Gene Information

Name : Desgi_2314 (Desgi_2314)
Accession : YP_007945409.1
Strain : Desulfotomaculum gibsoniae DSM 7213
Genome accession: NC_021184
Putative virulence/resistance : Resistance
Product : copper/silver-translocating P-type ATPase,heavy metal-translocating P-type ATPase, Cd/Co/Hg/Pb/Zn-transporting
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2335883 - 2338141 bp
Length : 2259 bp
Strand : -
Note : PFAM: E1-E2 ATPase; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy

DNA sequence :
ATGACACAATGTTCAGGACATAATTGCAGTTGTGTAAAAAATAATATCATGGAGGAATTGACGTCGGAAGGATTGCAACA
ACCGATGAAAGTGACAAAGCCGGAGGAGAAGGCAATAAATAATTCAGCCCCACATCTAAATGGTATGCAAAAATCCGTTT
TCGTTTTACATGGTTTAGATTGTGCTGACTGCGCTGCTAAACTGGAAAAAAGAATTGCCGGGCTGTCAGGAGTGGAGGAG
GCCACAATTAATTTTGGGGCCTCCAAAATGAGCGTCCGGCACACCACCGGTGTGCCGCAAATTCTGCGTGCCATCAAGGA
GGCGGGTTACGCGGCAGAGTCTGACCATGCCGCAGCGACACAAACCAATCAACCGCTCTGGCATGACCCTAAGTTAATAT
TGACGGTTATATCCGGCTTGTTTTTAGCCGGAGGAATGACAGCGTCATTATTTAACTTGGGGGACCGGCTGGTCATAGAC
CTATTGCTGGCTGCCATGTTGTCAGGCGGTTACTTTGTGGTCAAAAACGACCTATACTCTATCAAGGCGTTAAGCTTGGA
CATGAATGTGCTGATGAGCGTGGCTGCCATAGGGGCCGTTGCCATCGGTGAGTGGTTTGAGGGAGCCACGGTGGTGTTCC
TTTTCTCCCTGGGTAATACCCTGCAGGCCTACAGCATGGCTAAAACAAGGTCGTCCATTCGGGCACTGATGGAACTTTCT
CCTCGAGAAGCGCTGGTACGACGCGATGGCAGAGAAGCCATGCTGCCCGTAGAACAAATTTTAGTGGGCGATATAATTAT
CGTCAAGCCTGGAGAACGCATAGCGATGGACGGCACGGTTATCAAGGGCAACTCCCAGGTAAACCAGGCCCCTATTACCG
GCGAATCACTGCCTGTAGAAAAATCCCCCGGGGCAGATGTGTTTGCTGGTACCATCAATGAAGAGGGATCTCTGGAAGTA
ACAGTTACCAGGCTGGCGCAGGATACTACGCTGGCTAAAATTATTGACCTGGTGGAGGAAGCCCAGGCTCAGCGGGCACC
CTCCCAGCAGTTTGTGGACGTATTCGCCAAGTACTACACTCCGGTAGTAATCGCCGTGGCGCTAGCCATTGCCACGGTCC
CCACCCTTGCTCTGGGGCAGCCCTTTATCCCCTGGCTGGAAAAGGCACTGATTCTGCTGGTGATCGCCTGTCCCTGCGCG
CTGGTGATATCCACCCCGGTGGCCATTGTATCGGCCATCGGCAGCGCTGCCCGGCGTGGAGTACTGATAAAAGGCGGAGC
CTACCTGGAAAAGGCGGGTGCTTTAACGGCGGTGGCCTTTGATAAAACCGGCACCCTCACCAGGGGACGCCCTGAAGTTA
CTGATGTAGTAGTTATGCCCGGCTTTCAAAAGCAGTTTCTGCTGGATATAGCCGCGGCGGTAGAAGGCCGTTCCCAGCAT
CCGGTGGCTCGGGCCATTCTCCGTTATACCGAAAGCCATGAAGCGGCAGTACCCCCCGGCGAACAATTCCAATCTTTTAC
CGGCCAGGGGGCCATGGCCGTAGTTGATGGTAAAGACTATTATATAGGAAACGAAAGATTATTCCAAAGATTGGGTACCG
ACCTGACCGGGGTGCAACAACAGCTGGATGTACTGCAAAGTCAGGGCAAAACAGCCATGCTGGTAGGCACAGCGGATCAG
CCAATGGGCATTATCGCCGTAGCTGATCGGGTGCGTTCCAATAGCGCGGCTGCTCTGCAGGGATTGCGCTCAGCCGGTAT
AAAAAGGCTGGTGATGCTCACCGGGGATAATACCGCCACCGCCGGCGCTATTGCCGATCACCTGGGTGGTCTGGAATATA
AAGCGGAATTGCTGCCCCAAGATAAACTGTCCACCATCAAGGAACTGCAGTCACGTTACGGCAAGGTGGCTATGGTGGGG
GACGGGGTCAACGACACACCGGCGCTGGCTGCTGCCGACATTGGCATCGCCATGGGCGGCGCGGGTACCGACACTGCATT
GGAGACAGCAGATATTGCTTTAATGGCTGACGACCTGGGCAAGCTGCCCTATACCATAAAACTGGGCCGACGGACACTGG
GGATAATTAAACAGAATATCACCTTTGCCCTGCTGGTAAAAGCACTGTTTATTGTGGGTACATTTTTGGGATTCACCAAC
CTCTGGATGGCGGTTTTCGCCGATACTGGCGCTGCCATGATTGTAATAGCCAACGGCATGCGCCTGATGCGGGTGCAGGA
GGACCGGCTGACAGCATAG

Protein sequence :
MTQCSGHNCSCVKNNIMEELTSEGLQQPMKVTKPEEKAINNSAPHLNGMQKSVFVLHGLDCADCAAKLEKRIAGLSGVEE
ATINFGASKMSVRHTTGVPQILRAIKEAGYAAESDHAAATQTNQPLWHDPKLILTVISGLFLAGGMTASLFNLGDRLVID
LLLAAMLSGGYFVVKNDLYSIKALSLDMNVLMSVAAIGAVAIGEWFEGATVVFLFSLGNTLQAYSMAKTRSSIRALMELS
PREALVRRDGREAMLPVEQILVGDIIIVKPGERIAMDGTVIKGNSQVNQAPITGESLPVEKSPGADVFAGTINEEGSLEV
TVTRLAQDTTLAKIIDLVEEAQAQRAPSQQFVDVFAKYYTPVVIAVALAIATVPTLALGQPFIPWLEKALILLVIACPCA
LVISTPVAIVSAIGSAARRGVLIKGGAYLEKAGALTAVAFDKTGTLTRGRPEVTDVVVMPGFQKQFLLDIAAAVEGRSQH
PVARAILRYTESHEAAVPPGEQFQSFTGQGAMAVVDGKDYYIGNERLFQRLGTDLTGVQQQLDVLQSQGKTAMLVGTADQ
PMGIIAVADRVRSNSAAALQGLRSAGIKRLVMLTGDNTATAGAIADHLGGLEYKAELLPQDKLSTIKELQSRYGKVAMVG
DGVNDTPALAAADIGIAMGGAGTDTALETADIALMADDLGKLPYTIKLGRRTLGIIKQNITFALLVKALFIVGTFLGFTN
LWMAVFADTGAAMIVIANGMRLMRVQEDRLTA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 3e-146 48
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 3e-146 48
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 3e-146 48
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 2e-121 46

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Desgi_2314 YP_007945409.1 copper/silver-translocating P-type ATPase,heavy metal-translocating P-type ATPase, Cd/Co/Hg/Pb/Zn-transporting BAC0298 Protein 3e-119 46
Desgi_2314 YP_007945409.1 copper/silver-translocating P-type ATPase,heavy metal-translocating P-type ATPase, Cd/Co/Hg/Pb/Zn-transporting BAC0092 Protein 7e-89 43
Desgi_2314 YP_007945409.1 copper/silver-translocating P-type ATPase,heavy metal-translocating P-type ATPase, Cd/Co/Hg/Pb/Zn-transporting BAC0124 Protein 2e-91 41
Desgi_2314 YP_007945409.1 copper/silver-translocating P-type ATPase,heavy metal-translocating P-type ATPase, Cd/Co/Hg/Pb/Zn-transporting BAC0100 Protein 7e-71 41