Gene Information

Name : Desgi_2227 (Desgi_2227)
Accession : YP_007945332.1
Strain : Desulfotomaculum gibsoniae DSM 7213
Genome accession: NC_021184
Putative virulence/resistance : Virulence
Product : flagellar protein export ATPase FliI
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2265971 - 2267287 bp
Length : 1317 bp
Strand : -
Note : PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: ATPase FliI/YscN family; flagellar protein export ATPase FliI

DNA sequence :
ATGCAGGAACTGGTAAATGAAATCAGGCATTGGCGGCGAAAAGTAAGCCAGGCCAAACTATTGCGGTCCACGGGAAAGGT
AACCAAAGTAATTGGCCTTACGGTTGAAGCAAAAGGAATTACTGCGGGCATTGGACAAGTTTGTGATATTTATATTCCCG
GTGAACGCAATCCGGTTATGGCGGAAGTGGTAGGCTTTCAGGAAGATTCTTCAATATTAATGCCCCTTGGAGAACTGCGC
GGCATTTACCCGGGCTGTACGGTAGTGCCCCGAAGTGAAGCATTAATTATAGGAGTGGGCGAAGGTCTTTTGGGCCGGGT
ACTGGACGGGTTGGGTAGACCTATAGATGGTAAAGACCTTACCCTGCGGGGCACATATTCTGTAAACAATCCCCCGCCGG
ACCCGCTGCAAAGAAAGCGTATCAATAAAATTTTTACCACCGGGGTTCGGGCTATAGATGCGTTAATGACCTGTGGTCAG
GGACAGCGTATTGGTATTTTTGCCGGCAGTGGGGTAGGTAAAAGTACAATTTTGGGCATGATGGCCCGGTTTTGCAATGC
CGACCTAAATGTAATTGCTCTAATCGGCGAGCGTGGCCGCGAGGTCCGCGAATTTATAGAAAATGACCTTGGGCCCGATG
GTATGAAACGTTCCATAGTAGTAACCGCTACCTCGGATCAACCGGCTTTAGTCAGACTGAAGGGCGCTTTTGTAGCCAGT
GCCATTGCGGAATATTTTAGAGATCAGGGTAAAAATGTATTACTTTTTATGGATTCTATAACCCGTTTTGCTATGGCCCA
ACGTGAGGTTGGGTTGGCCGTGGGGGAGCCGCCGGCAACCAAAGGTTACACCCCATCTGTCTTTAGCCTGCTGCCAAAGC
TGTTGGAACGCTCAGGTAGTTCGAAAAATGGTACTATCACCGCTTTTTATACCGTTCTTGTGGAAGCGGACGATATGAAT
GAACCCATAGCCGATGCAGTTAGGGGCATATTGGACGGGCATATTGTATTATCACGTGAATTAGCGGCACGGGGCCATTA
CCCGGCTATTGATGTATTAAACAGCGTGAGCAGGCTGGCGACGAATTTGGTTGATAAAAACCATGCCCTGGCAGCTGCCC
GGTTGAGGCATCTTTTGGCAACTTATACACAGTCTGAAGATTTGATTAATATAGGTGCCTATGTAAAAGGGACAAGCCCT
GAAATTGACAATGCAATAAATAAATATGATAAAATTCTAAAATTTTTACTACAAAATAAGGACGAAGAGAGCAGTTTTGA
TCAAACATTACAAGAACTATTAAAGTTTAGGCGGTAG

Protein sequence :
MQELVNEIRHWRRKVSQAKLLRSTGKVTKVIGLTVEAKGITAGIGQVCDIYIPGERNPVMAEVVGFQEDSSILMPLGELR
GIYPGCTVVPRSEALIIGVGEGLLGRVLDGLGRPIDGKDLTLRGTYSVNNPPPDPLQRKRINKIFTTGVRAIDALMTCGQ
GQRIGIFAGSGVGKSTILGMMARFCNADLNVIALIGERGREVREFIENDLGPDGMKRSIVVTATSDQPALVRLKGAFVAS
AIAEYFRDQGKNVLLFMDSITRFAMAQREVGLAVGEPPATKGYTPSVFSLLPKLLERSGSSKNGTITAFYTVLVEADDMN
EPIADAVRGILDGHIVLSRELAARGHYPAIDVLNSVSRLATNLVDKNHALAAARLRHLLATYTQSEDLINIGAYVKGTSP
EIDNAINKYDKILKFLLQNKDEESSFDQTLQELLKFRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-85 53
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 4e-85 53
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 4e-85 53
lscN AAO18044.1 LscN Virulence TTSS locus Protein 1e-93 52
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 4e-85 52
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-83 52
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-83 52
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 1e-83 52
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-83 52
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-84 52
unnamed AAL06369.1 EscN Virulence LEE Protein 2e-76 52
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 8e-77 51
escN YP_003236088.1 translocator EscN Virulence LEE Protein 3e-77 51
escN CAC81862.1 EscN protein Virulence LEE II Protein 5e-77 51
escN AAK26715.1 EscN Virulence LEE Protein 2e-76 51
escN AAL57542.1 EscN Virulence LEE Protein 2e-76 51
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-76 51
escN CAI43874.1 EscN protein Virulence LEE Protein 9e-77 51
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 2e-79 51
ECs4568 NP_312595.1 EscN Virulence LEE Protein 9e-77 50
escN AAC31513.1 L0034 Virulence LEE Protein 7e-77 50
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 7e-77 50
escN NP_290268.1 hypothetical protein Virulence LEE Protein 9e-77 50
escN AAC38383.1 EscN Virulence LEE Protein 8e-77 50
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 4e-74 50
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-74 50
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 3e-75 50
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-75 50
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-75 50
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 8e-65 48
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 2e-65 47
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 1e-69 47
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 1e-69 47
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 4e-68 46
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 3e-77 45
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 4e-72 45
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 4e-72 45
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 3e-72 45
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 7e-71 45
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 2e-62 44
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 2e-62 44
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-60 42
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 3e-60 42
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-60 42
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-60 42
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 2e-60 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Desgi_2227 YP_007945332.1 flagellar protein export ATPase FliI VFG2144 Protein 5e-97 54
Desgi_2227 YP_007945332.1 flagellar protein export ATPase FliI VFG0192 Protein 6e-93 53
Desgi_2227 YP_007945332.1 flagellar protein export ATPase FliI VFG0048 Protein 7e-90 53
Desgi_2227 YP_007945332.1 flagellar protein export ATPase FliI VFG1254 Protein 2e-89 52
Desgi_2227 YP_007945332.1 flagellar protein export ATPase FliI VFG0390 Protein 4e-92 51
Desgi_2227 YP_007945332.1 flagellar protein export ATPase FliI VFG0812 Protein 4e-77 50
Desgi_2227 YP_007945332.1 flagellar protein export ATPase FliI VFG0730 Protein 4e-77 50
Desgi_2227 YP_007945332.1 flagellar protein export ATPase FliI VFG0515 Protein 2e-75 50
Desgi_2227 YP_007945332.1 flagellar protein export ATPase FliI VFG2331 Protein 5e-84 49
Desgi_2227 YP_007945332.1 flagellar protein export ATPase FliI VFG2499 Protein 8e-86 47
Desgi_2227 YP_007945332.1 flagellar protein export ATPase FliI VFG2459 Protein 5e-71 43
Desgi_2227 YP_007945332.1 flagellar protein export ATPase FliI VFG0555 Protein 1e-60 42