Gene Information

Name : SFUL_2 (SFUL_2)
Accession : YP_007928872.1
Strain : Streptomyces fulvissimus DSM 40593
Genome accession: NC_021177
Putative virulence/resistance : Resistance
Product : Beta-lactamase
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.2.6
Position : 373 - 1353 bp
Length : 981 bp
Strand : -
Note : Beta-lactamase with a substrate specificity for penicillins; UniProt-pubmed:21317323; UniProt-pubmed:21515778; UniProt-pubmed:21167037; gene_name:penP; UniProt-pubmed:9384377; subcellular_location:Secreted; UniProt-pubmed:21551302; UniProt-pubmed:10658653

DNA sequence :
GTGCCCACCCGTACCGCCGCGTCCACCCGCACTCCCGCCCATGTCTCCCGCCGGTCCGCACTCGCCGCACTGGCCGGTGC
CGCCCTGCTCCCGCTCACCGGCTGTTCGACGGCCGGACCGGATACCGCCACCGACGGGAGGAGCGGGCCGAGCCGTTCCG
GCCCCGGGCCCTCGCCGTCCGCCTCGGCCCTGCCCCGTACGGACCGCGCCTTCGCCGGACTGGAGCGGAAGTTCGACGCC
CGGCTGGGCGTGTACGCGGTCGACACCGGCGACGGACGGATCGTCGCCCACCGCCCCGACGAACGGTTCGCCTACGCCTC
CACCTGCAAGGCCCTCCTCGCCGGGGCCGTACTGGCCAAGAAGAGCCTCCCGCAGATGGAGCGCCTCGTCCGCTACGGCG
AGGAGGAGATCATCAGCAACTCGCCCATCACCGAGAAGCATGTCGCCACCGGCATGACCCTGCGCGAACTGTGCGACGCC
GCCATCCGCTACAGCGACAACGCCGCCGCCAACCTGCTCTTCCGCGAACTGGGCGGCCCCCGAGGCCTCCAGGACGCCCT
GCGCGGACTCGGGGACCGCATCACCCGCTGCGACCGCTACGAAGTCGCCCTCAGCGATGCGACCCCCGGCGACCTCCGTG
ACACCAGCACACCCCGCGCCCTGGCCACGGACCTGCGTGCGTACGTCCTCGGGCCGGCCCTCCCCGCCGGGAAGCAGGCC
GTGCTCGCCGACTGGCTGAAGCGCAACACCACCGGCGACCACACCATCCGCGCGGGCACACCCCGCGGATGGGAGGTCGG
AGACAAGACCGGCACCGGCGGCTACGGGACCCGTAACGACATCGCCATCGTCCGGCCTCCGGGCGGCGCCGCCCCGATCG
CGCTCGCCGTTCTCTCCCGGCGCGACACCAAGGACGCCGAACCTCAGGACGCCCTGATCGCCGGAGCCGCGAAGGTCGCC
CTCGAAGCGTTCGCCTACTGA

Protein sequence :
MPTRTAASTRTPAHVSRRSALAALAGAALLPLTGCSTAGPDTATDGRSGPSRSGPGPSPSASALPRTDRAFAGLERKFDA
RLGVYAVDTGDGRIVAHRPDERFAYASTCKALLAGAVLAKKSLPQMERLVRYGEEEIISNSPITEKHVATGMTLRELCDA
AIRYSDNAAANLLFRELGGPRGLQDALRGLGDRITRCDRYEVALSDATPGDLRDTSTPRALATDLRAYVLGPALPAGKQA
VLADWLKRNTTGDHTIRAGTPRGWEVGDKTGTGGYGTRNDIAIVRPPGGAAPIALAVLSRRDTKDAEPQDALIAGAAKVA
LEAFAY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
blaCTX-M2 ACF06162.1 beta-lactamase CTX-M2 Not tested Tn5036-like Protein 2e-37 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SFUL_2 YP_007928872.1 Beta-lactamase AF367983.gene.p01 Protein 1e-66 55
SFUL_2 YP_007928872.1 Beta-lactamase AF395881.gene.p01 Protein 3e-45 50
SFUL_2 YP_007928872.1 Beta-lactamase FJ234412.1.gene1.p01 Protein 6e-46 50
SFUL_2 YP_007928872.1 Beta-lactamase GQ140348.1.gene1.p01 Protein 5e-45 50
SFUL_2 YP_007928872.1 Beta-lactamase EU729727.1.gene1.p1 Protein 2e-45 50
SFUL_2 YP_007928872.1 Beta-lactamase AY034847.1.gene1.p01 Protein 9e-46 49
SFUL_2 YP_007928872.1 Beta-lactamase EU555534.1.gene1.p01 Protein 2e-46 49
SFUL_2 YP_007928872.1 Beta-lactamase AF297554.1.gene1.p1 Protein 2e-45 49
SFUL_2 YP_007928872.1 Beta-lactamase HQ641421.1.gene1.p01 Protein 1e-45 49
SFUL_2 YP_007928872.1 Beta-lactamase HM066995.1.gene1.p01 Protein 2e-45 49
SFUL_2 YP_007928872.1 Beta-lactamase AF325134.1.gene1.p1 Protein 1e-38 45
SFUL_2 YP_007928872.1 Beta-lactamase AY143430.1.gene1.p01 Protein 2e-38 45
SFUL_2 YP_007928872.1 Beta-lactamase AY156923.1.gene1.p01 Protein 4e-39 45
SFUL_2 YP_007928872.1 Beta-lactamase AY847146.1.gene1.p01 Protein 2e-38 45
SFUL_2 YP_007928872.1 Beta-lactamase HQ913565.1.gene1.p01 Protein 1e-38 45
SFUL_2 YP_007928872.1 Beta-lactamase JF274246.1.gene1.p01 Protein 4e-38 45
SFUL_2 YP_007928872.1 Beta-lactamase HM803271.1.gene1.p01 Protein 2e-38 45
SFUL_2 YP_007928872.1 Beta-lactamase AF252622.2.gene2.p01 Protein 1e-38 45
SFUL_2 YP_007928872.1 Beta-lactamase AY822595.1.gene1.p01 Protein 3e-38 45
SFUL_2 YP_007928872.1 Beta-lactamase HQ398215.1.gene1.p01 Protein 7e-39 45
SFUL_2 YP_007928872.1 Beta-lactamase JF274247.1.gene1.p01 Protein 2e-38 45
SFUL_2 YP_007928872.1 Beta-lactamase HM755448.1.gene1.p01 Protein 5e-39 45
SFUL_2 YP_007928872.1 Beta-lactamase FJ214366.1.gene1.p1 Protein 2e-38 45
SFUL_2 YP_007928872.1 Beta-lactamase AF252623.2.gene1.p01 Protein 4e-38 45
SFUL_2 YP_007928872.1 Beta-lactamase FJ214367.1.gene1.p1 Protein 1e-38 45
SFUL_2 YP_007928872.1 Beta-lactamase AY847144.1.gene1.p01 Protein 1e-38 45
SFUL_2 YP_007928872.1 Beta-lactamase EF581888.1.gene1.p01 Protein 1e-38 45
SFUL_2 YP_007928872.1 Beta-lactamase AY847147.1.gene1.p01 Protein 2e-38 45
SFUL_2 YP_007928872.1 Beta-lactamase AY029068.1.gene1.p1 Protein 1e-38 45
SFUL_2 YP_007928872.1 Beta-lactamase AY847143.1.gene1.p01 Protein 3e-38 45
SFUL_2 YP_007928872.1 Beta-lactamase HQ833652.1.gene1.p01 Protein 2e-38 45
SFUL_2 YP_007928872.1 Beta-lactamase AY847145.1.gene1.p01 Protein 6e-38 45
SFUL_2 YP_007928872.1 Beta-lactamase AF325133.1.gene1.p1 Protein 1e-38 45
SFUL_2 YP_007928872.1 Beta-lactamase HQ166709.1.gene1.p01 Protein 3e-38 45
SFUL_2 YP_007928872.1 Beta-lactamase JF274242.1.gene1.p01 Protein 8e-38 45
SFUL_2 YP_007928872.1 Beta-lactamase AY033516.1.gene2.p01 Protein 2e-38 45
SFUL_2 YP_007928872.1 Beta-lactamase AB205197.1.gene1.p01 Protein 6e-37 44
SFUL_2 YP_007928872.1 Beta-lactamase AY750914.gene.p01 Protein 1e-36 44
SFUL_2 YP_007928872.1 Beta-lactamase FJ907381.1.gene1.p01 Protein 2e-38 44
SFUL_2 YP_007928872.1 Beta-lactamase AF174129.3.gene9.p01 Protein 4e-38 44
SFUL_2 YP_007928872.1 Beta-lactamase AB284167.2.gene1.p01 Protein 1e-38 44
SFUL_2 YP_007928872.1 Beta-lactamase AY303807.gene.p01 Protein 1e-36 44
SFUL_2 YP_007928872.1 Beta-lactamase HQ833651.1.gene1.p01 Protein 8e-39 44
SFUL_2 YP_007928872.1 Beta-lactamase FJ214369.1.gene1.p1 Protein 5e-38 44
SFUL_2 YP_007928872.1 Beta-lactamase EU136031.3.gene1.p3 Protein 1e-38 44
SFUL_2 YP_007928872.1 Beta-lactamase EF418608.1.gene1.p01 Protein 3e-38 44
SFUL_2 YP_007928872.1 Beta-lactamase AJ416345.gene.p01 Protein 4e-38 44
SFUL_2 YP_007928872.1 Beta-lactamase JF274243.1.gene1.p01 Protein 6e-38 44
SFUL_2 YP_007928872.1 Beta-lactamase FJ214368.1.gene1.p1 Protein 1e-37 44
SFUL_2 YP_007928872.1 Beta-lactamase EU545409.1.gene1.p1 Protein 6e-39 44
SFUL_2 YP_007928872.1 Beta-lactamase DQ211987.1.gene1.p01 Protein 5e-38 44
SFUL_2 YP_007928872.1 Beta-lactamase AF189721.1.gene1.p01 Protein 3e-37 44
SFUL_2 YP_007928872.1 Beta-lactamase HM167760.1.gene1.p01 Protein 6e-36 43
SFUL_2 YP_007928872.1 Beta-lactamase AY157676.1.gene1.p01 Protein 2e-35 43
SFUL_2 YP_007928872.1 Beta-lactamase AM982522.2.gene1.p01 Protein 2e-35 43
SFUL_2 YP_007928872.1 Beta-lactamase AF275256.gene.p01 Protein 8e-39 43
SFUL_2 YP_007928872.1 Beta-lactamase Z28968.gene.p01 Protein 4e-37 43
SFUL_2 YP_007928872.1 Beta-lactamase GQ351346.1.gene1.p01 Protein 9e-37 42
SFUL_2 YP_007928872.1 Beta-lactamase GQ870432.1.gene1.p1 Protein 7e-35 42
SFUL_2 YP_007928872.1 Beta-lactamase DQ023162.1.gene1.p1 Protein 5e-35 42
SFUL_2 YP_007928872.1 Beta-lactamase FJ971899.1.gene1.p1 Protein 7e-35 42
SFUL_2 YP_007928872.1 Beta-lactamase AY954516.1.gene1.p1 Protein 6e-35 42
SFUL_2 YP_007928872.1 Beta-lactamase AF518567.2.gene4.p01 Protein 2e-35 42
SFUL_2 YP_007928872.1 Beta-lactamase DQ663489.gene.p01 Protein 9e-35 42
SFUL_2 YP_007928872.1 Beta-lactamase U50278.1.gene2.p01 Protein 4e-37 42
SFUL_2 YP_007928872.1 Beta-lactamase DQ102702.1.gene1.p1 Protein 1e-37 41
SFUL_2 YP_007928872.1 Beta-lactamase DQ223685.1.gene1.p01 Protein 3e-36 41
SFUL_2 YP_007928872.1 Beta-lactamase AJ416344.1.gene1.p01 Protein 2e-37 41
SFUL_2 YP_007928872.1 Beta-lactamase AY238472.1.gene1.p01 Protein 7e-37 41
SFUL_2 YP_007928872.1 Beta-lactamase GQ149244.1.gene1.p01 Protein 2e-37 41
SFUL_2 YP_007928872.1 Beta-lactamase U95364.1.gene1.p01 Protein 6e-38 41
SFUL_2 YP_007928872.1 Beta-lactamase FJ873739.1.gene1.p01 Protein 4e-37 41
SFUL_2 YP_007928872.1 Beta-lactamase X92507.1.gene1.p01 Protein 1e-37 41
SFUL_2 YP_007928872.1 Beta-lactamase DQ885477.1.gene1.p01 Protein 1e-36 41
SFUL_2 YP_007928872.1 Beta-lactamase JF966749.1.gene1.p01 Protein 5e-36 41
SFUL_2 YP_007928872.1 Beta-lactamase HQ398214.1.gene1.p01 Protein 2e-36 41
SFUL_2 YP_007928872.1 Beta-lactamase EF374097.1.gene1.p01 Protein 1e-37 41
SFUL_2 YP_007928872.1 Beta-lactamase AY995206.gene.p01 Protein 9e-37 41
SFUL_2 YP_007928872.1 Beta-lactamase EU402393.1.gene1.p1 Protein 4e-36 41
SFUL_2 YP_007928872.1 Beta-lactamase AJ567481.1.gene1.p01 Protein 2e-37 41
SFUL_2 YP_007928872.1 Beta-lactamase AJ549244.1.gene1.p01 Protein 2e-36 41
SFUL_2 YP_007928872.1 Beta-lactamase GQ149243.1.gene1.p01 Protein 9e-38 41
SFUL_2 YP_007928872.1 Beta-lactamase AF488377.1.gene1.p1 Protein 3e-36 41
SFUL_2 YP_007928872.1 Beta-lactamase HM776707.1.gene1.p1 Protein 2e-37 41
SFUL_2 YP_007928872.1 Beta-lactamase EF210159.1.gene1.p01 Protein 2e-36 41
SFUL_2 YP_007928872.1 Beta-lactamase DQ125241.gene.p01 Protein 1e-37 41
SFUL_2 YP_007928872.1 Beta-lactamase DQ810789.1.gene1.p01 Protein 1e-36 41
SFUL_2 YP_007928872.1 Beta-lactamase DQ268764.2.gene6.p01 Protein 6e-36 41
SFUL_2 YP_007928872.1 Beta-lactamase EF219142.1.gene1.p01 Protein 2e-36 41
SFUL_2 YP_007928872.1 Beta-lactamase X92506.gene.p01 Protein 4e-36 41
SFUL_2 YP_007928872.1 Beta-lactamase DQ408762.1.gene1.p1 Protein 2e-38 41
SFUL_2 YP_007928872.1 Beta-lactamase EF426798.1.gene1.p1 Protein 2e-36 41
SFUL_2 YP_007928872.1 Beta-lactamase AM411407.1.gene1.p01 Protein 3e-36 41
SFUL_2 YP_007928872.1 Beta-lactamase AF305837.gene.p01 Protein 2e-36 41
SFUL_2 YP_007928872.1 Beta-lactamase AJ704396.1.gene1.p01 Protein 9e-37 41
SFUL_2 YP_007928872.1 Beta-lactamase AY267213.1.gene1.p01 Protein 1e-36 41
SFUL_2 YP_007928872.1 Beta-lactamase AJ557142.gene.p01 Protein 1e-36 41
SFUL_2 YP_007928872.1 Beta-lactamase DQ328639.gene.p01 Protein 1e-35 41