Gene Information

Name : TY21A_22165 (TY21A_22165)
Accession : YP_007928593.1
Strain : Salmonella enterica Ty21a
Genome accession: NC_021176
Putative virulence/resistance : Virulence
Product : Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4505424 - 4506701 bp
Length : 1278 bp
Strand : -
Note : COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase

DNA sequence :
GTGTTCGGTATAGACGAGGTAAAAATCGCGATTATTGGGCTGGGATATGTTGGGCTTCCTCTGGCAGTTGAATTTGGCAA
ATCTCGTCAGGTTGTTGGCTTCGACGTTAATAAAAAGCGTATTCTTGAATTAAAGAATGGGGTGGATGTCAATCTGGAAA
CCACTGAAGAAGAATTACGTGAGGCTCGTTATCTGAAATTTACTTCCGAGATTGAGAAGATCAAAGAATGTAATTTTTAC
ATCATCACCGTCCCGACGCCGATAAATACCTACAAGCAACCAGACCTCACCCCACTAATCAAGGCGAGTGAAACCGTTGG
TACAGTGCTGAATCGGGGAGATATTGTGGTATATGAATCTACGGTATATCCGGGATGTACCGAAGAAGAATGCGTGCCGA
TCCTTGCTCGTATGTCCGGAATGACTTTCAACCAGGATTTCTATGTCGGTTATAGCCCGGAAAGGATCAATCCCGGTGAT
AAAAAGCACCGTTTAACCAACATCAAGAAAATCACCTCCGGTTCAACCGCACAGATCGCCGAACTTATCGATGAAGTATA
TCAGCAGATCATCAGCGCAGGTACATATAAAGCAGAGAGCATCAAAGTTGCTGAGGCAGCGAAGGTGATTGAAAATACGC
AACGCGATCTGAATATTGCCTTGGTCAATGAGCTGGCGATTATTTTTAATCGTTTAAATATCGATACTGAAGCCGTGCTA
CGTGCCGCTGGCAGCAAATGGAATTTCCTGCCATTCCGTCCGGGACTGGTCGGTGGTCACTGTATTGGCGTAGATCCCTA
TTATCTGACACATAAATCTCAGGGCATTGGCTATTATCCAGAAATCATACTTGCAGGACGCCGCCTGAACGACAACATGG
GCAACTATGTCTCCGAGCAGTTGATCAAAGCAATGATCAAAAAAGGAATTAACGTTGAGGGTTCCAGCGTGCTGATTCTC
GGCTTTACCTTTAAAGAAAACTGTCCGGACATCAGAAATACACGCATTATTGATGTGGTAAAGGAACTCGGTAAATATAG
TTGTAAAGTGGATATTTTTGATCCATGGGTGGATGCCGAAGAGGTAAGACGAGAGTATGGCATTATCCCGGTATCGGAAG
TCAAATCAAGCCACTACGATGCGATCATTGTTGCAGTAGGACATCAGCAATTTAAACAGATGGGAAGTGAGGATATTCGC
GGCTTCGGAAAAGATAAACATGTACTTTATGATTTGAAGTATGTTCTTCCGGCTGAGCAGTCAGATGTGAGATTGTAA

Protein sequence :
MFGIDEVKIAIIGLGYVGLPLAVEFGKSRQVVGFDVNKKRILELKNGVDVNLETTEEELREARYLKFTSEIEKIKECNFY
IITVPTPINTYKQPDLTPLIKASETVGTVLNRGDIVVYESTVYPGCTEEECVPILARMSGMTFNQDFYVGYSPERINPGD
KKHRLTNIKKITSGSTAQIAELIDEVYQQIISAGTYKAESIKVAEAAKVIENTQRDLNIALVNELAIIFNRLNIDTEAVL
RAAGSKWNFLPFRPGLVGGHCIGVDPYYLTHKSQGIGYYPEIILAGRRLNDNMGNYVSEQLIKAMIKKGINVEGSSVLIL
GFTFKENCPDIRNTRIIDVVKELGKYSCKVDIFDPWVDAEEVRREYGIIPVSEVKSSHYDAIIVAVGHQQFKQMGSEDIR
GFGKDKHVLYDLKYVLPAEQSDVRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 0.0 100
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 0.0 100
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 6e-105 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TY21A_22165 YP_007928593.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase VFG0431 Protein 0.0 100