Gene Information

Name : SFUL_1559 (SFUL_1559)
Accession : YP_007930412.1
Strain : Streptomyces fulvissimus DSM 40593
Genome accession: NC_021177
Putative virulence/resistance : Virulence
Product : Pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 1753624 - 1755063 bp
Length : 1440 bp
Strand : -
Note : UniProt-pubmed:11572948; UniProt-pubmed:20624727; pathway_coverage:01.03.01.35 GTP generation from GDP; gene_name:pykA2; pathway_coverage:02.01.02.01 standard path; UniProt-pubmed:21463507; UniProt-pubmed:18375553; pathway:Carbohydrate degradation; glycol

DNA sequence :
ATGCGCCGAGCGAAAATCGTTTGTACCCTGGGACCGGCAACCGACACATACGACCAGATCAAGGCCCTGGTCGAAGCGGG
AATGGACATCGCCCGCTTCAACCTCAGCCACGGCTCCTACGCCGAACACGAGCAGCGATACCACCACGTCCGCAAAGCCT
CCGAAGAGACCGGCCGCAGCGTCGGCATCCTCGCCGACCTTCAAGGCCCGAAGATCCGCCTCGGACGCTTCCGCGAAGGC
CCCGTACTCCTTGAACGCGGCGACACCTTCACCATCACCGTCGAACCCCTCGAAAACGAAGGCAACGGCGACATCTGCGG
CACCACCTACGACGGCCTCGCCGCCGACGTCACCACCGGCGAACGCATCCTCGTCGACGACGGCCGCGTCACCCTCGAAG
TCACCGACGTCGACGGCCCCCGCGTCCACACCACCGTCATCGAAGGCGGCATGGTCTCCGACAACAAGGGCCTCAACCTC
CCCGGCGTCGCCGTCTCCGTCCCCGCCCTCTCCGAGAAGGACATCGACGACCTCCGCTGGGCCCTGCGCACCGGCGCCGA
CCTCATCGCCCTCTCCTTCGTCCGCACCGGACGCGACATCGACGACGTCCACCGCATCATGGACGAGGAAGGCCGCCGCC
TCCCCGTCATCGCCAAGGTCGAGAAACCCCAGGCCGTCGAGAACATCGACGACATCGTCGCCGCCTTCGACGGCATCATG
GTCGCCCGCGGCGACCTCGGCGTCGAAATGCCCCTGGAACAGGTCCCGATCGTCCAGAAGCGCGCCATCAAACTCGCCAA
GCGCAACGCCAAGCCGGTCATCGTCGCCACCCAGATGCTCGACTCGATGATCGACAACTCCCGCCCCACCCGCGCCGAAG
CCTCCGACGTCGCCAACGCGATCATCGACGGCACCGACGCGGTGATGCTCTCCGGCGAGACCAGCGTCGGCAAGTACCCC
ATCGAGACCGTGCGCACCATGTCCCGCATCGTCGAAGCGGCCGAGGAAGACATCCTCGCCAAGGGCCTCCCGCCCCTCAC
CGACCGCAACAAGCCCCGCACCCAGGGCGGCGCCGTCGCGAGGGCCGCCGCCGAGATGGGCGACTTCCTCGGCGCGAAGT
TCCTCGTCGCCTTCACCCAGAGCGGCGACACGGTCAAGCGCCTCTCCCGCTACCGCTCACCCATCCCGCTCCTCGCCTTC
ACCCCCGACGAAGCGACCCGCGCCCAGCTCAACCTCACCTGGGGCGTCGAGACCTTCCTCGGCCCGCACGTCGACTCCAC
GGACGCGATGGTCGCCCAGGTCGACGAGGAACTCCTGCGCATCGGCCGCTGCGCGAAGGGCGACATCGTGGTGATCACCG
CCGGCTCCCCGCCCGGCGTAGCCGGCTCCACCAACCTGGTCCGCGTCCACCACATCGGCGAGGACGACAGCCCGAAGTAG

Protein sequence :
MRRAKIVCTLGPATDTYDQIKALVEAGMDIARFNLSHGSYAEHEQRYHHVRKASEETGRSVGILADLQGPKIRLGRFREG
PVLLERGDTFTITVEPLENEGNGDICGTTYDGLAADVTTGERILVDDGRVTLEVTDVDGPRVHTTVIEGGMVSDNKGLNL
PGVAVSVPALSEKDIDDLRWALRTGADLIALSFVRTGRDIDDVHRIMDEEGRRLPVIAKVEKPQAVENIDDIVAAFDGIM
VARGDLGVEMPLEQVPIVQKRAIKLAKRNAKPVIVATQMLDSMIDNSRPTRAEASDVANAIIDGTDAVMLSGETSVGKYP
IETVRTMSRIVEAAEEDILAKGLPPLTDRNKPRTQGGAVARAAAEMGDFLGAKFLVAFTQSGDTVKRLSRYRSPIPLLAF
TPDEATRAQLNLTWGVETFLGPHVDSTDAMVAQVDEELLRIGRCAKGDIVVITAGSPPGVAGSTNLVRVHHIGEDDSPK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 7e-82 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 4e-82 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 4e-82 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-81 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SFUL_1559 YP_007930412.1 Pyruvate kinase VFG0479 Protein 2e-82 43