Gene Information

Name : SFUL_98 (SFUL_98)
Accession : YP_007928968.1
Strain : Streptomyces fulvissimus DSM 40593
Genome accession: NC_021177
Putative virulence/resistance : Virulence
Product : Aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : 1.2.1.3
Position : 96325 - 97848 bp
Length : 1524 bp
Strand : +
Note : gene_name:thcA; pathway_coverage:01.20.28.10 degradation of putrescine to 4-aminobutanoate; pathway_coverage:01.01.89.22 degradation of histidine to aspartate via imidazolepyruvate and imidazoleacetaldehyde (bacteria); pathway_coverage:01.05.03.01 D-glucu

DNA sequence :
ATGACCCGTTACGCTGCGCCGGGCACTGAGGGCGCGATCGTCACGTACGCGTCCCGCTACGACCACTGGATCGGCGGCGC
GTACGTCCCGCCGGTCCGGGGCCAGTACTTCGAGAACCCGAGCCCCGTCAACGGCCGCCCCTTCACCGAGATCGCCCGTG
GCACCGCCGAGGACGTCGAACTGGCCCTGGACGCGGCGCACTCGGCCGCACCCGCGTGGGGAGCGACCTCCGCGGGCGAC
CGGGCGGCCGTCCTGAACCGGGTCGCGGACCGTATGGAGGCGCATCTTGAGGAGCTGGCGGTCGCCGAGAGCTGGGACAA
CGGAAAGCCGGTGCGCGAGACGATGGCCGCCGACATCCCGCTGGCCATCGACCACTTCCGCTACTTCGCGGGGGTCCTCC
GGGCCCAGGAGGGCTCGCTCAGCGAGCTGGACGAGGACACCGTCGCGTACCACTTCCACGAGCCCCTGGGCGTGGTCGGC
CAGATCATCCCGTGGAACTTCCCGATCCTGATGGCCACCTGGAAGCTCGCCCCGGCGCTGGCCGCGGGCAACGCGGTGGT
GCTCAAGCCGGCCGAGCAGACTCCGGCGTCGATCCACTTCTGGATGAGTCTGGTGGCCGATCTGCTGCCGCCGGGCGTCA
TCAACATCGTCAACGGCTTCGGCGAGGAGGCCGGAAAGCCGCTGGCCTCCAGCCCGCGCGTCGCGAAGATCGCGTTCACC
GGTGAGACCACGACAGGGCGGCTGATCATGCAGTACGCCTCCGAGAACCTCAAGCCGGTCACGCTGGAGCTCGGCGGCAA
GTCGCCGAACATCTTCTTCGACGACGTCTCCCGCAGCGACGACGACTTCCTCGACAAGGCCCTCGAAGGGTTCACGATGT
TCGCCCTCAACCAGGGTGAGGTGTGTACGTGTCCCTCGCGCGCCTTCATCCAGCGCGGGCACTACGGTGCGTTCCTGGAG
GCCGGGGTCGCCCGCACCGAGAAGATCGTGCCGGGCAACCCCCTGGACACCGACACGATGATCGGTGCGCAGGCGTCCGA
CGCCCAGCTCCAGAAGATCCTCTCCTACCTGGAGATCGGCCAGCAGGAGGGCGCGAAGATTCTCACGGGCGGTCAGCGCA
TCGAGCACGGCGGCGAACTGGCGGGCGGCTACTACGTGCAGCCGACGGTCTTCGAGGGCGACAACCGGATGCGGGTCTTC
CAGGAGGAGATCTTCGGCCCGGTCGTGGCGGTGGCCTCCTTCACCGACTTCGACGACGCCATCACGACGGCCAACGACAC
CCTGTACGGGCTCGGGGCCGGCGTGTGGACCCGCGACACCAACACGGCCTACCGGGCGGGGCGCGCCATCAAGGCGGGCC
GGGTCTGGACGAACTGCTACCACGCCTATCCCGCGCACGCGGCGTTCGGAGGCTACAAGGAGTCGGGCATCGGCCGGGAG
AACCACAAGATGATGCTGGAGCACTACCAGCAGACGAAGAACCTTCTGGTGTCCTACTCGCCGAAGAAGCTGGGCTTCTT
CTAG

Protein sequence :
MTRYAAPGTEGAIVTYASRYDHWIGGAYVPPVRGQYFENPSPVNGRPFTEIARGTAEDVELALDAAHSAAPAWGATSAGD
RAAVLNRVADRMEAHLEELAVAESWDNGKPVRETMAADIPLAIDHFRYFAGVLRAQEGSLSELDEDTVAYHFHEPLGVVG
QIIPWNFPILMATWKLAPALAAGNAVVLKPAEQTPASIHFWMSLVADLLPPGVINIVNGFGEEAGKPLASSPRVAKIAFT
GETTTGRLIMQYASENLKPVTLELGGKSPNIFFDDVSRSDDDFLDKALEGFTMFALNQGEVCTCPSRAFIQRGHYGAFLE
AGVARTEKIVPGNPLDTDTMIGAQASDAQLQKILSYLEIGQQEGAKILTGGQRIEHGGELAGGYYVQPTVFEGDNRMRVF
QEEIFGPVVAVASFTDFDDAITTANDTLYGLGAGVWTRDTNTAYRAGRAIKAGRVWTNCYHAYPAHAAFGGYKESGIGRE
NHKMMLEHYQQTKNLLVSYSPKKLGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-137 60
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 7e-142 59
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 7e-142 59
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 7e-142 59
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-141 59

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SFUL_98 YP_007928968.1 Aldehyde dehydrogenase VFG0082 Protein 9e-138 60