Gene Information

Name : SFUL_4589 (SFUL_4589)
Accession : YP_007933370.1
Strain : Streptomyces fulvissimus DSM 40593
Genome accession: NC_021177
Putative virulence/resistance : Unknown
Product : GMP synthase [glutamine-hydrolyzing]
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 5046932 - 5048518 bp
Length : 1587 bp
Strand : +
Note : Catalyzes the synthesis of GMP from XMP (By similarity); UniProt-pubmed:11572948; UniProt-pubmed:20624727; pathway_coverage:01.03.01.04 biosynthesis of GMP from IMP; gene_name:guaA1; UniProt-pubmed:21463507; UniProt-pubmed:21551298; UniProt-pubmed:2105970

DNA sequence :
GTGCCAGCAGCACCCCCCGCCGCCCCCGACACCACGGCCGACGTGGTCCTCGTTGTGGACTTCGGCGCGCAGTACGCCCA
GCTCATCGCCCGCCGTGTCCGTGAGGCCCGGGTCTACAGCGAGATCGTCCCGTCCACCATGCCGGTGGCCGAGATGCTGG
CCAAGAACCCCCGCGCGATCATCCTGTCCGGCGGTCCGTCGTCGGTCTACGCGGAGGGTGCGCCCTCCCTGGACCGCTCG
CTCTTCGAGGCCGGGGTCCCCGTCTTCGGCATGTGCTACGGCTTCCAGCTGATGGCGACGACCCTCGGCGGCACGGTCGA
CGACAACGGGGCCCGTGAGTACGGTCGCACCCCGCTGCACGTCACCAAGGCGGGCTCGACGCTCTTCGAGGGCACGCCCA
CCGAGCAGCCGGTGTGGATGTCGCACGGCGACGCCTGCTCGGCGGCGCCCGAGGGCTTCACCGTCACCGCGTCCACAGAC
GTGGTCCCGGTCGCCGCCTTCGAGAACGACGAGAAGAAGCTCTACGGCGTCCAGTACCACCCGGAGGTCCTGCACTCCAC
CCACGGCCAGCAGGTCCTGGAGCACTTCCTCTACCGCGGTGCGGGCATCGAGCCGAACTGGACCACCACCAATGTGGTCG
AGGAGCAGATCGCCGCGATCCGCGAGCAGGTCGGCGACAAGCGCGCCATCTGCGGCCTCTCCGGCGGCGTGGACTCGGCG
GTCGCGGCGGCGCTCGTCCAGAAGGCCATCGGCTCCCAGCTGACCTGTGTGTACGTCGACCACGGGCTGATGCGCAAGGG
CGAGACCGAGCAGGTCGAGAAGGACTTCGTCGCCGCCACGGGCGCGAAGCTGAAGGTGGTCGACGCGGAGAAGCGCTTCC
TCGACGCCCTGGCCGGGGTCTCCGACCCGGAGCAGAAGCGGAAGATCATCGGCCGCGAGTTCATCCGCGTCTTCGAGCAG
GCCCAGCTGGAGATCCTCCAGGAGGACGGCCCCGAGGTCGCCTTCCTGGTCCAGGGCACGCTCTACCCGGACGTCGTGGA
GTCCGGCGGCGGCACCGGCACCGCCAACATCAAGTCCCACCACAACGTGGGCGGCCTCCCCGACGACATCGAGTTCCAGC
TCGTCGAGCCGCTGCGCCAGCTGTTCAAGGACGAGGTCCGGATGGTCGGCCAGGAGCTCGGCCTGCCGGAGGAGATCGTC
CAGCGCCAGCCGTTCCCCGGCCCCGGCCTCGGCATCCGCATCGTCGGCGAGGTCACCAAGGACCGCCTGGACCTGCTCCG
CGAGGCCGACGCCATCGCCCGCGAGGAGCTGACGGCGGCCGGTCTGGACCGCGACATCTGGCAGTGCCCGGTGGTCCTCC
TCGCCGACGTCCGCTCGGTCGGCGTCCAGGGCGACGGCCGCACCTACGGCCACCCGATCGTGCTGCGCCCGGTCTCCTCC
GAGGACGCCATGACGGCCGACTGGTCGCGCCTGCCGTACGAGACGCTGGCGAAGATCTCCACCCGCATCACCAACGAGGT
CGCCGACGTCAACCGCGTCGTCCTCGACGTGACGAGCAAGCCGCCGGGGACGATCGAGTGGGAGTGA

Protein sequence :
MPAAPPAAPDTTADVVLVVDFGAQYAQLIARRVREARVYSEIVPSTMPVAEMLAKNPRAIILSGGPSSVYAEGAPSLDRS
LFEAGVPVFGMCYGFQLMATTLGGTVDDNGAREYGRTPLHVTKAGSTLFEGTPTEQPVWMSHGDACSAAPEGFTVTASTD
VVPVAAFENDEKKLYGVQYHPEVLHSTHGQQVLEHFLYRGAGIEPNWTTTNVVEEQIAAIREQVGDKRAICGLSGGVDSA
VAAALVQKAIGSQLTCVYVDHGLMRKGETEQVEKDFVAATGAKLKVVDAEKRFLDALAGVSDPEQKRKIIGREFIRVFEQ
AQLEILQEDGPEVAFLVQGTLYPDVVESGGGTGTANIKSHHNVGGLPDDIEFQLVEPLRQLFKDEVRMVGQELGLPEEIV
QRQPFPGPGLGIRIVGEVTKDRLDLLREADAIAREELTAAGLDRDIWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSS
EDAMTADWSRLPYETLAKISTRITNEVADVNRVVLDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 0.0 74
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-136 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-136 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 9e-137 52