Gene Information

Name : SFUL_6974 (SFUL_6974)
Accession : YP_007935736.1
Strain : Streptomyces fulvissimus DSM 40593
Genome accession: NC_021177
Putative virulence/resistance : Virulence
Product : RNA-directed DNA polymerase (Reverse transcriptase)
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.49
Position : 7844263 - 7845522 bp
Length : 1260 bp
Strand : -
Note : UniProt-pubmed:11932238; UniProt-pubmed:17369815; UniProt-pubmed:21441518; UniProt-pubmed:21304664; UniProt-pubmed:17151343; UniProt-pubmed:19251847; UniProt-pubmed:14528314

DNA sequence :
ATGGATGCGCTGAAAGCGTCAGAGAAGTCGTTCGCTATCTCGAAGTGGGAAGTATGGGAGGCATGGGAGAAGGTTAGGGC
GAACAAGGGTGCGCCGGGGGTGGATGGCTGCACGATTGAGGAGTTCGAGAAGGATCTGAGGGGAAACCTCTACAAGGTCT
GGAATCGAATGTCTTCGGGCAGTTACTTTCCGCCTCCGGTGCGAGCGGTAGAGATTCCGAAGTCGCATGGCGGCGTCAGG
ATTCTTGGTGTTCCCACGGTCGCGGACAGGATTGCGCAAACCGTGGTCGCCGCCCGACTGGAACGGAATGTGGAACCGGT
ATTCCACTCCGATTCTTTCGGGTATCGGCCTGGACGGTCTGCCCTGGACGCGGTGGAGAAATGCCGGGAGAGGACGTGGA
AGAGGGACTGGGTGGTCGATCTGGACATCCAGAAGTTCTTCGACAGCGTCCCCTGGAGCCTCATCGTCAAGGCGGTGGAG
GCTCATGCCGACGCCGTTTGGGTGAAGTTGTATGTGGAACGGTGGCTCCGGGCACCGCTCCAATTGCCCGACGGTACCTT
GCAGAGGCGGGACCGCGGAACCCCTCAAGGTTCGGCGGTCTCGCCTGTGTTGGCGAATCTGTTCCTGCACTACGCGTTCG
ACATGTGGATAGCTCGGGAGTTCCCCGACATCCCGTTCGAGCGGTATGTGGATGACGCGGTCGTGCACTGCGTCAGCGAG
CGTCAGGCCAGGAGACTGGTCGAGGCGATCGGGAACCGTATGGAGGAGGTCGGGCTGCGTCTGCACCCGGCCAAGACCCG
GATCGTCTACTGCAAGGACGCGAACCGGCGGGGTGCATACGCGCAGACGTCGTTCACGTTCCTGGGGTTCACGTTCCGAG
CCCGCGCGGCCCGCAGCAGGCACGGGGTGACCTTCCGGTGCTTTCTGCCGGCGGTCAGCAAGGATGCCTTGAAGAGAATG
AGTGCCGAGGTACGCAGCTGGCGTATTCATCGGCGCACCCGCCATACCTTCGCTCAACTCGCACGGTTCATCAACCCGAT
CGTGCGGGGCTGGATCCAGTATTACGGGGCGTACTACCGCTCCGCGCTGGAGCCCCTCCTGCGGCGCATCAACGCCTATC
TGGTGCGCTGGATCCGCCGAAAGTACAAGCGGCTCGCGGGCTTCAAGAAGGCCAAGGAGTGCTTCCAGGGAATCACACAG
CGATACCCAGGGATGTTCTTCCACTGGCGGTTTGCCCGTCACTTCTGGTGCTCAGGGTGA

Protein sequence :
MDALKASEKSFAISKWEVWEAWEKVRANKGAPGVDGCTIEEFEKDLRGNLYKVWNRMSSGSYFPPPVRAVEIPKSHGGVR
ILGVPTVADRIAQTVVAARLERNVEPVFHSDSFGYRPGRSALDAVEKCRERTWKRDWVVDLDIQKFFDSVPWSLIVKAVE
AHADAVWVKLYVERWLRAPLQLPDGTLQRRDRGTPQGSAVSPVLANLFLHYAFDMWIAREFPDIPFERYVDDAVVHCVSE
RQARRLVEAIGNRMEEVGLRLHPAKTRIVYCKDANRRGAYAQTSFTFLGFTFRARAARSRHGVTFRCFLPAVSKDALKRM
SAEVRSWRIHRRTRHTFAQLARFINPIVRGWIQYYGAYYRSALEPLLRRINAYLVRWIRRKYKRLAGFKKAKECFQGITQ
RYPGMFFHWRFARHFWCSG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed ABR13526.1 reverse transcriptase Not tested PAGI-7 Protein 7e-107 53
unnamed CAD33771.1 putative reverse transcriptase Not tested PAI I 536 Protein 1e-86 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SFUL_6974 YP_007935736.1 RNA-directed DNA polymerase (Reverse transcriptase) VFG1512 Protein 8e-87 46