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Name : SFUL_4752 (SFUL_4752) Accession : YP_007933533.1 Strain : Streptomyces fulvissimus DSM 40593 Genome accession: NC_021177 Putative virulence/resistance : Resistance Product : Cystathionine gamma-synthase Function : - COG functional category : - COG ID : - EC number : 2.5.1.48 Position : 5251747 - 5252892 bp Length : 1146 bp Strand : + Note : pathway_coverage:01.01.62.12 degradation of methionine to 2-oxobutanoate (cysteine biosynthesis in animals); UniProt-pubmed:11572948; pathway_coverage:01.01.15.15 biosynthesis of cysteine by transsulfuration (animals and microorganisms); cofactor:Pyridoxa DNA sequence : ATGAGCGACCAGCACAGCTTCGAGACTCTCGCGATCCACGCGGGGAACACCGCCGACCCCCTCACCGGCGCGGTGGTTCC GCCCATCTACCAGGTGTCCACGTACAAGCAGGACGGCGTGGGCGGACTGCGCGGCGGCTACGAGTACAGCCGCAGCGCCA ACCCCACCCGTACCGCCCTGGAGGAGAACCTGGCGGCCCTGGAAGGCGGCCGCCGCGGTCTCGCCTTCGCCTCCGGCCTC GCCGCCGAGGACTGCCTCCTGCGTACGCTGCTGACCCCCGGTGACCACGTGGTCATCCCCAACGACGCCTACGGCGGCAC CTTCCGGCTGTTCGCGAAGGTCGCCGCGCGCTGGGGCGTGGAGTTCTCGGTCGCCGACACCTCGGACGTGGCGGCGGTGC GGGCGGCGATCACCCCGCGCACCAAGGCGGTCTGGGTGGAGACCCCCTCCAACCCGCTGCTCAACATCACCGACATCGCC GCCGTCGCCCAGGTCGCGCACCAGGCCGGGGCCCGCCTCGTCGTCGACAACACCTTCGCCTCGCCCTACCTCCAGCAGCC GCTGCCCCTCGGCGCGGACGTCATCGTGCACTCCACCACCAAGTACATGGGCGGCCACTCCGACGTCGTCGGCGGCGCCC TCGTCGTCAGCGACCCGGAGCTTGCCGAGGAGCTGGCGTTCCACCAGAACGCCATGGGCGCGGTCTCCGGCCCCTTCGAC GCCTGGCTCGTGCTGCGCGGCATCAAGACCCTCGCCGTCCGCATGGACCGGCACACCGAGAACGCCACCAAGGTCACCGA GCTGCTGACCCGGCACCCCAAGGTCTCCCAGGTCCTCTACCCGGGCCTGCCCGAGCACCCCGGCCACGAGGTCGCCGCCA AGCAGATGAAGGCCTTCGGCGGCATGGTGTCCTTCCGCGTCAACGGCGGCGAGGAGGCGGCTGTCGAGGTCTGCAACCGG GCGAAGCTCTTCACGCTCGGTGAGTCCCTCGGCGGCGTCGAGTCGCTGATCGAGCACCCCGGCCGGATGACGCACGCCTC CGTCGCGGGCTCCCTGCTGGAGGTCCCCGCCGACCTGGTCCGTCTCTCCGTCGGCATCGAGAACGGCGACGACCTGCTCG CCGACCTCACCCAGGCCCTGGGCTGA Protein sequence : MSDQHSFETLAIHAGNTADPLTGAVVPPIYQVSTYKQDGVGGLRGGYEYSRSANPTRTALEENLAALEGGRRGLAFASGL AAEDCLLRTLLTPGDHVVIPNDAYGGTFRLFAKVAARWGVEFSVADTSDVAAVRAAITPRTKAVWVETPSNPLLNITDIA AVAQVAHQAGARLVVDNTFASPYLQQPLPLGADVIVHSTTKYMGGHSDVVGGALVVSDPELAEELAFHQNAMGAVSGPFD AWLVLRGIKTLAVRMDRHTENATKVTELLTRHPKVSQVLYPGLPEHPGHEVAAKQMKAFGGMVSFRVNGGEEAAVEVCNR AKLFTLGESLGGVESLIEHPGRMTHASVAGSLLEVPADLVRLSVGIENGDDLLADLTQALG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SAR0460 | YP_039909.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 2e-79 | 48 |
| SAS0418 | YP_042545.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 2e-80 | 48 |
| metB | YP_281510.1 | cystathionine beta-lyase | Not tested | Not named | Protein | 9e-61 | 43 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| SFUL_4752 | YP_007933533.1 | Cystathionine gamma-synthase | BAC0207 | Protein | 2e-63 | 45 |
