Gene Information

Name : LA14_0279 (LA14_0279)
Accession : YP_007937182.1
Strain : Lactobacillus acidophilus La-14
Genome accession: NC_021181
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit ClpA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 276365 - 278842 bp
Length : 2478 bp
Strand : +
Note : -

DNA sequence :
ATGGAAAACTCATACAGTAAAAGTGTAAATCAAGTGTTGGAAATTGCGCGTGAACAAGCACAGAATTTCCATCATCGTTT
AATCGGAACAGAACATATTTTATTAGCCTTAGTAATTGAAACTGATGGCGAAGCTGGAAAAATTTTACGTTCATGGGGGC
TGACGCCTACCGCTATACGTGAAGAAATTGAAAGATATACAGGATATGGCTCAGCTCCCAAGGCTAGCTATATGGAAATG
TCACCTCGATTGAGCTTGGCTTTAGATTATGCTAAAAGACAAGCAGAACAAGGTGGATATAAAGAAATTAAAACCAATCA
TGTGTTATTAGGTATAACTGCTAGTGAGCAAGTTTTATCTGCAATGATTTTGAAAAACTTAAGCGTAGATATCAGTCGAT
TACGTCAAGATGCTATCGACAGCTTGGAACAGGATCAAGATTTTAATGATTCTGCTAATTGGTTAGGTAATAGTGATTCT
AACCAAAAGAAACGTAAGAATAGCACTACGCCAACCTTGGATAAAGTAGCAATTAACTTGAATCAACGTACACGTGAAGG
AAATATTGATCCTGTTATTGGACGTGATAAGGAAATTGAACGTGTAATTCAAATTTTGTCACGTAGAACTAAGAATAATC
CGGTTTTAGTAGGTGAGCCAGGTGTAGGTAAGACGGCTGTTGCTGAAGCAATTGCTACTGAAATTGTTAAAAAGAGAGTG
CCAGAAGATCTGTTAGATAAGCGAGTTATGGCATTAAATATGGGTAACTTGGTTGCTGGTACTAAATATCGTGGTGAATT
CGAAGATCGAATGAAGAAGATCTTGGATGAAATTGCTAAAGATGGCAAAGTTATCTTATTTGTTGATGAAATGCATACTT
TAATTGGTGCCGGTGGTGCTGAAGGCGCAATTGATGCTTCTAATATTTTAAAGCCATCACTTGCTCGTGGTGATGTTCAA
ATGATTGGTGCTACTACATTTGATGAATACCAAAAATACATTGAAAAAGATCAAGCTTTGGCAAGACGTTTCCAACAAGT
GCGCTTAAATGAACCTTCAAAGAAAGATACATTAGCAATTTTGGAAGGTTTAAAACCCAAGTATGAAAAATTCCATCATG
TTACTATTACTGAAGAAAGTCTAGAAGACGCAGTTGATTTATCTAGTCGATATATTTCTGATCGCTTTTTACCAGATAAA
GCCATTGACTTGGTAGACGAAGCTAGTGCTGCTGTAAAAATCAAAAATAATGTTAATTCTGATGACGAATTAGTACAGAT
TAATAACAAGATTAAAAATTTAATTGATCAAAAAAATGAAGCAGCAGCAAGTCAAAACTTCGTAAAAGCTGCTCAATTAC
AAGATGAGCAAAATAATTTGCAAGCTCGTCGTGAAAAATTAGTAAATACTTTACATGAAAAAATTAGTGCTAATGCGACT
GTTGAGCCCGAAGATATTGCCAAAGTAGTATCTGATTGGACTGGCGTTCCTGTTACCCAAATGAAACGTAATGAAACTCG
TCAATTAGCTAATTTAGAAGGTATTTTACATAAGCGAGTTATTGGTCAAGATAAGGCTGTTTCTGCAGTTGCTCGTGCAA
TCCGTAGAAGTAGAAGCGGAATTAAGGATGAACGTCGTCCAATTGGCTCATTCTTGTTCTTAGGCCCAACTGGTGTGGGT
AAAACAGAATTGGCTAAATCTGTTGCTGCAGCAATGTTTGGCTCAGAGGATAACCTGATACGGCTTGATATGTCTGAATA
CATGGATCAAATCGCTTCAAGTAAATTGATCGGTTCAGCACCAGGCTATGTAGGTTATGAAGAAGGCGGTCAACTTTCAG
AACAAGTTCGTCGCCATCCATATTCAGTTGTGTTGCTCGATGAAGTAGAAAAAGCTCATCCTGATGTATTTAATCTCTTA
CTTCAGGTCTTGGATGAAGGATTTATGACTGATTCTAAGGGAAGGAAAGTTGATTTTAGAAATACAATCATTATTATGAC
TTCTAACCTTGGTTCACGTTCATTATTTGATGGCAATGCGGTTGGATTCAATGCGGATAAAATTGATCAAGCAAAAGTAA
GACAAGCGAAAGTTCAACAAGCTATTAAACAGTTCTTCCGCCCTGAATTTTTAAACAGAATTGATGAAACTATTGTCTTT
GATGAATTAACTAAGAAACAACTTCGTAACATTGTAAGTTTACTTACTAATAAATTGGTAGTTCGTTTACAAAGAAAAGG
TATTACTTTGAAACTTTCACGTGCTGCTTTAGATAAGATCGTACAAGATGGTTATGATCCAGAAAATGGTGCTCGTCCAC
TTAAGAGAGCTATTCAAAATGATGTGGAAGATAAAGTTGCCGAAATGTTAATTAATGGGGAAGTTAAGAGTGGTGATACT
CTTAAAATTGGTAGTCAACATGGTAATTTGAAATTCGAAGTTGTTGCACCTAAAAAAGAAGTAGAAAAAGTCAAGTAG

Protein sequence :
MENSYSKSVNQVLEIAREQAQNFHHRLIGTEHILLALVIETDGEAGKILRSWGLTPTAIREEIERYTGYGSAPKASYMEM
SPRLSLALDYAKRQAEQGGYKEIKTNHVLLGITASEQVLSAMILKNLSVDISRLRQDAIDSLEQDQDFNDSANWLGNSDS
NQKKRKNSTTPTLDKVAINLNQRTREGNIDPVIGRDKEIERVIQILSRRTKNNPVLVGEPGVGKTAVAEAIATEIVKKRV
PEDLLDKRVMALNMGNLVAGTKYRGEFEDRMKKILDEIAKDGKVILFVDEMHTLIGAGGAEGAIDASNILKPSLARGDVQ
MIGATTFDEYQKYIEKDQALARRFQQVRLNEPSKKDTLAILEGLKPKYEKFHHVTITEESLEDAVDLSSRYISDRFLPDK
AIDLVDEASAAVKIKNNVNSDDELVQINNKIKNLIDQKNEAAASQNFVKAAQLQDEQNNLQARREKLVNTLHEKISANAT
VEPEDIAKVVSDWTGVPVTQMKRNETRQLANLEGILHKRVIGQDKAVSAVARAIRRSRSGIKDERRPIGSFLFLGPTGVG
KTELAKSVAAAMFGSEDNLIRLDMSEYMDQIASSKLIGSAPGYVGYEEGGQLSEQVRRHPYSVVLLDEVEKAHPDVFNLL
LQVLDEGFMTDSKGRKVDFRNTIIIMTSNLGSRSLFDGNAVGFNADKIDQAKVRQAKVQQAIKQFFRPEFLNRIDETIVF
DELTKKQLRNIVSLLTNKLVVRLQRKGITLKLSRAALDKIVQDGYDPENGARPLKRAIQNDVEDKVAEMLINGEVKSGDT
LKIGSQHGNLKFEVVAPKKEVEKVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 3e-168 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
LA14_0279 YP_007937182.1 ATP-dependent Clp protease ATP-binding subunit ClpA VFG0079 Protein 0.0 52
LA14_0279 YP_007937182.1 ATP-dependent Clp protease ATP-binding subunit ClpA VFG0080 Protein 6e-143 49