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Name : SFUL_3281 (SFUL_3281) Accession : YP_007932100.1 Strain : Streptomyces fulvissimus DSM 40593 Genome accession: NC_021177 Putative virulence/resistance : Virulence Product : ATP-dependent chaperone ClpB Function : - COG functional category : - COG ID : - EC number : - Position : 3726307 - 3728892 bp Length : 2586 bp Strand : - Note : Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase DNA sequence : GTGGACGCCGAGCTGACCAACAAGAGCCGGGACGCCATCAACGCGGCCAGCGACCGGGCCGTGAAGGACGGGCACCCCGA CCTCACCCCCGGGCACCTGCTGCTCGCACTCCTGGCGGGTGAGGACAACGAGAACATCGTCGACCTGCTGGCCGCCGTCG AGGCCGACCAGGCCGTGGTGCGCGCCGAGACCGAGAAGCTGCTCGGGACCCTGCCCAGCGTCACCGGCTCCACCGTCGCC CCGCCGCAGCCCAACCGTGAGCTGCTGGCCGTCATCCAGGACGCGGCGCAGCGGGCGAAGGAGCTGGGCGACGAGTACCT CTCCACCGAGCACCTGCTCATCGGGATCGCCGCGAAGGGCGGGCGCGCCGGTGAGATCCTCGACGGGCAAGGGGCCACGG CCAAGAAGCTGCTGGCCGCATTCGAGACGAGCAGGGGAGGGCGTCGCGTGACCACACCCGACCCGGAGGGCCAGTACAAG GCCCTGGAGAAGTTCGGCACCGACTTCACGGCCGCCGCGCGCGAGGGCAAGCTGGACCCGGTCATCGGCCGCGACCAGGA GATCCGCCGCGTCGTGCAGGTGCTGTCGCGCCGGACGAAGAACAACCCGGTGCTCATCGGTGAGCCCGGCGTCGGCAAGA CCGCCGTCGTGGAAGGGCTCGCCCAGCGCATCGTCAAGGGCGATGTCCCGGAGAGCCTGAAGAACAAGCGGCTGGTCTCC CTCGACCTCGGCGCGATGGTCGCGGGCGCGAAGTACCGCGGCGAGTTCGAGGAGCGCCTGAAGACCGTCCTCTCCGAGAT CAAGGAGAGCGACGGCCAGATCATCACCTTCATCGACGAGCTGCACACCGTCGTCGGCGCCGGCGCGGGCGGCGACTCCG CCATGGACGCGGGCAACATGCTCAAGCCGATGCTGGCCCGCGGTGAGCTCCGCATGGTCGGCGCGACCACGCTGGACGAG TACCGCGAGCGCATCGAGAAGGACCCCGCCCTGGAGCGCCGCTTCCAGCAGGTGCTGGTCGCCGAGCCGTCCGTCGAGGA CACCATCGCGATCCTCCGCGGTCTCAAGGGCCGTTACGAGGCCCACCACAAGGTGCAGATCGCGGACTCGGCGCTGGTCG CCGCGGCCACCCTCTCCGACCGCTACATCACCTCCCGCTTCCTCCCCGACAAGGCCATCGACCTGGTCGACGAGGCCGCC TCCCGGCTCCGTATGGAGATCGACTCCTCGCCCCTGGAGATCGATGAACTCCAGCGCTCCGTAGACCGGTTGCGCATGGA GGAGCTGGCCCTGAAGAACGAGTCCGACGCCGCCTCCAAGCAGCGTCTGGAGAAGCTGCGCCGCGACCTCGCCGACAAGG AGGAGGAGCTGCGCGGCCTCAACGCCCGCTGGGAGAAGGAGAAGCAGGGCCTCAACCGGGTCGGTGAGCTCAAGGAGCGC CTGGACGAGCTGCGCGGACAGGCCGAACGAGCGCAACGCGACGGCGACTTCGACGCCGCCTCCAAGCTGCTGTACGGGGA GATCCCGGGCCTGGAGCGGGAGTTGGAGGAGGCCGCCGAGGCGGAGCAGGAAGCCTCCAAGGACACCATGGTCAAGGAGG AGGTCGGCCCGGACGACATCGCGGACGTCGTCGGCGCCTGGACCGGCATCCCGGCCGGGCGGCTGCTTGAGGGCGAGACC CAGAAGCTGCTGCGGATGGAGTCCGAGCTCGGCAAGCGGCTGATCGGCCAGAGCGAGGCGGTCCAGGCCGTCTCCGACGC CGTACGCCGTACGCGCGCCGGGATCGCCGACCCCGACCGGCCCACCGGGTCGTTCCTCTTCCTCGGCCCCACCGGCGTCG GCAAGACCGAGCTGGCCAAGGCGCTGGCGGACTTCCTCTTCGACGACGAGCGGGCCATGATCCGCATCGACATGAGCGAG TACGGCGAGAAGCACAGCGTCGCCCGCCTCGTCGGTGCCCCGCCCGGTTACGTCGGCTACGAGGAGGGCGGCCAGCTCAC CGAGGCCGTCCGCCGCCGCCCGTACAGCGTCGTGCTCCTGGACGAGGTCGAGAAGGCCCACCCCGAGGTCTTCGACATCC TGCTCCAGGTCCTCGACGACGGCCGGCTCACCGACGGCCAGGGCCGCACGGTCGACTTCCGCAACACCATCCTCGTCCTC ACCTCCAACCTCGGCAGCCAGTTCCTGATGGACCCCCTGGTCAAGCCCGAGGTCAAGAAGGAGCAGGTGCTGGACGTGGT GCGGGCCTCCTTCAAGCCGGAGTTCATCAACCGGCTGGACGACCTGGTGGTCTTCTCGGCGCTCTCCGGCGACGAGCTCG CGCACATCGCGAAGCTCCAGGTCGACCGCCTCGCGGCCCGGCTGGCCGACCGGCGTCTGACCCTCGACGTCACCCCCGAG GCGCTGGCCTGGCTCGCCGAGGAGGGCAACGATCCGGCGTACGGGGCGCGCCCGCTGCGCCGCCTCATCCAGACGGCGAT CGGCGACCGGCTCGCCAAGGAGATCCTCTCCGGCGAGATCACGGACGGTGACACCGTGCGGGTGGACCGGGCCGAGGACG GACTGATCGTCGGCCCGGCCTCGTGA Protein sequence : MDAELTNKSRDAINAASDRAVKDGHPDLTPGHLLLALLAGEDNENIVDLLAAVEADQAVVRAETEKLLGTLPSVTGSTVA PPQPNRELLAVIQDAAQRAKELGDEYLSTEHLLIGIAAKGGRAGEILDGQGATAKKLLAAFETSRGGRRVTTPDPEGQYK ALEKFGTDFTAAAREGKLDPVIGRDQEIRRVVQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQRIVKGDVPESLKNKRLVS LDLGAMVAGAKYRGEFEERLKTVLSEIKESDGQIITFIDELHTVVGAGAGGDSAMDAGNMLKPMLARGELRMVGATTLDE YRERIEKDPALERRFQQVLVAEPSVEDTIAILRGLKGRYEAHHKVQIADSALVAAATLSDRYITSRFLPDKAIDLVDEAA SRLRMEIDSSPLEIDELQRSVDRLRMEELALKNESDAASKQRLEKLRRDLADKEEELRGLNARWEKEKQGLNRVGELKER LDELRGQAERAQRDGDFDAASKLLYGEIPGLERELEEAAEAEQEASKDTMVKEEVGPDDIADVVGAWTGIPAGRLLEGET QKLLRMESELGKRLIGQSEAVQAVSDAVRRTRAGIADPDRPTGSFLFLGPTGVGKTELAKALADFLFDDERAMIRIDMSE YGEKHSVARLVGAPPGYVGYEEGGQLTEAVRRRPYSVVLLDEVEKAHPEVFDILLQVLDDGRLTDGQGRTVDFRNTILVL TSNLGSQFLMDPLVKPEVKKEQVLDVVRASFKPEFINRLDDLVVFSALSGDELAHIAKLQVDRLAARLADRRLTLDVTPE ALAWLAEEGNDPAYGARPLRRLIQTAIGDRLAKEILSGEITDGDTVRVDRAEDGLIVGPAS |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| STY0294 | NP_454876.1 | ClpB-like protein | Not tested | SPI-6 | Protein | 1e-100 | 42 |
| aec27 | AAQ96721.1 | Aec27 | Not tested | AGI-1 | Protein | 5e-98 | 41 |
| aec27 | YP_851418.1 | ATPase | Not tested | PAI II APEC-O1 | Protein | 7e-98 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| SFUL_3281 | YP_007932100.1 | ATP-dependent chaperone ClpB | VFG2076 | Protein | 2e-114 | 45 |
| SFUL_3281 | YP_007932100.1 | ATP-dependent chaperone ClpB | VFG2084 | Protein | 7e-105 | 42 |
