Gene Information

Name : SFUL_4716 (SFUL_4716)
Accession : YP_007933497.1
Strain : Streptomyces fulvissimus DSM 40593
Genome accession: NC_021177
Putative virulence/resistance : Virulence
Product : Aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : 1.2.1.3
Position : 5216366 - 5217802 bp
Length : 1437 bp
Strand : -
Note : pathway_coverage:01.20.28.10 degradation of putrescine to 4-aminobutanoate; pathway_coverage:01.20.30.02 serotonin degradation; pathway_coverage:01.01.89.16 degradation of histidine to aspartate via histamine; UniProt-pubmed:21463507; pathway_coverage:01.

DNA sequence : 
ATGGCATCTGCATTCGAGTACGCACCGGCGCCGGAGTCCCGCTCCGTCGTCGACATCGCCCCCTCGTACGGGCTGTTCAT
CGACGGTGAGTTCACCGAGGCCGCCGACGGCAAGGTCTTCAAGACCGTCTCGCCGAGCACCGAGGAGGTCCTCTCCGAGG
TCGCGCGGGCGGGCGCGGCGGACGTGGACCGGGCCGTGAAGGCGGCGCGCAAGGCGTTCGAGAAGTGGTCGGCACTGCCC
GGCTCCGAGCGCGCCAAGTACCTGTTCCGGATCGCGCGGATCATCCAGGAGCGCAGCCGTGAGCTGGCCGTCCTGGAGAC
CCTCGACAACGGCAAGCCGATCAAGGAGACCCGCGACGCGGACCTCCCGCTGGTCGCGGCGCACTTCTTCTACTACGCGG
GCTGGGCCGACAAGCTGGACCACGCGGGGTACGGGAGCAACCCCCGGCCGCTGGGTGTGGCGGGCCAGGTTATCCCGTGG
AACTTCCCGCTGCTGATGCTCGCGTGGAAGATCGCCCCGGCGCTCGCCACGGGCAACACGGTGGTCCTGAAGCCCGCCGA
GACGACCCCGCTGAGCGCGCTGTTCTTCGCGGACATCTGCCGCCAGGCCGGGCTGCCGAAGGGTGTCGTCAACATCCTGA
CGGGTTACGGGGACGCGGGCGAGGCCCTCGTCACGCACCCGGACGTCAACAAGGTCGCCTTCACCGGTTCGACCGCCGTC
GGCAAGGCCATCGCGCGCTCCGTCGCGGGCACGGACAAGAAGGTCACGCTGGAGCTGGGCGGCAAGGGCGCCAACATCGT
CTTCGACGACGCCCCGATCGACCAGGCCGTCGAGGGCATCGTCACCGGGATCTTCTTCAACCAGGGCCAGGTCTGCTGCG
CGGGCTCCCGGCTGCTGGTCCAGGAGTCGGTCCAGGACGAGGTGCTGGACGCGCTCAAGCGCCGGCTCTCGACCCTGCGG
CTCGGCGACCCGCTGGACAAGAACACCGACATCGGCGCGATCAACTCCGCCGAGCAGCTCTCCCGGATCACCGCCCTGGT
GGAGACCGGCGAGGCGGAGGGCGCGGAGCGCTGGAGCGCCCCCTGCGACCTGCCGTCGTCGGGTTACTGGTTCGCGCCGA
CCCTCTTCACCAACGTCACCCAGGCCCACACGGTCGCCCGTGACGAGATCTTCGGCCCGGTGCTCTCCGTCCTGACGTTC
CGTACCCCGGACGAGGCGGTGGCCAAGGCCAACAACAGCCAGTACGGCCTCTCCGCCGGCATCTGGACGGAGAAGGGCTC
CCGGATCCTCGCCGTGGCGAACAAGCTCCGCGCGGGCGTCGTCTGGGCCAACACGTTCAACAAGTTCGACCCGACGTCGC
CCTTCGGCGGCTACAAGGAGTCGGGCTACGGCCGCGAGGGCGGCCGCCACGGCCTGGAGGCGTACCTCGATGTCTGA

Protein sequence : 
MASAFEYAPAPESRSVVDIAPSYGLFIDGEFTEAADGKVFKTVSPSTEEVLSEVARAGAADVDRAVKAARKAFEKWSALP
GSERAKYLFRIARIIQERSRELAVLETLDNGKPIKETRDADLPLVAAHFFYYAGWADKLDHAGYGSNPRPLGVAGQVIPW
NFPLLMLAWKIAPALATGNTVVLKPAETTPLSALFFADICRQAGLPKGVVNILTGYGDAGEALVTHPDVNKVAFTGSTAV
GKAIARSVAGTDKKVTLELGGKGANIVFDDAPIDQAVEGIVTGIFFNQGQVCCAGSRLLVQESVQDEVLDALKRRLSTLR
LGDPLDKNTDIGAINSAEQLSRITALVETGEAEGAERWSAPCDLPSSGYWFAPTLFTNVTQAHTVARDEIFGPVLSVLTF
RTPDEAVAKANNSQYGLSAGIWTEKGSRILAVANKLRAGVVWANTFNKFDPTSPFGGYKESGYGREGGRHGLEAYLDV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aldA ACK75580.1 aldehyde dehydrogenase Not tested VPI Protein 4e-50 44
aldA ACK75590.1 aldehyde dehydrogenase Not tested VPI Protein 8e-51 44
aldA ACK75596.1 aldehyde dehydrogenase Not tested VPI Protein 8e-51 44
aldA ACK75577.1 aldehyde dehydrogenase Not tested VPI Protein 4e-51 44
aldA ACK75588.1 aldehyde dehydrogenase Not tested VPI Protein 5e-50 44
aldA ACK75574.1 aldehyde dehydrogenase Not tested VPI Protein 8e-51 44
aldA ACK75585.1 aldehyde dehydrogenase Not tested VPI Protein 2e-50 43
aldA ACK75593.1 aldehyde dehydrogenase Not tested VPI Protein 2e-50 43
aldA ACK75582.1 aldehyde dehydrogenase Not tested VPI Protein 5e-51 43
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 9e-69 43
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 7e-71 43
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-73 42
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-73 42
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-73 42
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-73 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SFUL_4716 YP_007933497.1 Aldehyde dehydrogenase VFG0082 Protein 3e-71 43