Gene Information

Name : SFUL_3607 (SFUL_3607)
Accession : YP_007932418.1
Strain : Streptomyces fulvissimus DSM 40593
Genome accession: NC_021177
Putative virulence/resistance : Unknown
Product : Phosphomethylpyrimidine synthase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4079141 - 4080943 bp
Length : 1803 bp
Strand : +
Note : Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity); UniProt-pubmed:11572948; miscellaneous:The reacti

DNA sequence :
ATGACCACAGCGGACGCACGCACGCCTGCCTCGAAGCAGAACGACGGAACGCCGGACGGCAATCCGAACGACGAGGCCGG
GAAGTCCATCGGCTGGCACAAGGGGTACGTCCAGGGCTCGCGCCCGGACCTCCGGGTGCCGGTCCGACAGGTGCACCTCA
CCAACGGCAAGGATGTGACGCTGTACGACACGTCGGGGCCGTACACCGATCCCGGGATCGACACCGATGTCCGCCGGGGC
CTCGCGCCCCTGCGGGAGAACTGGATCATCGCCCGCGGCGACACCGAGGAGTACGCGGGCCGCCCGGTCCGCCCCGAGGA
CGACGGGCTCAAGCACACCTCGCCGCGCGGCGGACTGCGCAACCTCGACGCCGTCTTCCCCGGCCGCCCGCGCCAGCCGC
GCCGCAGCCGCGACGGACGTCCCGTCACCCAGCTCGCGTACGCCCGGCGGGGGGAGATCACCCCGGAGATGGAGTACGTC
GCGATCCGGGAGAACGTCGAGGCCGAGGTCGTCCGCGAGGAGATCGCGGCAGGCCGGGCCGTGCTGCCGGTCAACGTCAA
CCACCCCGAGATCGAGCCGATGATCATCGGCAAGCGGTTCCTGGTGAAGGTCAACGCCAACATCGGCAACTCGGCCGTCA
CCTCCTCCATCGAGGAGGAGGTGGACAAGATGACCTGGGCGACCAAGTGGGGCGCCGACACGGTCATGGACCTGTCCACC
GGCCGCAACATCCACACCACCCGTGAGTGGGTGCTGCGCAACTCCCCCGTGCCGATCGGCACCGTCCCGCTCTACCAGGC
CCTGGAGAAGGTGGACGGCCGGGCCGAGGAGCTGACCTGGGAGATCTACAAGGACACCGTCATCGAGCAGGCCGAACAGG
GCGTGGACTACATGACGGTGCACGCCGGAGTGCGCCTGCCGTACGTGCCGCTGACGGCCCGCCGTAAGACCGGCATCGTC
TCGCGCGGCGGCTCGATCATGGCGGCCTGGTGCCTGGCGCACCATAAGGAGTCGTTCCTCTACGAGCACTTCGAGGAGCT
CTGCGAGATCCTCGCGACGTACGACGTCACCTACTCCCTCGGTGACGGGCTGCGCCCCGGTTCGATCGCCGACGCCAACG
ACGAGGCGCAGTTCGCCGAGCTGCGCACGCTGGGCGAACTGAACACGATCGCCAAGCGGTTCGGCGTCCAGACGATGATC
GAGGGCCCCGGGCACGTCCCGATGCACAAGATCAAGGAGAACATCGACCTCCAGCAGGAGATCTGCGAGGAGGCGCCGTT
CTACACGCTCGGCCCGCTGACCACGGACGTCGCGCCCGCCTACGACCACATCACCTCGGGCATCGGCGCCGCGATGATCG
CCTGGTGGGGTACGGCGATGCTCTGCTACGTCACGCCCAAGGAGCACCTGGGGCTGCCCAACCGGGACGATGTGAAGACC
GGCGTCATCACCTACAAGATCGCTGCCCACGCGGCCGACCTGGCCAAGGGGCACCCGGGCGCGCAGGAGTGGGACGACGC
GCTGTCCGACGCCCGGTTCGAGTTCCGGTGGGAGGACCAGTTCAATCTGGCCCTCGACCCGGACACGGCCCGGGAGTTCC
ACGACGAGACGCTGCCCGCCGAACCGGCGAAGACGGCGCACTTCTGCTCGATGTGCGGGCCGAAGTTCTGCTCGATGAAG
ATCTCCCAGGACATCCGGCGTCAGCACGGTGGTTCGCAGGAGGAGATCGAGGAGGGCATGGCCGAGAAGTCGAAGGAGTT
CGCGGCCGCGGGCAACCGGGTCTACCTGCCGATCGCCGACTGA

Protein sequence :
MTTADARTPASKQNDGTPDGNPNDEAGKSIGWHKGYVQGSRPDLRVPVRQVHLTNGKDVTLYDTSGPYTDPGIDTDVRRG
LAPLRENWIIARGDTEEYAGRPVRPEDDGLKHTSPRGGLRNLDAVFPGRPRQPRRSRDGRPVTQLAYARRGEITPEMEYV
AIRENVEAEVVREEIAAGRAVLPVNVNHPEIEPMIIGKRFLVKVNANIGNSAVTSSIEEEVDKMTWATKWGADTVMDLST
GRNIHTTREWVLRNSPVPIGTVPLYQALEKVDGRAEELTWEIYKDTVIEQAEQGVDYMTVHAGVRLPYVPLTARRKTGIV
SRGGSIMAAWCLAHHKESFLYEHFEELCEILATYDVTYSLGDGLRPGSIADANDEAQFAELRTLGELNTIAKRFGVQTMI
EGPGHVPMHKIKENIDLQQEICEEAPFYTLGPLTTDVAPAYDHITSGIGAAMIAWWGTAMLCYVTPKEHLGLPNRDDVKT
GVITYKIAAHAADLAKGHPGAQEWDDALSDARFEFRWEDQFNLALDPDTAREFHDETLPAEPAKTAHFCSMCGPKFCSMK
ISQDIRRQHGGSQEEIEEGMAEKSKEFAAAGNRVYLPIAD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 2e-175 63
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 2e-175 63