Gene Information

Name : TY21A_22985 (TY21A_22985)
Accession : YP_007928753.1
Strain : Salmonella enterica Ty21a
Genome accession: NC_021176
Putative virulence/resistance : Unknown
Product : integrase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4666739 - 4668004 bp
Length : 1266 bp
Strand : +
Note : COG0582 Integrase

DNA sequence :
ATGAAGCTCAACGCCAGACAGGTCGAGACCGCAAAGCCAAAAGACAAAACCTACAAAATGGCCGATGGCGGCGGTTTGTA
CCTTGAGGTTTCGGCCAAGGGATCCAAATACTGGCGCATGAAATACAGACGCCCCTCTGACAAAAAAGAGGATCGCCTCG
CTTTTGGTGTTTGGCCTACTGTGACACTTGCTCAGGCAAGAGCAAAGCGCGATGAAGCCAAAAAGTTGCTAGTGCAGGGC
ATTGATCCAAAAACCGAACAGAAAGAGGCTCAGGCCGAGAACTCGGGGGCGTATACTTTCGAAACTATCGCTCGTGAATG
GCATGCCAGTAACAAGCGCTGGAGCGAAGACCATCGATCGCGCGTTCTTCGCTATCTTGAACTTTATATTTTCCCTCATA
TCGGTTCGTCCGACATTCGCCAGCTCAAAACCAGTCACCTGTTAGCCCCGATCAAAAAAGTTGATGCCAGTGGTAAACAC
GACGTCGCTCAGCGCCTGCAACAGCGCGTCACGGCTATTATGCGTTATGCCGTACAGAACGATTACATCGACTCTAATCC
AGCCAGTGACATGGCCGGTGCGTTATCGACTACCAAAGCACGACACTATCCAGCCTTACCTTCTAGCCGTTTCCCTGAGT
TTCTTGCTCGCCTTGCTGCATATCGTGGCCGTGTAATGACACGGATTGCTGTCGAGCTTTCCTTACTAACTTTTGTACGT
TCCAGCGAGTTACGTTTCGCGCGTTGGGACGAGTTCGACTTCGATAAATCCCTTTGGCGCGTACCGGCAAAACGAGAAGA
AATTAAGGGTGTGCGTTATTCGTACCGTGGCATGAAGATGAAAGAGGAGCATATCGTTCCTCTCAGTCGGCAGGCGATGG
TTTTGTTAGAGCAGCTCAAGCAGATTAGTGGTGATAAAGAGCTGTTGTTTCCGGGGGATCACGACGCAACTAAGGTTATG
AGCGAAAACACGGTAAATAGCGCATTGCGTGCGATGGGTTATGACACAAAAACCGAGGTCTGCGGGCATGGGTTTCGGAC
GATGGCGCGTGGTGCTTTGGGTGAGTCAGGATTATGGAGCGATGACGCGATAGAGCGTCAGTTAAGCCATTCTGAGCGTA
ACAATGTGCGTGCTGCCTATATTCACACTTCAGAGCATTTGGATGAGCGTCGTTTGATGGTGCAGTGGTGGGCTGATTAT
CTCGATATTATTCAGTATGAGCATATTACACCTTATGAATATGCAAGAGTCTGCAACATAAAATGA

Protein sequence :
MKLNARQVETAKPKDKTYKMADGGGLYLEVSAKGSKYWRMKYRRPSDKKEDRLAFGVWPTVTLAQARAKRDEAKKLLVQG
IDPKTEQKEAQAENSGAYTFETIAREWHASNKRWSEDHRSRVLRYLELYIFPHIGSSDIRQLKTSHLLAPIKKVDASGKH
DVAQRLQQRVTAIMRYAVQNDYIDSNPASDMAGALSTTKARHYPALPSSRFPEFLARLAAYRGRVMTRIAVELSLLTFVR
SSELRFARWDEFDFDKSLWRVPAKREEIKGVRYSYRGMKMKEEHIVPLSRQAMVLLEQLKQISGDKELLFPGDHDATKVM
SENTVNSALRAMGYDTKTEVCGHGFRTMARGALGESGLWSDDAIERQLSHSERNNVRAAYIHTSEHLDERRLMVQWWADY
LDIIQYEHITPYEYARVCNIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY4821 NP_458899.1 integrase Not tested SPI-10 Protein 0.0 100
intB CAD42017.1 bacteriophage P4 integrase Not tested PAI II 536 Protein 3e-112 59
S4822 NP_838459.1 P4-type integrase Not tested SHI-1 Protein 2e-116 55
SF2964 NP_708738.1 P4-type integrase Not tested SHI-1 Protein 2e-116 55
int AAK00456.1 Int Not tested SHI-1 Protein 5e-109 55
ECUMN_3322 YP_002414004.1 integrase Not tested Not named Protein 2e-116 55
int AAK16198.1 Int Not tested PAI-I AL862 Protein 4e-116 55
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 4e-116 55
int NP_458759.1 bacteriophage integrase Not tested SPI-7 Protein 4e-111 55
int NP_807963.1 bacteriophage integrase Not tested SPI-7 Protein 4e-111 55
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 5e-113 55
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 5e-113 55
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 3e-114 54
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 4e-116 54
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 5e-116 54
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 2e-116 54
int AAL51028.1 CP4-like integrase Not tested LEE Protein 5e-116 54
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 2e-116 54
int-phe AAL60261.1 Int-phe Not tested LEE Protein 5e-116 54
ECO103_3550 YP_003223418.1 integrase Not tested LEE Protein 7e-116 54
ECO26_5300 YP_003232178.1 integrase Not tested LEE Protein 7e-116 54
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 2e-115 54
int AAL51003.1 CP4-like integrase Not tested LEE Protein 2e-115 54
intP4 CAE85151.1 CP4 integrase protein Not tested PAI V 536 Protein 5e-116 54
int-phe AAL57571.1 CP4-like integrase Not tested LEE Protein 5e-116 54
int CAC81896.1 integrase Not tested LEE II Protein 2e-108 54
Z4313 NP_289539.1 pathogenicity island integrase Not tested OI-122 Protein 4e-115 53
APECO1_1051 YP_853069.1 phage integrase Not tested PAI IV APEC-O1 Protein 5e-75 50
intB AAD37509.1 P4-like integrase Not tested PAI IV 536 Protein 8e-86 49
int YP_002346908.1 integrase Not tested HPI Protein 5e-98 48
y2393 NP_669700.1 prophage integrase Not tested HPI Protein 5e-98 48
int2 NP_993013.1 integrase Not tested HPI Protein 5e-98 48
int CAB59974.1 integrase Not tested HPI Protein 2e-98 48
int CAA21384.1 - Not tested HPI Protein 5e-98 48
int CAA08754.1 integrase Not tested HPI Protein 1e-98 48
unnamed ABR13507.1 phage integrase Not tested PAGI-6 Protein 2e-93 48
unnamed AAD17660.1 unknown Not tested HPI Protein 7e-95 47
int CAC39282.1 integrase Not tested LPA Protein 8e-76 44
aec33 AAW51716.1 Int Not tested AGI-3 Protein 8e-76 44
int AAD44730.1 Int Not tested SHI-2 Protein 2e-75 44
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 1e-74 44
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 1e-74 44
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 1e-74 44
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 1e-73 43
int AAC31482.1 CP4-like integrase Not tested LEE Protein 9e-74 43
int ACU09430.1 integrase Not tested LEE Protein 9e-74 43
ECs4534 NP_312561.1 integrase Not tested LEE Protein 1e-73 43
ESA_03025 YP_001439090.1 hypothetical protein Not tested Not named Protein 8e-74 43
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 1e-72 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TY21A_22985 YP_007928753.1 integrase VFG1536 Protein 2e-112 59
TY21A_22985 YP_007928753.1 integrase VFG0626 Protein 1e-116 55
TY21A_22985 YP_007928753.1 integrase VFG1693 Protein 8e-117 54
TY21A_22985 YP_007928753.1 integrase VFG0598 Protein 6e-75 44
TY21A_22985 YP_007928753.1 integrase VFG0783 Protein 5e-74 43