Gene Information

Name : TY21A_14135 (TY21A_14135)
Accession : YP_007927069.1
Strain : Salmonella enterica Ty21a
Genome accession: NC_021176
Putative virulence/resistance : Virulence
Product : invasion protein InvA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2876257 - 2878314 bp
Length : 2058 bp
Strand : -
Note : COG4789 Type III secretory pathway, component EscV

DNA sequence :
GTGCTGCTTTCTCTACTTAACAGTGCTCGTTTACGACCTGAATTACTGATTCTGGTACTAATGGTGATGATCATTTCTAT
GTTCGTCATTCCATTACCTACCTATCTGGTTGATTTCCTGATCGCACTGAATATCGTACTGGCGATATTGGTGTTTATGG
GGTCGTTCTACATTGACAGAATCCTCAGTTTTTCAACGTTTCCTGCGGTACTGTTAATTACCACGCTCTTTCGTCTGGCA
TTATCGATCAGTACCAGCCGTCTTATCTTGATTGAAGCCGATGCCGGTGAAATTATCGCCACGTTCGGGCAATTCGTTAT
TGGCGATAGCCTGGCGGTGGGTTTTGTTGTCTTCTCTATTGTCACCGTGGTCCAGTTTATCGTTATTACCAAAGGTTCAG
AACGCGTCGCGGAAGTCGCGGCCCGATTTTCTCTGGATGGTATGCCCGGTAAACAGATGAGTATTGATGCCGATTTGAAG
GCCGGTATTATTGATGCGGATGCTGCGCGCGAACGGCGAAGCGTACTGGAAAGGGAAAGCCAGCTTTACGGTTCCTTTGA
CGGTGCGATGAAGTTTATCAAAGGTGACGCTATTGCCGGCATCATTATCATCTTTGTGAACTTTATTGGCGGTATTTCGG
TGGGGATGACCCGCCATGGTATGGATTTGTCCTCCGCTCTGTCTACTTATACCATGCTGACCATTGGTGATGGTCTTGTC
GCCCAGATCCCCGCATTGTTGATTGCGATTAGTGCCGGTTTTATCGTGACTCGCGTAAATGGCGATAGCGATAATATGGG
GCGGAATATCATGACGCAGCTGTTGAACAACCCATTTGTATTGGTTGTTACGGCTATTTTGACCATTTCAATGGGAACTC
TGCCGGGATTCCCGCTGCCGGTATTTGTTATTTTATCGGTGGTTTTAAGCGTACTCTTCTATTTTAAATTCCGTGAAGCA
AAACGTAGCGCCGCCAAACCTAAAACCAGCAAAGGCGAGCAGCCGCTCAGTATTGAGGAAAAAGAAGGGTCGTCGTTAGG
ACTGATTGGCGATCTCGATAAAGTCTCTACAGAGACTGTACCGTTGATATTACTTGTGCCGAAGAGCCGGCGTGAAGATC
TGGAAAAAGCTCAACTTGCGGAGCGCCTACGTAGTCAGTTCTTTATTGATTATGGCGTGCGCCTGCCGGAAGTATTGTTA
CGCGATGGCGAGGGCCTGGACGATAACAGCATCGTATTGTTGATTAATGAGATCCGTGTTGAACAATTTACGGTCTATTT
TGATTTGATGCGAGTGGTAAATTATTCCGATGAAGTTGTTTCCTTTGGCATTAATCCAACAATCCATCAGCAAGGTAGCA
GTCAGTATTTCTGGGTAACGCATGAAGAGGGGGAGAAACTCCGGGAGCTTGGCTATGTGTTGCGGAACGCGCTTGATGAG
CTTTACCACTGTCTGGCGGTGACGCTGGCGCGCAACGTCAATGAATATTTCGGTATTCAGGAAACAAAACATATGCTGGA
CCAACTGGAAGCGAAATTTCCTGATTTACTTAAAGAAGTGCTCAGACATGCCACGGTACAACGTATATCTGAAGTTTTGC
AGCGTTTGTTAAGCGAACGTGTTTCCGTGCGTAATATGAAATTAATTATGGAAGCGCTCGCATTGTGGGCGCCAAGAGAA
AAAGATGTCATTAACCTTGTGGAGCATATTCGTGGAGCAATGGCGCGTTATATTTGTCATAAATTCGCCAATGGCGGCGA
ATTACGAGCAGTAATGGTATCTGCTGAAGTTGAGGATGTTATTCGCAAAGGGATCCGTCAGACCTCTGGCAGTACCTTCC
TCAGCCTTGACCCGGAAGCCTCCGCTAATTTGATGGATCTCATTACACTTAAGTTGGATGATTTATTGATTGCACATAAA
GATCTTGTCCTCCTTACGTCTGTCGATGTCCGTCGATTTATTAAGAAAATGATTGAAGGTCGTTTTCCGGATCTGGAGGT
TTTATCTTTCGGTGAGATAGCAGATAGCAAGTCAGTGAATGTTATAAAAACAATATAA

Protein sequence :
MLLSLLNSARLRPELLILVLMVMIISMFVIPLPTYLVDFLIALNIVLAILVFMGSFYIDRILSFSTFPAVLLITTLFRLA
LSISTSRLILIEADAGEIIATFGQFVIGDSLAVGFVVFSIVTVVQFIVITKGSERVAEVAARFSLDGMPGKQMSIDADLK
AGIIDADAARERRSVLERESQLYGSFDGAMKFIKGDAIAGIIIIFVNFIGGISVGMTRHGMDLSSALSTYTMLTIGDGLV
AQIPALLIAISAGFIVTRVNGDSDNMGRNIMTQLLNNPFVLVVTAILTISMGTLPGFPLPVFVILSVVLSVLFYFKFREA
KRSAAKPKTSKGEQPLSIEEKEGSSLGLIGDLDKVSTETVPLILLVPKSRREDLEKAQLAERLRSQFFIDYGVRLPEVLL
RDGEGLDDNSIVLLINEIRVEQFTVYFDLMRVVNYSDEVVSFGINPTIHQQGSSQYFWVTHEEGEKLRELGYVLRNALDE
LYHCLAVTLARNVNEYFGIQETKHMLDQLEAKFPDLLKEVLRHATVQRISEVLQRLLSERVSVRNMKLIMEALALWAPRE
KDVINLVEHIRGAMARYICHKFANGGELRAVMVSAEVEDVIRKGIRQTSGSTFLSLDPEASANLMDLITLKLDDLLIAHK
DLVLLTSVDVRRFIKKMIEGRFPDLEVLSFGEIADSKSVNVIKTI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
invA YP_217815.1 invasion protein Virulence SPI-1 Protein 0.0 100
invA NP_457290.1 possible secretory protein (associated with virulence) Virulence SPI-1 Protein 0.0 100
invA NP_806499.1 virulence-associated secretory protein Virulence SPI-1 Protein 0.0 100
invA NP_461817.1 needle complex export protein Virulence SPI-1 Protein 0.0 100
ECs3731 NP_311758.1 EivA Not tested LIM Protein 3e-179 65
invA AAS66860.1 InvA Not tested SSR-2 Protein 3e-166 64
ysaV AAS66840.1 YsaV Not tested SSR-1 Protein 7e-144 55
lssD AAO18050.1 LssD Virulence TTSS locus Protein 1e-95 42
YPO0266 YP_002345347.1 secretion system apparatus protein SsaV Virulence Not named Protein 4e-88 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TY21A_14135 YP_007927069.1 invasion protein InvA VFG0557 Protein 0.0 100
TY21A_14135 YP_007927069.1 invasion protein InvA VFG1006 Protein 4e-171 65
TY21A_14135 YP_007927069.1 invasion protein InvA VFG1780 Protein 6e-144 54
TY21A_14135 YP_007927069.1 invasion protein InvA VFG0064 Protein 1e-97 43
TY21A_14135 YP_007927069.1 invasion protein InvA VFG0384 Protein 4e-99 43
TY21A_14135 YP_007927069.1 invasion protein InvA VFG0198 Protein 2e-93 42