGGCTTCACCATGTTCG
CCCTCAACCAGGGCGAGGTGTGCACCTGCCCGTCGCGCAGTCTGATCCAGGCCGACATCTACGACGAGTTCCTGGAGCTG
GCGGCGATCCGGACCAAGGCGGTCCGGCAGGGCGACCCGCTGGACACCGAAACCATGCTGGGTTCCCAGGCCTCCAACGA
CCAGCTGGAAAAGGTGTTGTCCTACATCGAAATCGGCAAGCAAGAGGGTGCGGTGATTATCGCCGGAGGCGAGCGCGCCG
AACTAGGCGGCGACCTGTCCGGCGGTTATTACATGCAGCCGACGATCTTCACCGGCACCAACAACATGCGGATTTTCAAG
GAGGAGATCTTCGGGCCGGTGGTCGCGGTGACGTCGTTCACCGATTACGACGACGCGATCGGCATCGCCAACGACACCCT
CTACGGCTTGGGTGCCGGTGTGTGGAGCCGCGACGGCAACACTGCCTATCGGGCCGGGCGGGACATCCAGGCCGGCCGGG
TGTGGGTCAACTGCTACCACCTCTACCCCGCGCACGCGGCGTTCGGCGGCTACAAGCAGTCCGGCATCGGCCGGGAGGGC
CACCAGATGATGCTGCAGCACTACCAGCACACCAAGAACCTGCTGGTGTCCTACTCGGATAAGGCGCTGGGGTTCTTCTG
A

Protein sequence : 
MTVFSRPGSAGALMSYESRYQNFIGGQWVAPVHGRYFENPTPVTGQPFCEVPRSDAADIDKALDAAHAAAPGWGKTAPAE
RAAILNMIADRIDKNAAALAVADLGQRETGPGSAGRRYPVGGRSLRGTSPRHSAQEGALSQIDEDTVAYHFHEPLGVVGQ
IIPWNFPILMAAWKLAPALAAGNTAVLKPAEQTPASVLYLMSLIGDLLPPGVVNVVNGFGAEAGKPLASSDRIAKVAFTG
ETTTGRLIMQYASHNLIPVTLELGGKSPNIFFADVLAAHDDFCDKALEGFTMFALNQGEVCTCPSRSLIQADIYDEFLEL
AAIRTKAVRQGDPLDTETMLGSQASNDQLEKVLSYIEIGKQEGAVIIAGGERAELGGDLSGGYYMQPTIFTGTNNMRIFK
EEIFGPVVAVTSFTDYDDAIGIANDTLYGLGAGVWSRDGNTAYRAGRDIQAGRVWVNCYHLYPAHAAFGGYKQSGIGREG
HQMMLQHYQHTKNLLVSYSDKALGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 6e-111 56
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 4e-118 55
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 4e-118 55
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 4e-118 55
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-117 55
aldA ACK75577.1 aldehyde dehydrogenase Not tested VPI Protein 2e-67 51
aldA ACK75588.1 aldehyde dehydrogenase Not tested VPI Protein 1e-66 51
aldA ACK75585.1 aldehyde dehydrogenase Not tested VPI Protein 7e-67 51
aldA ACK75593.1 aldehyde dehydrogenase Not tested VPI Protein 7e-67 51
aldA ACK75574.1 aldehyde dehydrogenase Not tested VPI Protein 3e-67 51
aldA ACK75590.1 aldehyde dehydrogenase Not tested VPI Protein 3e-67 51
aldA ACK75596.1 aldehyde dehydrogenase Not tested VPI Protein 3e-67 51
aldA ACK75582.1 aldehyde dehydrogenase Not tested VPI Protein 2e-67 51
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 8e-53 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
J113_03265 YP_007960355.1 aldehyde dehydrogenase VFG0082 Protein 2e-111 56