Gene Information

Name : LA14_0667 (LA14_0667)
Accession : YP_007937520.1
Strain : Lactobacillus acidophilus La-14
Genome accession: NC_021181
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit ClpA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 623866 - 626052 bp
Length : 2187 bp
Strand : -
Note : -

DNA sequence :
TTGCTTTGCCAAAATTGTCATCAACGGCCTGCCGCTATTCACCTTTTTACAAAGGTAAATGGTCAAAGCCGTGAAATTGA
TTTATGTCAACAATGTTATCAAGAATTAAGAAATCAACAAGGAAATCTAGAAAATATGAACAACAATAACGAATTTTTTG
GCGACTTTGATGATTTATTTAACGCATTAAACGGAAATAACAACAACGCCGCAAATAACAATAATAATATGAAAAATAAC
GACCCAAGAATGCAAATGGGTGGTGGAAATGGTGGTCAAGGTGGTAGAAGCTTACTTGATCAATATGGTACTGATTTAAC
TGCTCTTGCTAAAAAAGGTAAAATCGATCCAGTTATCGGTCGTGATAAAGAAATCGCTCGCGTAATTGAAATTTTAAACA
GAAGGACTAAGAATAATCCAGTTTTAATTGGTGAAGCCGGTGTTGGTAAGACAGCTGTAGTTGAAGGCCTTGCTCAAGAA
ATTGTAGATGGTTCTGTTCCAGCTAAACTTCAGAATAAACGTATTATTTCATTAAATGTTGTATCACTTGTTCAAGGTAC
TGGCATTCGTGGTCAATTTGAACAAAGAATGGAACAATTGATTAGAGAATTACAACAAAATGATGATATCATCCTCTTTA
TTGATGAAATTCATGAAATTGTAGGCGCCGGAAATGCCGAAGGCGGTATGGACGCAGGTAATATTATCAAACCTGCTTTA
GCTCGTGGTGAACTCCAATTAGTTGGTGCTACTACTATTAAAGAATATCGTGATATTGAAAAAGATTCAGCTTTAGCACG
TAGATTCCAACCAGTTGAAGTAAAAGAGCCTTCAATTGATGAAACGATTCGCATTTTGAAGGGAATCCAACAACGTTATG
AAGACTATCATCATGTTCAATACTCCGATGATTCCATTGAGTCTGCTGTTAAATTATCAGCTAGATACATTCAAGATAGA
TTCTTACCTGACAAGGCTATTGATCTTTTAGATGAAGCCGGTTCAAGAATGAATTTAACTATTCCTTATATTGATAAAGG
AAAAATGCAAGAACGTATTAACGCTGCAGAACAATTAAAAGAGGAATCTTTAAAGAACGAAGACTACGAAAAAGCAGCTT
ATTATCGTGATCAAATCGAAAAATATGAAAAGATGAAGGATCAAAAAGTTGATCCTGATAAATCACCAATTATTACCGAT
AAGATTATGAACAAGATTGTCGAAGAAAAGACAGGAATTCCTGTTGGTGATATTCAAAAGCAAGAAGAAAATCAATTGCA
AAACTTGGCTAGTGATTTAAAGTCTAATGTTATTGGTCAAGACAAGGCAGTCGAAAAAGTTGCTCGAGCTATTCGACGTA
ACAGAATCGGTTTCAATAAGTCAGGACGTCCAATTGGTTCCTTCCTATTTGTTGGGCCAACCGGTGTTGGTAAGACCGAA
TTAGCTAAACAACTAGCCAAGCAAATGTTTGGTTCAGAAGATGCCATGATTCGTTTCGATATGTCAGAATACATGGAACA
ATATTCTGTCTCCAAATTAATCGGCTCTGCTCCAGGTTACGTAGGTTATGAAGAAGCTGGTCAATTAACTGAACAAGTTC
GCCATAATCCATATAGCTTGATTCTACTTGATGAAATTGAAAAAGCTCATCCAGATGTTTTGAATCTTTTCTTACAAATC
TTAGACGACGGCCGCTTAACTGACTCTCAAGGTAGAACCGTTTCATTTAAGGATACTATTATTATTATGACTTCTAACGC
AGGCCAAGGTATCAAGAATGCCAGCGTTGGTTTTACTGCTGAAAATGATGACGAATCTAGCGAATCAGCAAGAAATAATA
TGAGTCAATTCTTTAAACCAGAATTTTTAAATCGTCTAGATGATGTAATTGAATTCAATGAATTGACTAAGCCAGACTTA
TTGGAAATTGTAGATCTTATGCTTCAAAACACTAACAATATGGTTAAGGATCAAGGCTTACATATTGACGTAACCTCAGC
TGCTAAAAATAAGCTTGTTGAAGAAGGCTTTAATCCTGCTTTAGGTGCCCGTCCTCTTCGTCGTACAATTCAAGAAGAAA
TTGAAGATAAAGTTGCAGATTACAAGCTTGACCATACTGAAAGTAAAAACTTAAAGGCTGACGTAATTAATGATCAAATC
GTAATCAGTGACGAAACAGCTCAATAA

Protein sequence :
MLCQNCHQRPAAIHLFTKVNGQSREIDLCQQCYQELRNQQGNLENMNNNNEFFGDFDDLFNALNGNNNNAANNNNNMKNN
DPRMQMGGGNGGQGGRSLLDQYGTDLTALAKKGKIDPVIGRDKEIARVIEILNRRTKNNPVLIGEAGVGKTAVVEGLAQE
IVDGSVPAKLQNKRIISLNVVSLVQGTGIRGQFEQRMEQLIRELQQNDDIILFIDEIHEIVGAGNAEGGMDAGNIIKPAL
ARGELQLVGATTIKEYRDIEKDSALARRFQPVEVKEPSIDETIRILKGIQQRYEDYHHVQYSDDSIESAVKLSARYIQDR
FLPDKAIDLLDEAGSRMNLTIPYIDKGKMQERINAAEQLKEESLKNEDYEKAAYYRDQIEKYEKMKDQKVDPDKSPIITD
KIMNKIVEEKTGIPVGDIQKQEENQLQNLASDLKSNVIGQDKAVEKVARAIRRNRIGFNKSGRPIGSFLFVGPTGVGKTE
LAKQLAKQMFGSEDAMIRFDMSEYMEQYSVSKLIGSAPGYVGYEEAGQLTEQVRHNPYSLILLDEIEKAHPDVLNLFLQI
LDDGRLTDSQGRTVSFKDTIIIMTSNAGQGIKNASVGFTAENDDESSESARNNMSQFFKPEFLNRLDDVIEFNELTKPDL
LEIVDLMLQNTNNMVKDQGLHIDVTSAAKNKLVEEGFNPALGARPLRRTIQEEIEDKVADYKLDHTESKNLKADVINDQI
VISDETAQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 9e-153 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
LA14_0667 YP_007937520.1 ATP-dependent Clp protease ATP-binding subunit ClpA VFG0080 Protein 0.0 61
LA14_0667 YP_007937520.1 ATP-dependent Clp protease ATP-binding subunit ClpA VFG0079 Protein 6e-158 51