Gene Information

Name : J113_25180 (J113_25180)
Accession : YP_007963499.1
Strain : Mycobacterium tuberculosis CAS/NITR204
Genome accession: NC_021193
Putative virulence/resistance : Virulence
Product : ATP-dependent protease ATP-binding subunit clpC1
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4020492 - 4022528 bp
Length : 2037 bp
Strand : -
Note : COG0542 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
GTGTCGACCAGTTCGGCCCAACCTCCGGCGGCGGCGATGGAAGGCAAACTGGACCCGGTCATCGGCCGCGAGAAGGAAAT
CGAGCGGGTCATGCAGGTGCTCTCTCGGCGCACCAAGAACAACCCGGTGCTGATCGGCGAGCCCGGCGTCGGCAAGACCG
CGGTCGTCGAAGGACTGGCGCAGGCCATCGTGCACGGCGAGGTGCCCGAGACGCTCAAGGACAAGCAGCTCTACACGCTG
GATCTGGGATCGCTGGTGGCGGGTAGCCGCTACCGCGGTGACTTCGAGGAACGCCTCAAGAAGGTGCTCAAGGAGATCAA
CACCCGCGGTGACATCATCCTGTTTATCGACGAGCTGCACACCTTGGTCGGTGCTGGAGCCGCCGAGGGCGCGATCGACG
CCGCCTCGATCCTGAAACCGAAGCTCGCTCGCGGTGAACTGCAAACGATCGGCGCCACCACGCTCGACGAATACCGCAAG
TACATCGAGAAGGACGCCGCGCTGGAGCGCCGCTTCCAGCCGGTGCAGGTGGGTGAGCCGACGGTGGAGCACACCATCGA
GATCCTCAAGGGCCTGCGGGACCGGTACGAGGCGCACCACCGGGTGTCGATCACCGATGCGGCGATGGTGGCCGCCGCGA
CCCTGGCCGACCGCTACATCAACGACCGGTTCCTGCCCGACAAGGCGATCGACCTGATCGACGAGGCGGGTGCTCGGATG
CGGATTCGTCGCATGACCGCACCGCCAGACCTACGCGAGTTCGATGAGAAGATCGCCGAGGCTCGTCGGGAGAAGGAATC
GGCTATCGACGCCCAGGACTTCGAGAAGGCCGCCAGCCTGCGCGACCGGGAGAAGACACTGGTCGCACAGCGTGCTGAGC
GCGAAAAGCAGTGGCGTTCAGGCGATCTTGACGTGGTCGCGGAGGTCGACGACGAGCAGATCGCCGAGGTGCTGGGCAAC
TGGACCGGTATCCCGGTGTTCAAGCTCACCGAGGCCGAGACCACCCGGCTGTTGCGGATGGAAGAAGAGCTGCACAAGCG
GATCATCGGGCAAGAGGACGCCGTCAAGGCCGTTTCCAAGGCCATCCGGCGTACCCGGGCCGGGCTGAAAGACCCCAAGC
GCCCGTCGGGCTCGTTCATCTTCGCCGGCCCGTCCGGTGTCGGTAAGACCGAACTGTCCAAGGCGCTGGCCAACTTCTTG
TTCGGTGACGACGACGCGCTTATTCAGATTGACATGGGTGAATTCCACGACCGGTTCACCGCGTCGCGGCTATTCGGCGC
GCCGCCCGGATACGTCGGCTACGAGGAGGGCGGCCAACTCACCGAGAAGGTGCGGCGCAAGCCGTTCTCGGTGGTGCTGT
TCGACGAGATCGAGAAGGCGCATCAGGAGATCTACAACAGCCTGCTGCAGGTGCTCGAGGATGGCCGGCTCACCGACGGG
CAGGGCCGCACGGTGGACTTCAAGAACACCGTGCTGATCTTTACGTCCAATCTGGGCACCTCCGACATCTCTAAGCCGGT
CGGTCTGGGCTTTTCCAAGGGCGGCGGTGAGAACGACTACGAGCGGATGAAACAGAAGGTCAACGACGAGCTGAAGAAAC
ACTTCCGCCCGGAGTTCCTCAACCGCATCGACGACATCATCGTCTTCCACCAGCTGACCCGCGAGGAGATCATCCGGATG
GTCGACCTGATGATCAGCCGGGTCGCCGGCCAGCTCAAGAGCAAGGACATGGCGCTGGTGCTGACCGATGCGGCCAAGGC
GCTGCTGGCCAAGCGTGGCTTCGACCCGGTGTTGGGGGCCCGCCCGTTGCGGCGCACCATCCAGCGTGAGATCGAAGATC
AGCTCTCGGAGAAGATCCTCTTCGAGGAGGTCGGGCCGGGTCAGGTGGTCACCGTGCACGTGGACAACTGGGATCGTGAA
GGTCCCGGCGAGGACGCGGTGTTCACCTTCACCGGTACCCGCAAGCCGCCGGCCGAGCCGGATCTGGCCAAGGCCTATGC
CATCCGCGCGGGCGGCCCGGAGCCGGCCGCGCGGTAG

Protein sequence :
MSTSSAQPPAAAMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTL
DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTIGATTLDEYRK
YIEKDAALERRFQPVQVGEPTVEHTIEILKGLRDRYEAHHRVSITDAAMVAAATLADRYINDRFLPDKAIDLIDEAGARM
RIRRMTAPPDLREFDEKIAEARREKESAIDAQDFEKAASLRDREKTLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGN
WTGIPVFKLTEAETTRLLRMEEELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKTELSKALANFL
FGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG
QGRTVDFKNTVLIFTSNLGTSDISKPVGLGFSKGGGENDYERMKQKVNDELKKHFRPEFLNRIDDIIVFHQLTREEIIRM
VDLMISRVAGQLKSKDMALVLTDAAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQVVTVHVDNWDRE
GPGEDAVFTFTGTRKPPAEPDLAKAYAIRAGGPEPAAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 83

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
J113_25180 YP_007963499.1 ATP-dependent protease ATP-binding subunit clpC1 VFG0079 Protein 0.0 61
J113_25180 YP_007963499.1 ATP-dependent protease ATP-binding subunit clpC1 VFG0080 Protein 2e-136 50