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Name : SFUL_6402 (SFUL_6402) Accession : YP_007935169.1 Strain : Streptomyces fulvissimus DSM 40593 Genome accession: NC_021177 Putative virulence/resistance : Virulence Product : Sphingomyelinase C Function : - COG functional category : - COG ID : - EC number : 3.1.4.12 Position : 7186378 - 7187367 bp Length : 990 bp Strand : - Note : Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a DNA sequence : GTGCCGCACTCCGCTTTCCGCCGCCTTTCCGGCGTAGCACTCTCCGCCGCCCTCGCCGCCGTCCCGCTGGCTGTGAACAC ACCCCAGGCAGCGGCGGCCGGCACCGCCGACACCCCGTCGCTGCGGGTGCTCTCGTACAACACGTTCATCTTCAGCAAGA CCCTGTACCCCAACTGGGGCCAGGACCACCGGGCGGCGGAGATCCCGAAGACGTCGTTCTTCCGGGGCAACGACGTGGTC GTGATCCAGGAGGCCTTCGACAACGGCGCCTCCGACGCACTGCTGCGGAACTCCGCCGCCCAGTACCCGTACCAGACCCC GGTGGTCGGCCGGAGCAAGAGCGGCTGGGACGCCACCAGCGGCTCGTACTCGGCGACGACCCCGGAGGACGGCGGCGTCA CGATCCTGAGCAAGTGGCCGATCGTCCGCAAGGAGCAGCACGTCTACAAGGACGCCTGCGGCGCCGACTGGTGGTCCAAC AAGGGCTTCGCCTACACCGTGCTGAACGTCAACGGCGCCCGCGTCCACGTCGTCGGTACCCACGCCCAGTCGACCGACCC CGGCTGTTCGGCGGGCGAGGCCGCCCAGATGCGCAGCCGCCAGTTCAAGGCGATGGACGCCTTCCTGGACGCCAAGAAGA TCCCGGCCTCCGAACAGGTCATCGTGGCGGGCGACTTCAACGTGGACGGGCACTCCGCCGAGTACGCCTCCTTCCTCAAG GACGCGGACCTGGCCCCGGCCGACACCAAGACGGGCCACACGTACTCCTTCGACACCCGCGACAACTCGATCGCCTCCGA GCGCTACCCGAACGACCCCCGGGAGGACCTGGACCACGTCCTGCACCGCACGGGCCATGTGAAGCCGTCGGGCTGGAAGA ACGACGTCGTCAAGGAGCAGAGCGCCCCCTGGACGGTCTCCAGCTGGGGCACGAACTACACGTACACGAACCTCTCCGAC CACTACCCGGTGATCGGCTCCGCCAACTGA Protein sequence : MPHSAFRRLSGVALSAALAAVPLAVNTPQAAAAGTADTPSLRVLSYNTFIFSKTLYPNWGQDHRAAEIPKTSFFRGNDVV VIQEAFDNGASDALLRNSAAQYPYQTPVVGRSKSGWDATSGSYSATTPEDGGVTILSKWPIVRKEQHVYKDACGADWWSN KGFAYTVLNVNGARVHVVGTHAQSTDPGCSAGEAAQMRSRQFKAMDAFLDAKKIPASEQVIVAGDFNVDGHSAEYASFLK DADLAPADTKTGHTYSFDTRDNSIASERYPNDPREDLDHVLHRTGHVKPSGWKNDVVKEQSAPWTVSSWGTNYTYTNLSD HYPVIGSAN |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| hlb | NP_646757.1 | truncated beta-hemplysin | Not tested | ¥ÕSa3 | Protein | 5e-56 | 49 |
| hlb | NP_375112.1 | hypothetical protein | Not tested | ¥ÕSa3 | Protein | 2e-56 | 48 |
| truncated-hlb | NP_372527.1 | hypothetical protein | Not tested | ¥ÕSa3 | Protein | 1e-56 | 48 |
| unnamed | CAA70683.2 | sphingomyelinase-c | Virulence | LIPI-2 | Protein | 3e-57 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| SFUL_6402 | YP_007935169.1 | Sphingomyelinase C | VFG1798 | Protein | 2e-60 | 47 |
| SFUL_6402 | YP_007935169.1 | Sphingomyelinase C | VFG0674 | Protein | 2e-57 | 42 |
