Gene Information

Name : LA14_0974 (LA14_0974)
Accession : YP_007937823.1
Strain : Lactobacillus acidophilus La-14
Genome accession: NC_021181
Putative virulence/resistance : Virulence
Product : Pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 933609 - 935378 bp
Length : 1770 bp
Strand : +
Note : -

DNA sequence :
ATGAAGAAAACTAAGATTGTTAGTACTTTAGGACCAGCTTCAAACGATATTGAAACTATTACTGCTTTAGCTAACGCAGG
CGCAAACGTATTCCGTTTCAACTTCTCACACGGTGACCATGAAGAACACCGTTCACGTATGAACATGGTTCGTGAAGTGG
AAAAGAATACTGGTAAGCTTCTTGGTATTGCTCTTGATACTAAGGGTGCTGAAATCAGAACCACTGAACAAGAAGGTGGC
AAGTTTACTATCAATACTGGTGACACAATCCGTATCTCAATGGACGATACTAAGAAGGGTAACAAGGACATGATCCACGT
TACCTACGACGGCTTGTACGATGATACTCACGTTGGTGGTCACGTATTAATCGATGATGGTTTGGTTGACCTTTTGATCA
AGGAAAAGGACGACGCTAAGAGAGAATTAGTTTGTGAAGCTCAAAACACTGGTTTAATCGGTTCAAAGAAGGGTGTTAAC
GCTCCAGGTGTTGAAATTCGCCTCCCAGGTATCACTCAAAAAGATACTGATGACATTAACTTTGGTTTGAAGGAAGGTAT
CAACTTTATCTTTGCTTCATTCGCACGTAAGGCTCAAGATATCTTAGACATCCGTAAGCTTTGTGAAGCAGCAGGTGCTG
ACTACGTAAAGATTTTCCCTAAGATCGAATCACAAGAAGGTATCGACAACGCTGACGAAATTTTACAAGTTTCTGATGGT
TTGATGGTTGCTCGTGGTGACATGGGTGTTGAAATTCCATTTATGGAAGTTCCATTTGTACAAAAGAACTTAATCAGAAA
AGCTAACGCACTTGGTAAGCCAGTTATTACTGCTACTCAAATGCTTGACTCAATGCAAGAAAACCCACGTCCAACTCGTG
CTGAAGTTTCTGACGTTGCTAACGCTGTTCTTGACGGTACTGATGCAACTATGCTTTCAGGTGAATCAGCAAACGGTTTG
TACCCAGTTAACGCTGTTAAAGCTATGGCTGAAATCGATGAACGTACTGAAAAGCAAATGCTTAAGCGTAACACTTTAGC
ACTTCAAAGATTTGAAGCATACAAGGGCTCAAACGTAACTGAAGCTATCGGTGAATCAGTTGTACGTACTGCACAAGAAT
TAGGTGTTAAGACTATCATCGCTGCAACTAACTCAGGTTACACTGCTCGTATGATTTCTAAGTACCGTCCAAATGCTGAC
ATCGTTGCAATGACCTTCGATGAAAAGATCCAACACTCATTGGCAGTTGTTTGGGGTGTACAACCAGTATTAACTGACAA
GCCTAAGTCAACTGATGACATGTTTGAAAAGGCAGCAGAAGTTGCTAAGGAAAAGGGCTACGTTAAGGATGGTGACCTTG
TAATTATCGTTGCTGGTGTTCCAGTTGGTGATTCAGGTACTACTAACTTGATGAAGTTACAAATTATCGGTAACAAGCTT
GTTCAAGGTTTAGGTGTTGGTAACGGTTCAGTTATCGGCAAGGCTGTTGTTGCAAACTCAGCAGAAGAAGCTAACAGCAA
GGTTAAGGAAGGCGACATCTTAGTTGCTAAGACTACTGATCCAGACTACAACCCAGCTATCAAGAAGGCTTCAGGTTTGG
TTGTTGAAGCTTCAGGTTTAACTTCACACGCAGCAGTTATTGGTTTATCATTAGGTATCCCAGTTGTTGTTGGTGCTACT
GACGCTACTGAAAAGATTTCTGACGGTTCAACTATTACTGTTGATGCTCGTCGTGGTGCTATTTACCAAGGTGAAATCTC
AAACCTTTAA

Protein sequence :
MKKTKIVSTLGPASNDIETITALANAGANVFRFNFSHGDHEEHRSRMNMVREVEKNTGKLLGIALDTKGAEIRTTEQEGG
KFTINTGDTIRISMDDTKKGNKDMIHVTYDGLYDDTHVGGHVLIDDGLVDLLIKEKDDAKRELVCEAQNTGLIGSKKGVN
APGVEIRLPGITQKDTDDINFGLKEGINFIFASFARKAQDILDIRKLCEAAGADYVKIFPKIESQEGIDNADEILQVSDG
LMVARGDMGVEIPFMEVPFVQKNLIRKANALGKPVITATQMLDSMQENPRPTRAEVSDVANAVLDGTDATMLSGESANGL
YPVNAVKAMAEIDERTEKQMLKRNTLALQRFEAYKGSNVTEAIGESVVRTAQELGVKTIIAATNSGYTARMISKYRPNAD
IVAMTFDEKIQHSLAVVWGVQPVLTDKPKSTDDMFEKAAEVAKEKGYVKDGDLVIIVAGVPVGDSGTTNLMKLQIIGNKL
VQGLGVGNGSVIGKAVVANSAEEANSKVKEGDILVAKTTDPDYNPAIKKASGLVVEASGLTSHAAVIGLSLGIPVVVGAT
DATEKISDGSTITVDARRGAIYQGEISNL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-79 47
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 8e-80 47
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 8e-80 47
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-79 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
LA14_0974 YP_007937823.1 Pyruvate kinase VFG0479 Protein 3e-80 47