Gene Information

Name : SFUL_786 (SFUL_786)
Accession : YP_007929655.1
Strain : Streptomyces fulvissimus DSM 40593
Genome accession: NC_021177
Putative virulence/resistance : Virulence
Product : Urease subunit alpha
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 919804 - 921525 bp
Length : 1722 bp
Strand : -
Note : ptm:Carbamylation allows a single lysine to coordinate two nickel ions (By similarity); UniProt-pubmed:11572948; subunit:May form a heterohexamer of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits. May also form a heterotrimer of ureA (gamma), ureB (beta

DNA sequence :
ATGCCTGACCTCAGCAGGGCCGTGTACGCGGACCTCTTCGGGCCCACCACCGGCGACCGGATCCGCCTCGCCGACACCGA
CCTCTTCGTCGAGATCGAGGAGGACCGCTCCGGCGGCCCGGGCCACGCGGGCGACGAGGCGGTCTTCGGCGGCGGGAAGG
TGATCCGCGAGTCCATGGGCCAGGCCCGCACCACCCGCGCCGAGGGCGCACCCGACACCGTCATCACCGGCGCGGTCGTG
ATCGACCACTGGGGCATCGTCAAGGCCGACATCGGCATCCGCGACGGCCGGATCACCGGCATCGGCAAGGCCGGGAACCC
GGACACCATGGACGGAGTCCACCCCGACCTGGTGATCGGCCCCGAGACCGAGATCATCGCGGGCAACGGCAAGTTCCTGA
CGGCCGGAGCGGTCGACGCGCACGTCCACTTCATCTCACCGACCCTCGTCGACCAGGCGCTCTCCAGCGGCATCACCACC
CTCGTCGGCGGCGGCACCGGACCCGCCGAAGGCACCAAGGCGACCACCATCACCCCCGGCCCCTGGCACCTTGCCCGGAT
GTTCGAGGCGCTGGAGACCTTCCCCGTCAACATCGGGCTGCTCGGCAAGGGCAACACGACCTCCCGCGACGCCATGTACT
CCCAACTGCGCGGCGGAGCACTGGGGTTCAAGATCCATGAGGACTGGGGTGCCACCCCGGCCGCCATCGACGCCTGCCTC
ACGGTCTGCGAGGAGACCGGCGCCCAGCTCGCCATCCACACCGACACCCTCAACGAGGCCGGGTTCGTCGCCGACACCCT
CGCCGCCATCGCCGGGCGCTCCATCCACGCGTACCACACCGAGGGTGCGGGCGGCGGGCACGCGCCCGACATCATCACCG
TCGTCTCGGAGCCGTACGTCCTGCCGAGCTCGACCAACCCGACCCGGCCGCACACCGTCAACACCATCGAGGAACACCTC
GACATGCTGATGGTCTGCCACCACCTCAACCCCGCCGTCCCCGAGGACCTCGCCTTCGCGGAGTCCCGCATCCGGCCCTC
CACCATCGCGGCCGAGGACATCCTCCACGACCTCGGCGCCATCTCGATCATCTCCTCGGACTCCCAGGCGATGGGCCGCA
TCGGCGAGGTGATCCTGCGGACCTGGCAGACCGCCCACGTCATGAAGAAGCGGCGCGGCGCGCTCGCCGGGGACGGAGCG
GCCGACAACCACCGGGTCCGTCGCTATGTCGCCAAATACACCATCAACCCGGCCGTCGCCCAGGGCCTGGACCGGGAGAT
CGGCTCGGTGGAAAGCGGAAAGCTCGCCGACCTCGTGCTCTGGGACCCGGCGTTCTTCGGGGTGAAGCCGCAGACCGTCA
TCAAGGGCGGCCAGATCGCGTACGCGCAGATGGGCGACGCCAACGCGTCCATCCCGACGCCCCAACCGGTGCTGCCCCGG
CCGATGTTCGGCGCACTGGGCCGGGCCGCCGCACGCGGCTCCTTCAACTTCGTCACGGAGACGGCGATCGAGGACGGACT
GCCCGAACGGCTCGGCCTCGACAAGCGGTTCACCCCGATCACCAGCACCCGGGGGGTCACCAAGGCGGACATGCGGGAGA
ACGACGCGATGCCGCACGTCCAGGTCGACCCAGACAGCTTCGCCGTCACCATCGACGGCGAACCGGTCGAGCCCGCACCG
GCGGCGGAACTGCCCATGGCCCAGCGCTACTTCCTCTTCTGA

Protein sequence :
MPDLSRAVYADLFGPTTGDRIRLADTDLFVEIEEDRSGGPGHAGDEAVFGGGKVIRESMGQARTTRAEGAPDTVITGAVV
IDHWGIVKADIGIRDGRITGIGKAGNPDTMDGVHPDLVIGPETEIIAGNGKFLTAGAVDAHVHFISPTLVDQALSSGITT
LVGGGTGPAEGTKATTITPGPWHLARMFEALETFPVNIGLLGKGNTTSRDAMYSQLRGGALGFKIHEDWGATPAAIDACL
TVCEETGAQLAIHTDTLNEAGFVADTLAAIAGRSIHAYHTEGAGGGHAPDIITVVSEPYVLPSSTNPTRPHTVNTIEEHL
DMLMVCHHLNPAVPEDLAFAESRIRPSTIAAEDILHDLGAISIISSDSQAMGRIGEVILRTWQTAHVMKKRRGALAGDGA
ADNHRVRRYVAKYTINPAVAQGLDREIGSVESGKLADLVLWDPAFFGVKPQTVIKGGQIAYAQMGDANASIPTPQPVLPR
PMFGALGRAAARGSFNFVTETAIEDGLPERLGLDKRFTPITSTRGVTKADMRENDAMPHVQVDPDSFAVTIDGEPVEPAP
AAELPMAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 1e-159 60
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 1e-159 60
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 5e-148 58
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-148 58
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 2e-148 58
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-148 58

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SFUL_786 YP_007929655.1 Urease subunit alpha VFG0270 Protein 3e-138 55