Gene Information

Name : I872_07900 (I872_07900)
Accession : YP_007923812.1
Strain : Streptococcus oligofermentans AS 1.3089
Genome accession: NC_021175
Putative virulence/resistance : Resistance
Product : erythromycin resistance protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1593894 - 1594631 bp
Length : 738 bp
Strand : +
Note : COG0030 Dimethyladenosine transferase (rRNA methylation)

DNA sequence :

ATGAACAAAAATATAAAATATTCTCAAAACTTTTTAACGAGTGAAAAAGTACTCAACCAAATAATAAAACAATTGAATTT
AAAAGAAACCGATACCGTTTACGAAATTGGAACAGGTAAAGGGCATTTAACGACGAAACTGGCTAAAATAAGTAAACAGG
TAACGTCTATTGAATTAGACAGTCATCTATTCAACTTATCGTCAGAAAAATTAAAACTGAATACTCGTGTCACTTTAATT
CACCAAGATATTCTACAGTTTCAATTCCCTAACAAACAGAGGTATAAAATTGTTGGGAATATTCCTTACCATTTAAGCAC
ACAAATTATTAAAAAAGTGGTTTTTGAAAGCCGTGCGTCTGACATCTATCTGATTGTTGAAGAAGGATTCTACAAGCGTA
CCTTGGATATTCACCGAACACTAGGGTTGCTCTTGCACACTCAAGTCTCGATTCAGCAATTGCTTAAGCTGCCAGCGGAA
TGCTTTCATCCTAAACCAAAAGTAAACAGTGTCTTAATAAAACTTACCCGCCATACCACAGATGTTCCAGATAAATATTG
GAAGCTATATACGTACTTTGTTTCAAAATGGGTCAATCGAGAATATCGTCAACTGTTTACTAAAAATCAGTTTCATCAAG
CAATGAAACACGCCAAAGTAAACAATTTAAGTACCATTACTTATGAGCAAGTATTGTCTATTTTTAATAGTTATCTATTA
TTTAACGGGAGGAAATAA

Protein sequence :

MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLTTKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLI
HQDILQFQFPNKQRYKIVGNIPYHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHAKVNNLSTITYEQVLSIFNSYLL
FNGRK

• Homologs from PAI DB

Gene	GenBank Accn	Product	Virulance or Resistance	PAI or REI	Alignment Type	E-val	Identity
ermA-3	YP_190052.1	rRNA adenine N-6-methyltransferase	Not tested	Type-II SCCmec	Protein	8e-54	52
unnamed	BAB47663.1	rRNA adenine N-6-methyltransferase	Not tested	Type-III SCCmec	Protein	1e-53	52
unnamed	BAC53825.1	rRNA adenine N-6-methyltransferase	Not tested	SRImec-III and SCCmec-III region	Protein	1e-53	52
ermA	BAC57474.1	rRNA methylase	Not tested	Type-IIIinv SCCmec	Protein	6e-54	52
ermA	BAA82205.1	rRNA adenine N-6-methyltransferase	Not tested	Type-II SCCmec	Protein	6e-54	52
ermA1	YP_039522.1	rRNA adenine N-6-methyltransferase 1	Not tested	Type-II SCCmec	Protein	8e-54	52
ermA	NP_370576.1	rRNA methylase	Not tested	Type-II SCCmec	Protein	8e-54	52
ermA	NP_373288.1	rRNA methylase	Not tested	Type-II SCCmec	Protein	8e-54	52
ermC	NP_273130.1	rRNA adenine N-6-methyltransferase	Not tested	IHT-A	Protein	3e-57	51

• Homologs from CARD and BacMet (resistance genes)

Gene	GenBank Accn	Product	ID of source DB	Alignment Type	E-val	Identity
I872_07900	YP_007923812.1	erythromycin resistance protein	AM410044.gene14.p01	Protein	9e-112	99
I872_07900	YP_007923812.1	erythromycin resistance protein	AM903082.gene3.p01	Protein	9e-112	99
I872_07900	YP_007923812.1	erythromycin resistance protein	AM180355.1.gene2259.	Protein	9e-111	98
I872_07900	YP_007923812.1	erythromycin resistance protein	AM180355.1.gene2254.	Protein	9e-111	98
I872_07900	YP_007923812.1	erythromycin resistance protein	M64090.gene.p01	Protein	2e-56	53
I872_07900	YP_007923812.1	erythromycin resistance protein	NC_002952.2859615.p0	Protein	4e-54	52
I872_07900	YP_007923812.1	erythromycin resistance protein	NC_002745.1123579.p0	Protein	4e-54	52
I872_07900	YP_007923812.1	erythromycin resistance protein	NC_002745.1124852.p0	Protein	4e-54	52
I872_07900	YP_007923812.1	erythromycin resistance protein	NC_009782.5559229.p0	Protein	4e-54	52
I872_07900	YP_007923812.1	erythromycin resistance protein	NC_002758.1120012.p0	Protein	4e-54	52
I872_07900	YP_007923812.1	erythromycin resistance protein	NC_002952.2859614.p0	Protein	4e-54	52
I872_07900	YP_007923812.1	erythromycin resistance protein	NC_002745.1122822.p0	Protein	4e-54	52
I872_07900	YP_007923812.1	erythromycin resistance protein	NC_002745.1124324.p0	Protein	4e-54	52
I872_07900	YP_007923812.1	erythromycin resistance protein	NC_002745.1125313.p0	Protein	4e-54	52
I872_07900	YP_007923812.1	erythromycin resistance protein	AJ313523.1.orf0.gene	Protein	7e-54	52
I872_07900	YP_007923812.1	erythromycin resistance protein	NC_009782.5559087.p0	Protein	4e-54	52
I872_07900	YP_007923812.1	erythromycin resistance protein	NC_002758.1121630.p0	Protein	4e-54	52
I872_07900	YP_007923812.1	erythromycin resistance protein	V01278.gene.p01	Protein	2e-58	52
I872_07900	YP_007923812.1	erythromycin resistance protein	M15332.gene.p01	Protein	2e-53	51
I872_07900	YP_007923812.1	erythromycin resistance protein	NC_007792.3912746.p0	Protein	4e-57	51
I872_07900	YP_007923812.1	erythromycin resistance protein	NC_010686.6295746.p0	Protein	1e-57	51
I872_07900	YP_007923812.1	erythromycin resistance protein	NC_010685.6295744.p0	Protein	1e-57	51
I872_07900	YP_007923812.1	erythromycin resistance protein	NC_007209.3523503.p0	Protein	1e-57	51